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Investigation on the Pathophysiology of the Earliest Primary Open-angle Glaucoma

Research Project

Project/Area Number 59440073
Research Category

Grant-in-Aid for General Scientific Research (A)

Allocation TypeSingle-year Grants
Research Field Ophthalmology
Research InstitutionNiigata University

Principal Investigator

IWATA Kazuo  Niigata University・ School of medicine Professor Dept. Ophthalmology, 医学部, 教授 (10018301)

Co-Investigator(Kenkyū-buntansha) KUROSAWA Akimitsu  Niigata University・ Niigata University Hospital Dept. Ophthalmology Assistant, 医学部附属病院, 助手 (90126409)
NANBA Katsuhiko  Niitata University・ Niigata University Hospital Dept. Ophthalmology Lecturer, 医学部附属病院, 講師 (80018738)
Project Period (FY) 1984 – 1986
Project Status Completed (Fiscal Year 1986)
Budget Amount *help
¥11,000,000 (Direct Cost: ¥11,000,000)
Fiscal Year 1986: ¥1,500,000 (Direct Cost: ¥1,500,000)
Fiscal Year 1985: ¥1,500,000 (Direct Cost: ¥1,500,000)
Fiscal Year 1984: ¥8,000,000 (Direct Cost: ¥8,000,000)
KeywordsStereoscopy / Stereo-chronoscopy / 経時的立体観察 / 視神経乳頭陥凹 / クロノスコピー
Research Abstract

In this research, it was reconfirmed that the accurate alignment between the fundus camera and the eye was essential on stereo-chronoscopy. For this purpose, the stereo-chronoscopic fundus camera was modified by changing the scale of the monitor pattern and by super-imposing the pattern and the light of corneal reflex with the fundus image onto the film. With this modification, the alignment could be obtained and checked more easily and accurately. The follow-up study on the optic disc change by stereo-chronoscopy revealed no change in eyes of the normal patients but changes from slight to severe degree in the cup of ocular hypertensive and glaucomatous eyes. Even slight changes in the cup of the eye with well controlled intraocular pressure could be detected by stereo-chronoscopy, while those eyes did not show any change in visual field and any change in the cup with usual stereophotographs. We noticed that the changes in the cup show quite different stereoscopic images by stereo-chronoscopy from those caused by misalignment. The cup generally enlarged during the follow-up period shows the impression of remoteness in the one half of the cup and the impression of nearness in the other half of the cup. The cup with a small part slightly changed gives the impression of remoteness or nearness. These stereoscopic images can be interpreted by the binocular parallax which the true changes in the cup produce. These stereoscopic images could not be nulled by azimuthal rotation of the photographs.
From these results, stereo-chronoscopy can be said usefull in early detection of the glaucomatous changes in the optic disc.

Report

(2 results)
  • 1986 Final Research Report Summary
  • 1985 Annual Research Report
  • Research Products

    (5 results)

All Other

All Publications (5 results)

  • [Publications] 難波克彦,岩田和雄: 日本眼光学学会誌. 7. 7-11 (1986)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1986 Final Research Report Summary
  • [Publications] 難波克彦,岩田和雄: 日本眼科学会誌.

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1986 Final Research Report Summary
  • [Publications] Nanba, Katsuhiko Iwata, Kazuo: "A Method to Check the Alignment of Stereochronoscopic Fundus Photography." J. Ophthalmol. Opt. Soc. Jpn.7. 7-11 (1986)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1986 Final Research Report Summary
  • [Publications] Nanba, Katsuhiko Iwata, Kazuo: "Follow-up Study on the Glaucomatous Optic Disc Cupping. The Stereoscopic images from the changes in the cup." Acta Soc. Ophthalmol. Jpn.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1986 Final Research Report Summary
  • [Publications] K.カンオウ日本眼光学学会誌.

    • Related Report
      1985 Annual Research Report

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Published: 1987-03-31   Modified: 2016-04-21  

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