| Project/Area Number |
26893015
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Psychiatric science
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| Research Institution | Tohoku University |
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Principal Investigator |
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| Project Period (FY) |
2014-08-29 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Keywords | 臨床精神医学 / 統合失調症 / ARMS / 自閉症スペクトラム障害 / 精神病発症リスク状態 |
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| Outline of Final Research Achievements |
Autism spectrum "like" symptoms are sometimes observed in Ultra-High Risk (UHR) patients for psychosis. We tried to evaluate autism spectrum symptoms (using Autism spectrum Quotient-Japanese version (AQ-J) and Social Communication Questionnaire (SCQ)) in UHR patients who had been followed-up at our specialized clinic for early psychosis, and examined relationships between these scores and both subthreshold psychotic symptoms (by Comprehensive Assessment of ARMS (CAARMS)) and whether they converted to psychosis or not.
Two out of 39 people exceeded the SCQ cutoff value, which confirmed the previous study. Regarding the AQ-J (two types of cutoff values are suggested for Japanese), however, 22 of 50 samples scored over 26 points, and seven over 33 points. The AQ-J total score and “social skills” score were significantly correlated with the “perceptual abnormalities” score in the CAARMS. The mean score of the AQ-J was high among the converters, though not statistically significant.
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