Study of the pharynx and larynx sense to modify the swallowing reflex.

Research Project

Project/Area Number	26893088
Research Category	Grant-in-Aid for Research Activity Start-up
Allocation Type	Single-year Grants
Research Field	Social dentistry
Research Institution	Niigata University
Principal Investigator	Takatsuji Hanako 新潟大学, 医歯(薬)学総合研究科, 非常勤講師 (80736679)
Project Period (FY)	2014-08-29 – 2016-03-31
Project Status	Completed (Fiscal Year 2015)
Budget Amount *help	¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000) Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000) Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Keywords	嚥下 / 咽頭 / 喉頭 / のどごし / TRPチャネル / TRPV1 / TRPM8 / 摂食・嚥下リハビリテーション / 痛覚 / うま味 / 脂肪 / 電気刺激 / 舌咽神経咽頭枝
Outline of Final Research Achievements	Distribution of TRP channels in sensory nerves ( pharyngeal branch of glossopharyngeal nerve and superior laryngeal nerve ) under superior and inferior ganglion, nodose ganglion and oral mucosa was examined by histological techniques. Based on those results, we examined the modulation of taste receptors in the pharynx, larynx area by the TRP channel inhibitors. Furthermore, we examined the modulation of swallowing induction by the TRP channel inhibitors.