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Endogenous Sudden Death during Physical Activities and Its Preventive Steps

Research Project

Project/Area Number 59480435
Research Category

Grant-in-Aid for General Scientific Research (B)

Allocation TypeSingle-year Grants
Research Field 体育学
Research InstitutionOsaka College of Physical Education

Principal Investigator

ISEKI Toshiyuki  Osaka College of Physical Education, 体育学部, 教授 (90046657)

Co-Investigator(Kenkyū-buntansha) TAKISE Sadafumi  Osaka College of Physical Education, 体育学部, 助教授 (30067251)
YOSHIDA Seiji  Osaka College of Physical Education, 体育学部, 助教授 (30079181)
高塚 泰次郎  大阪体育大学, 体育学部, 教授 (40163216)
MASUHARA Mitsuhiko  Osaka College of Physical Education, 体育学部, 教授 (40067236)
横山 広之  大阪体育大学, 体育学部, 教授 (20067218)
TAKATSUKA Taijiro  Osaka College of Physical Education
YOKOYAMA Hiroyuki  Osaka College of Physical Education
Project Period (FY) 1984 – 1986
Project Status Completed (Fiscal Year 1986)
Budget Amount *help
¥6,300,000 (Direct Cost: ¥6,300,000)
Fiscal Year 1986: ¥1,500,000 (Direct Cost: ¥1,500,000)
Fiscal Year 1985: ¥2,000,000 (Direct Cost: ¥2,000,000)
Fiscal Year 1984: ¥2,800,000 (Direct Cost: ¥2,800,000)
Keywordssudden death / medical check / adrenocortical insufficiency / Addison's disease / Diving reflex / ANP / Captopril / レニン・アンジオテンシン・アルドステロン系
Research Abstract

1. Statistical Observation of Sudden Death at School
Of 61 pupils who died suddenly at school in the 7-year period from 1978, 16 were found to have had idiopathic cardiomyopathy, congenital heart disease, etc. It is of interest, however, that these pupils died suddenly during school attendance, school hours, and light intensity exercise in a class of physical education. Others were known to have had a heart operation. The number of weak children was also relatively large as compared with that of normal children.
2. Preventive Steps
Following preventive steps are recommended: 1) elucidation of true death causes through the previous findings of clinical examinations and the autopsy, 2) completeness of medical check, 3) enforcement of a comprehensive study from a standpoint of exercise physiology (or sports medicine), 4) building-up of a close connection between physicians and teachers in the treatment of deseased pupils, and 5) preparation for cardiac emergency and the development of the ur … More gent system.
3. Major Findings
Major findings obtained in this study can be summarized as follows.
1) In the Addison's disease with adrenocortical insufficiency performing dynamic exercise, there were little changes in the ACTH, cortisol, aldosterone, and adrenaline; while the PRA and noradrenaline increased markedly. 2) When exercise was given to patients who showed arrhythmias (due probably to the activity change in the autonomic nervous system) in the Diving reflex and Valsalva tests, hyper-response of the hypophyseal-adrenal system was present in some patients, while others were found not to respond at all. Immediately after the end of cycling exercise, two patients showed a severe drop in blood pressure and heart rate. The response of the endocrine glands in these patients was significantly high. 3) Although ANP of normal men started to increase above a resting base-line value at or above the exercise intensity of 150 W, ANP of patients with essential hypertension exhibited a further, systematic increase. Less

Report

(1 results)
  • 1986 Final Research Report Summary

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Published: 1987-03-31   Modified: 2016-04-21  

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