| Project/Area Number |
26893321
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Epidemiology and preventive medicine
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| Research Institution | University of Occupational and Environmental Health, Japan |
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Principal Investigator |
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| Project Period (FY) |
2014-08-29 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Keywords | mesothelioma / epidemiology / asbestos / burden of disease / global burden / birth cohort |
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| Outline of Final Research Achievements |
Goal:The current study descriptively analysed national mortality data with regard to their availability and referability for extrapolation, and extrapolated the referable data to estimate the global burden of mesothelioma deaths.
Result:The global numbers and rates of mesothelioma deaths increased each year. The 55 referable countries recorded 14,601 mesothelioma deaths per year over the two most recent years with available data, yielding a two-year mortality rate of 9.89 (95% CI, 5.45-15.25) deaths per million per year. By extrapolating these numbers, the unadjusted annual global burden of mesothelioma deaths was estimated as 68,800, which ranged between 49,900 and 53,400 after adjusting for selected attributes. Our estimates were reasonably close to the previously reported values, albeit on the higher end.
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