| Project/Area Number |
59870034
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| Research Category |
Grant-in-Aid for Developmental Scientific Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Circulatory organs internal medicine
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| Research Institution | National Cardiovascular Center |
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Principal Investigator |
NIMURA Yasuharu Director-General, National Cardiovascular Center Research Institute, その他, 研究員 (50028320)
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| Co-Investigator(Kenkyū-buntansha) |
KASAI Chihiro Director, Research Laboratory, ALOKA Co., Ltd., 研究所, 所長
IZUMI Shiro Researcher, National Cardiovascular Center Research Institute, 研究所・循環動態機能部, 室員 (50159795)
MIYATAKE Kunio Senior Physician, National Cardiovascular Center Hospital, 病院, 医長
木下 直和 国立循環器病センター, 病院, 医長
榊原 博 国立循環器病センター, 病院, 副院長
SAKAKIBARA Hiroshi Vice-Director, National Cardiovascular Center Hospital
KINOSHITA Naokazu Senior Physician, National Cardiovascular Center Hospital
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| Project Period (FY) |
1984 – 1986
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| Project Status |
Completed (Fiscal Year 1986)
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| Budget Amount *help |
¥9,600,000 (Direct Cost: ¥9,600,000)
Fiscal Year 1986: ¥1,400,000 (Direct Cost: ¥1,400,000)
Fiscal Year 1985: ¥1,400,000 (Direct Cost: ¥1,400,000)
Fiscal Year 1984: ¥6,800,000 (Direct Cost: ¥6,800,000)
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| Keywords | Doppler flow image processing / ドプラ血流映像装置 / 血流映像処理装置 / リアル・タイム・ドプラ血流映像 / 弁逆流 |
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| Research Abstract |
An attempt was made to construct a new equipment for Doppler flow image processing so that quantitative data were obtained for intracardiac hemodynamics on the basis of the Doppler flow image on the screen of a commercially available real-time Doppler flow imaging system.
The colored Doppler flow image was feeded into the memory of the new equipment through an AD convertor. The new equipment was designed to obtain automatically quantitative hemodynamic data from the image data in the memory as follows : (1) determination of the velocity profile of blood flow in the cardiac chamber. The mitral rapid inflow exhibited a flat velocity profile, while the flow velocity was higher in the septal side than in the mitral leaflet side for the ejection flow through the left ventricular outflow tract; (2) determination of the profile of flow turbulence of blood flow in the cardiac chamber. It was demonstrated that the flow tubulence was enhanced at the time of acceleration and deceleration in the mi
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tral inflow and the ejection flow; (3) calculation of the area and volume occupied by the flow signals of valve regurgitation in the flow image. In this case, it was necessary to improve the image quality by smoothing and some other data-processing techniques. After that the range covered by the regurgitant flow signals were automatically recognized, so that its area was calculated. The volume of the regurgitant signal range was also calculated on the basis of the principle of Simpson's method; (4) analysis of shunt flow in congenital heart diseases. For example, distribution of flow velocity and that of flow turbulence were two-dimensionally observed in the left-to-right shunt flow of atrial septal defect. Flow velocity and turbulence index were obtained in digital form for each point in the shunt flow.
In the present new equipment, it took too long time for transfering data from the Doppler flow imaging system to the memory, so that it was impossible to obtain digital data in real-time. Alising in the Doppler system was not canceled in the present new equipment. These problems remain to be solved in future. Less
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