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A Basic Study to Develop Effective Methods to Reduce Lymphedema

Research Project

Project/Area Number 26893300
Research Category

Grant-in-Aid for Research Activity Start-up

Allocation TypeSingle-year Grants
Research Field Fundamental nursing
Research InstitutionKanazawa Medical University

Principal Investigator

ASANO Kimi  金沢医科大学, 看護学部, 助教 (10735351)

Project Period (FY) 2014-08-29 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Keywordsリンパ浮腫 / メスマウス / リンパ流 / インドシアニングリーン / 腹壁リンパ節 / 下肢 / マウス
Outline of Final Research Achievements

This study aimed to establish an animal model of lymphedema, in order to examine its mechanisms, as well as effective methods to reduce or completely cure it. In mice, the lymph flows from the hind limb to the heart through the inguinal lymph node, abdominal and thoracic lymphatic vessels, and axillary lymph node, in this order. After inguinal lymphadenectomy, hind-limb lymphedema occurs, and persists for approximately 3 days. The study did not succeed in establishing a model of lymphedema, possibly due to the following: the mouse hind-limb lymphatic system under the skin is extensive, and the lymph flows through the abdominal and thoracic lymphatic vessels toward the axillary lymph node, consequently preventing hind-limb lymphedema from persisting long after inguinal lymphadenectomy.

Report

(3 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Annual Research Report
  • Research Products

    (8 results)

All 2016 2015 Other

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (5 results) Remarks (1 results)

  • [Journal Article] 未経験者による三角筋筋肉内注射の位置決め器具の使用に関する正確性と簡便性の生体での検討2016

    • Author(s)
      向井 加奈恵,小松 恵美,中島 由加里,浦井 珠恵,浅野 きみ,中谷 壽男
    • Journal Title

      形態・機能

      Volume: 14(2) Pages: 75-83

    • NAID

      130005144368

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Anatomical investigation of position of crossing of superficial branch of radial nerve and cephalic vein and its frequency2015

    • Author(s)
      Kanae Mukai, Emi Komatsu, Tamae Urai, Yukari Nakajima, Kimi Asano, Noriyuki Ozaki, Toshio Nakatani
    • Journal Title

      Structure and Function

      Volume: 14(1) Pages: 3-11

    • NAID

      130005100065

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Presentation] 鼠径リンパ節を廓清した下腿に作製した創傷は治癒が遅延するか2016

    • Author(s)
      中谷壽男、小松恵美、浅野きみ、向井加奈恵、浦井珠恵、中島由加里
    • Organizer
      第45回日本創傷治癒学会
    • Place of Presentation
      JPタワーホール&カンファレンス:JPタワー・KITTE(東京都千代田区)
    • Year and Date
      2016-11-30
    • Related Report
      2015 Annual Research Report
  • [Presentation] Estradiol Benzoateの創部塗布による皮膚創傷治癒への効果―肉眼的検討―2016

    • Author(s)
      向井加奈恵、浦井珠恵、浅野きみ、中島由加里、須釜淳子、中谷壽男
    • Organizer
      第45回日本創傷治癒学会
    • Place of Presentation
      JPタワーホール&カンファレンス:JPタワー・KITTE(東京都千代田区)
    • Year and Date
      2016-11-30
    • Related Report
      2015 Annual Research Report
  • [Presentation] リンパ節切除とリンパ管切断による皮膚創傷治癒への影響2016

    • Author(s)
      小松恵美、向井加奈恵、浦井珠恵、浅野きみ、中島由加里、中谷壽男
    • Organizer
      第17回日本褥瘡学会学術集会
    • Place of Presentation
      仙台国際センター(宮城県仙台市)
    • Year and Date
      2016-08-28
    • Related Report
      2015 Annual Research Report
  • [Presentation] 三角筋・中殿筋の筋肉内注射(筋注)部位選定の方法2016

    • Author(s)
      中谷壽男、中島由加里、小松恵美、浦井珠恵、浅野きみ、向井加奈恵
    • Organizer
      第121回日本解剖学会総会・全国学術集会
    • Place of Presentation
      ビッグパレットふくしま(福島県郡山市)
    • Year and Date
      2016-03-27
    • Related Report
      2015 Annual Research Report
  • [Presentation] 三角筋筋肉内注射位置決め器具の使用未経験者における測定部位のずれの検討2015

    • Author(s)
      浦井珠恵、向井加奈恵、小松恵美、中島由加里、浅野きみ、中谷壽男
    • Organizer
      コ・メディカル形態機能学会 第14回学術集会
    • Place of Presentation
      埼玉医科大学川角キャンパス(埼玉県入間郡)
    • Year and Date
      2015-09-26
    • Related Report
      2015 Annual Research Report
  • [Remarks] 金沢医科大学

    • URL

      http://www.kanazawa-med.ac.jp/

    • Related Report
      2015 Annual Research Report

URL: 

Published: 2014-09-09   Modified: 2017-05-10  

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