Research Project
Grant-in-Aid for Developmental Scientific Research
Achievements of the project is as follows:Kinoshita established a method for determination of bradykinine using alkaline ninhydrin reagent and applied it to the studies on enzymatic degradation of gradykinine in human plasma. Nimura established a method for determination of glutathione in human blood using o-phthalaldehyde reagent. Diluted blood could be directly injected into a chromatograph without pre-treatment. Imai developed a method for determination of catecholamines catecholamines and L-dopa using ethylenediamine and applied it to monitor these substances in biological samples. Tsuji synthesized 1-bromoacetylpyrene for the fluorescent labeling of carboxyl group and employed it to estimate sulfateconjugated bile acids in biological fluids. Nambara prepared 9- or 1-anthroylnitrile as a fluorescent labeling reagents for hydroxy group and applied it to the determination of various steroids and bile acids. Ohkura devised a method to determine histidine decarboxilase activity by measuring histamine fluorometrically.New determination methods established in this research project were extremely effective for the ultramicrotracing of such biological materials.
All Other
All Publications (10 results)
