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A Reseach for biorhythm in school refusals

Research Project

Project/Area Number 59480240
Research Category

Grant-in-Aid for General Scientific Research (B)

Allocation TypeSingle-year Grants
Research Field Pediatrics
Research InstitutionTokyo Women's Medical College Daini Hospital Department of Pediatrics

Principal Investigator

KUSAKAWA Sanji  Tokyo Women's Medical College Daini Hospital Department of Pediatrics, 医学部, 教授 (90075177)

Co-Investigator(Kenkyū-buntansha) 田村 まり子  東京女子医科大, 学・附属第二病院小児科, 助手
ITOU Keiko  東京女子医科大, 学・附属第二病院小児科, 助手 (70201324)
KIGUCHI Hiroyuki  Tokyo Women's Medical College Daini Hospital Department of Pediatrics, 学・附属第二病院小児科, 講師 (90075739)
UMEZU Ryoji  Tokyo Women's Medical College Daini Hospital Department of Pediatrics, 学・附属第二病院小児科, 講師 (80119908)
MURATA Mitsunori  Tokyo Women's Medical College Daini Hospital Deparlment of Pediatrics, 学・附属第二病院小児科, 教授 (40075239)
TAMURA Mariko  Tokyo Women's Medical College Daini Hospital Dapartment of Pediatrics
Project Period (FY) 1984 – 1986
Project Status Completed (Fiscal Year 1986)
Budget Amount *help
¥5,600,000 (Direct Cost: ¥5,600,000)
Fiscal Year 1986: ¥1,400,000 (Direct Cost: ¥1,400,000)
Fiscal Year 1985: ¥1,400,000 (Direct Cost: ¥1,400,000)
Fiscal Year 1984: ¥2,800,000 (Direct Cost: ¥2,800,000)
KeywordsSchool refusal / biorhythm / 概日リズム / DSM-【III】分類
Research Abstract

As a constitutional predisposiotion of school refursals we investigated giving a special emphasis on their biorhythm. The checking items were as follows : all night sleep EEG, deep body temperature, serum cortisol (Cor), serum <beta> -endorphin ( <beta> -Ep), urine volume, urinary sodium excretion, urinary catecholamines (CA), skin potential level and heart rate.
The test subjects were 63 cases of school refusals but checking items were somewhat different with one another and,in addition,partially,children who showed only unidentified clinical syndome were included. Further, the school refusals were classified according to DSM- <III> (Diagnostic and Statistical Mannualfor Mental Disorders, <III> rd Edition) and relationships between the classes and the test.results were investigated.
(1)With respect to items of blood <beta> -Ep, urinary sodium excretion, skin potential level and heart rate, the number of subjects who did not show the intrinsic circadian rhythm (24 <+!-> 4 hours cycle) we … More re significantly larger in the group of school refusals than the control group.
(2)As to the all night sleep EEG, the decrease of sleep efficiency index and REM sleep or increase of waking after sleep onset or such that indicated the abnormality of sleep pattern were observed many in the school refusals, however, no discernoble tendency among the types of DSM- <III> was noted.
(3)The results of deep body temperatures in abdominal and plantar regions indicated that in the school refusals and unidentified clinical syndome groups, decrease of the difference between abdominal and plantar temperatures as well as decrease of rhythmical change of plantar temperature usually observed in normal subjects were noted.
(4)Correlations between variables derived from the excretion rhythm of urinary CAs and the levels of adaptive functioning (DSM- <III> , Axis 5) were investigated by means of multivariate analysis. The results showed significant correlations between some variables of CA excretion and the level of adaptative functioning.
From the above results, it was elucidated that the abnormality of school refusals can be identified by various parameters related to biorhythm. Less

Report

(1 results)
  • 1986 Final Research Report Summary

Research Products

(11 results)

All Other

All Publications (11 results)

  • [Publications] 梅津亮二: 小児科学年鑑 1985-'86 小児科の進歩. 5. 182-187 (1985)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1986 Final Research Report Summary
  • [Publications] 梅津亮二: 臨床脳波. 28. 476-480 (1986)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1986 Final Research Report Summary
  • [Publications] 大谷智子: 小児科. 27. 1067-1073 (1986)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1986 Final Research Report Summary
  • [Publications] 梅津亮二: 病態生理. 6. 230-232 (1987)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1986 Final Research Report Summary
  • [Publications] 河野照隆: 自律神経. 23. 394-400 (1986)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1986 Final Research Report Summary
  • [Publications] 塚田和子: 自律神経.

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1986 Final Research Report Summary
  • [Publications] Ryoji Umezu: "All night EEG in school refusals" Progress in Pediatrics. 5. 182-187 (1985)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1986 Final Research Report Summary
  • [Publications] Ryoji Umezu: "All night EEG in school refusals" Clinical Electroencephalography. 28. 476-480 (1986)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1986 Final Research Report Summary
  • [Publications] Tomoko Otani: "All night EEG in school refusals" Pediatrics of JAPAN. 27. 1067-1073 (1986)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1986 Final Research Report Summary
  • [Publications] Ryoji Umezu: "Circadian rhythms in school refusals" Medicina Philosophica. 6. 230-232 (1987)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1986 Final Research Report Summary
  • [Publications] Terutaka Khono: "Invertigation of Circadian rhythms in school Refusals by the Method of Measring Skin Potential Level" The Autonomic Nervous System. 23. 394-400 (1986)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1986 Final Research Report Summary

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Published: 1987-03-30   Modified: 2017-03-27  

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