Impact of periodontal disease and decreased masticatory performance on the risk and incidence of atherosclerosis

• Project/Area Number: 26893141
• Research Category: Grant-in-Aid for Research Activity Start-up
• Allocation Type: Single-year Grants
• Research Field: Prosthodontics/ Dental materials science and
• Research Institution: Osaka University
• Principal Investigator: Kida Momoyo 大阪大学, 歯学部附属病院, 医員 (10733082)
• Project Period (FY): 2014-08-29 – 2017-03-31
• Project Status: Completed (Fiscal Year 2016)
• Budget Amount: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000); Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
• Keywords: 咀嚼能率 / 歯周病 / 動脈硬化 / メタボリックシンドローム / 歯学 / 循環器・高血圧 / 疫学

Outline of Final Research Achievements

This study assessed the relationship between oral health and general health in a Japanese urban population. Blow results were found.
1. Periodontitis may be a risk factor for carotid atherosclerosis. 2. Decreased masticatory performance might be related to carotid atherosclerosis. This relationship is independent from periodontal disease. 3. The regular utilization of dental care services is a factor influencing masticatory performance.

Research Products

• [Journal Article] Relationship between metabolic syndrome and objective masticatory performance in a Japanese general population: the Suita study. (2017)
  • Author(s): Miki Kikui, Takahiro Ono, Yoshihiro Kokubo, Momoyo Kida, Takayuki Kosaka, Masaaki Yamamoto, Takashi Nokubi, Makoto Watanabe, Yoshinobu Maeda, Yoshihiro Miyamoto.
  • Journal Title: Journal of Dentistry Volume: 56 Pages: 53-57
  • DOI: 10.1016/j.jdent.2016.10.014
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Relationship between Metabolic Syndrome Components and Periodontal Disease in a Japanese General Population: the Suita Study (2017)
  • Author(s): Miki Kikui, Yoshihiro Kokubo, Takahiro Ono, Momoyo Kida, Takayuki Kosaka, Masaaki Yamamoto, Makoto Watanabe, Yoshinobu Maeda, Yoshihiro Miyamoto.
  • Journal Title: Journal of Atherosclerosis and Thrombosis Volume: 24 Issue: 5 Pages: 495-507
  • DOI: 10.5551/jat.33761
  • NAID: 130005631699
  • ISSN: 1340-3478, 1880-3873
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] A multifactorial model of masticatory performance: the Suita study (2016)
  • Author(s): Kosaka T, Ono T, Kida M, Kikui M, Yamamoto M, Yasui S, Nokubi T, Maeda Y, Kokubo Y, Watanabe M, Miyamoto Y
  • Journal Title: J Oral Rehabil Volume: 43 Issue: 5 Pages: 340-347
  • DOI: 10.1111/joor.12371
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] 半量グミゼリーによる咀嚼能率スコア法の開発 (2016)
  • Author(s): 小野高裕，安井栄，金田恒，菊池さつき，來田百代、高阪貴之，菊井美希，前田芳信，野首孝祠
  • Journal Title: 日本咀嚼学会雑誌 Volume: 26 Pages: 9-13
  • Peer Reviewed
• [Journal Article] Does the utilization of dental services associate with masticatory performance in a Japanese urban population?: the Suita study (2015)
