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The genotypic classification of Mycobacterium tuberculosis and risk factor investigation on the basis of the epidemiology information in young tuberculosis patient

Research Project

Project/Area Number 26893338
Research Category

Grant-in-Aid for Research Activity Start-up

Allocation TypeSingle-year Grants
Research Field Hygiene and public health
Research InstitutionOsaka City Institute of Public Health and Environmental Sciences

Principal Investigator

Yamamoto Kaori  大阪市立環境科学研究所, その他部局等, 研究員 (70649011)

Project Period (FY) 2014-08-29 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Keywords結核 / 遺伝系統 / 若年者 / 北京型株新興型 / あいりん / 北京型株 / 新興型 / 若年 / 北京型
Outline of Final Research Achievements

The modern subfamily of Beijing lineage, one of the genetic groups of Mycobacterium tuberculosis, is considered more virulent than other genetic groups. In this study, I investigated genetic situation to elucidate situation of spread of the tubercle bacilli isolated from two patients groups: younger than 40 years and resident in the Airin area. As a result, it was revealed that the proportion of strains belonging to the modern Beijing subfamilies has increased from both patients populations.In Airin area, TB patients aged 50 to 80 accounted for more than 80% of the total population. The situation suggests that the modern Beijing subfamily strains has increased in not only young fellows but also old and middle aged people.

Report

(3 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Annual Research Report
  • Research Products

    (3 results)

All 2016 2015

All Journal Article (1 results) (of which Open Access: 1 results,  Acknowledgement Compliant: 1 results) Presentation (2 results)

  • [Journal Article] 大阪市における結核菌の分子疫学解析状況(2012-2014)2015

    • Author(s)
      山本香織、中村寛海、小向 潤、和田崇之、梅田 薫、小笠原 準、平井有紀、平山照雄、長谷 篤、松本健二、西尾孝之
    • Journal Title

      大阪市立環境科学研究所報告 調査・研究年報

      Volume: 77 Pages: 21-26

    • Related Report
      2015 Annual Research Report
    • Open Access / Acknowledgement Compliant
  • [Presentation] 大阪市あいりん地域における結核菌伝播状況解析(2006~2014)2016

    • Author(s)
      山本香織、和田崇之、小向潤、長谷 篤、松本健二、下内昭、山本太郎
    • Organizer
      第91回日本結核病学会総会
    • Place of Presentation
      石川県立音楽堂(金沢市)
    • Year and Date
      2016-05-26
    • Related Report
      2015 Annual Research Report
  • [Presentation] 大阪市あいりん地域における結核菌分子疫学調査2015

    • Author(s)
      山本香織、和田崇之、小向潤、松本健二、下内昭、山本太郎
    • Organizer
      第74回日本公衆衛生学会
    • Place of Presentation
      長崎ブリックホール(長崎市)
    • Year and Date
      2015-11-04
    • Related Report
      2015 Annual Research Report

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Published: 2014-09-09   Modified: 2017-05-10  

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