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Effect of selection for body weight on viability of embryos in mice.

Research Project

Project/Area Number 59480075
Research Category

Grant-in-Aid for General Scientific Research (B)

Allocation TypeSingle-year Grants
Research Field 畜産学(含草地学)
Research InstitutionHOKKAIDO UNIVERSITY

Principal Investigator

SHIMIZU Hiroshi  FACULTY OF AGRICULTURE, HOKKAIDO UNIVERSITY Associate Prof., 農学部, 助教授 (90001453)

Co-Investigator(Kenkyū-buntansha) UEDA Junji  FACULTY OF AGRICULTURE, HOKKAIDO UNIVERSITY Instructor, 農学部, 助手 (50002374)
Project Period (FY) 1984 – 1986
Project Status Completed (Fiscal Year 1986)
Budget Amount *help
¥6,600,000 (Direct Cost: ¥6,600,000)
Fiscal Year 1986: ¥1,000,000 (Direct Cost: ¥1,000,000)
Fiscal Year 1985: ¥1,000,000 (Direct Cost: ¥1,000,000)
Fiscal Year 1984: ¥4,600,000 (Direct Cost: ¥4,600,000)
Keywordsbody weight selection / ovulation rate / implantation rate / embryo loss / viability / 産子数
Research Abstract

It was shown that there were apparent differences in litter size among three selected strains for juvenile body weight in mice, that was, M-strain was selected for male only, F-strain was selected for female only, and MF-strain was selected for both sexes. MF-strain was most increased in body weight and followed by F- and M-strains. However, the strain which most increased in litter size, was F-strain and, followed by M-strain. The litter size of MF-strain was not significantly different from C-strain (unselected strain). Objects of this project were to investigate some factors affecting a litter size and genetic relationships between body weight and reproductive traits. The following results were obtained.
1. F-strain showed the most increase in ovulation rate and the least loss of eggs before implantation and of embryos after implantation, while MF-strain ovulated as much as F-strain but lost much eggs and embryos before parturition. M-strain showed the increased ovulation rate following to F- and MF-strain, and the loss before implantation as less as F-strain but much loss in embryos.
2. Maternal effect on the loss of embryos was examined by transfering embryos from C-strain to M-, F- and C-strains. The results showed that the maternal effect was more important for survival of embryos than the effect of embryo itself and uterine condition of F-strain was superior to other strains for survival of embryos.
3. Factors and mechanism which caused the difference in reproductive traits between F- and M- strains could not be interpretated.

Report

(1 results)
  • 1986 Final Research Report Summary
  • Research Products

    (4 results)

All Other

All Publications (4 results)

  • [Publications] 清水弘,栗田栄,上田純治,八戸芳夫: 日本畜産学会報. 56. 495-504 (1985)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1986 Final Research Report Summary
  • [Publications] 森匡,清水弘,上田純治,八戸芳夫: 北海道大学農学部邦文紀要. 14. 403-408 (1985)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1986 Final Research Report Summary
  • [Publications] HIROSHI SHIMIZU, TAKASHI AWATA, JUNJI UEDA AND YOSHIO HACHINOHE: "Principal Component Analysis for the Size of Skeletal Bones in Mice." Japanese Journal of Zootechnical Science. 56. 495-504 (1985)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1986 Final Research Report Summary
  • [Publications] TADASHI MORI, HIROSHI SHIMIZU,JUNJI UEDA AND YOSHIO HACHINOHE: "Effect of the Selection for Increased Body Weight on the Reproductive Traits of the Female Mice." Memoris of the Faculty of Agriculture Hokkaido University. 14. 403-408 (1985)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1986 Final Research Report Summary

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Published: 1987-03-31   Modified: 2016-04-21  

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