  • Author(s): Miki Kikui, TakahiroOno, Momoyo Kida, Takayuki Kosaka,Masaaki Yamamoto, Yoko Yoshimuta, Sakae Yasui, Takashi Nokubi, YoshinobuMaeda, Yoshihiro Kokubo, Makoto Watanabe, Yoshihiro Miyamoto
  • Journal Title: Clinical and Experimental Dental Research Volume: 26 OCT Pages: 1-6
  • Peer Reviewed / Open Access
• [Journal Article] Salivary inflammatory cytokines may be novel markers of carotid atherosclerosis in a Japanese general population: the Suita study. (2014)
  • Author(s): Kosaka T, Kokubo Y, Ono T, Sekine S, Kida M, Kikui M, Yamamoto M, Watanabe M, Amano A, Maeda Y, Miyamoto Y.
  • Journal Title: Atherosclerosis. Volume: 237(1) Issue: 1 Pages: 123-8
  • DOI: 10.1016/j.atherosclerosis.2014.08.046
  • Peer Reviewed
• [Journal Article] The effect of periodontal status and occlusal support on masticatory performance: the Suita study. (2014)
  • Author(s): Kosaka, T., Ono, T., Yoshimuta, Y., Kida, M., Kikui, M., Nokubi, T., Maeda, Y., Kokubo, Y., Watanabe, M., Miyamoto, Y.
  • Journal Title: Journal of Clinical Periodontology Volume: 41 Issue: 5 Pages: 497-503
  • DOI: 10.1111/jcpe.12241
  • Peer Reviewed
• [Journal Article] 上顎腫瘍術後患者における早期顎義歯の有効性 (2014)
  • Author(s): 伊谷康弘，小野高裕，山本雅章，城下尚子，藤原茂弘，來田百代，高阪貴之，皆木祥伴，藤尾隆史，菊井美希，徳田佳嗣，村上和裕，西浦麻侑，前田芳信
  • Journal Title: 日本顎顔面補綴学会機関誌 Volume: 37 Pages: 1-9
  • Peer Reviewed
• [Presentation] 都市部一般住民における咀嚼能率の縦断的推移－吹田研究－ (2016)
  • Author(s): 高阪貴之，小野高裕，來田百代，菊井美希，橋本栄，藤井克則，山本雅章，前田芳信，金田恒，小久保喜弘，野首孝祠
  • Organizer: 日本咀嚼学会第27回学術大会
  • Place of Presentation: 広島大学（広島県広島市）
  • Year and Date: 2016-11-05
• [Presentation] 歯数の自己認識に見るオーラルリテラシーと咀嚼能率との関連 －吹田研究－ (2016)
  • Author(s): 橋本 栄，小野高裕，來田百代，高阪貴之，菊井美希，藤井克則，山本雅章，野首孝祠，小久保喜弘，前田芳信
  • Organizer: 日本咀嚼学会第27回学術大会
  • Place of Presentation: 広島大学（広島県広島市）
  • Year and Date: 2016-11-05
• [Presentation] 咀嚼能力の低下および歯周病とメタボリックシンドロームとの関連－吹田研究－ (2015)
  • Author(s): 菊井美希，小野高裕，山本雅章，來田百代，高阪貴之，橋本栄，藤井克則， 野首孝祠，小久保喜弘，前田芳信
  • Organizer: 日本咀嚼学会第26回学術大会
  • Place of Presentation: 鶴見大学会館（横浜市、神奈川県）
  • Year and Date: 2015-09-25
• [Presentation] 都市部一般住民におけるメタボリックシンドロームと咀嚼能力との関連性－ 吹田研究－ (2015)
  • Author(s): 菊井美希，小野高裕，來田百代，高阪貴之，野首孝祠，小久保喜弘，前田芳信
  • Organizer: 日本補綴歯科学会第124回学術大会
  • Place of Presentation: 大宮ソニックシティ―(さいたま市、埼玉県)
  • Year and Date: 2015-05-30
• [Presentation] 新しい半量グミゼリーによる咀嚼能率スコア法の開発 (2014)
  • Author(s): 安井栄，小野高裕，來田百代，高阪貴之，菊井美希，前田芳信，澤井明香，野首孝祠
  • Organizer: 日本咀嚼学会第25回総会・学術大会
  • Place of Presentation: 静岡
  • Year and Date: 2014-09-21
• [Presentation] 歯科受診行動は都市部一般住民の咀嚼能力に影響するか？－吹田研究－ (2014)
  • Author(s): 菊井美希，小野高裕，來田百代，高阪貴之，吉牟田陽子，安井栄，山本雅章，野首孝祠，小久保喜弘，前田芳信
  • Organizer: 日本咀嚼学会第25回総会・学術大会
  • Place of Presentation: 静岡
  • Year and Date: 2014-09-21
• [Presentation] 都市部一般住民における咀嚼能率低下のリスク因子－吹田研究－ (2014)
  • Author(s): 來田百代，小野高裕，高阪貴之，菊井美希，吉牟田陽子，安井栄，山本雅章，野首孝祠，小久保喜弘，前田芳信
  • Organizer: 日本咀嚼学会第25回総会・学術大会
  • Place of Presentation: 静岡
  • Year and Date: 2014-09-21