Elucidation of the pain disorder onset with depression model rat
| Project/Area Number |
26893084
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Surgical dentistry
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| Research Institution | Niigata University |
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Principal Investigator |
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| Project Period (FY) |
2014-08-29 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Keywords | 疼痛性障害 / うつ病 / セロトニン / 神経ペプチド / うつ病モデルラット / 神経生理 |
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| Outline of Final Research Achievements |
Using a depression model rat, in order to elucidate the neural mechanisms of depression-related type pain disorder, escape behavior analysis by behavioral experiments, anti-depressants for the electrophysiological analysis and pain disorders of neural activity that are involved in pain central of medicine and tried to analysis of peripheral pharmacological action. In addition, related pain disorders and brain serotonin decrease, the presence of the neuropeptides that affect the peripheral receptors to receive the pain, was studied relief of pain disorders due to the increase in brain serotonin.
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Report
(3 results)
Research Products
(2 results)
