Development of bioglass coated titanium implant

• Project/Area Number: 59870062
• Research Category: Grant-in-Aid for Developmental Scientific Research
• Allocation Type: Single-year Grants
• Research Field: 補綴理工系歯学
• Research Institution: HIROSHIMA UNIVERSITY
• Principal Investigator: TSURU Hiromichi Hiroshima University School of Dentistry, 歯学部, 教授 (90034157)
• Co-Investigator(Kenkyū-buntansha): KONDO Noriaki Hiroshima University School of Dentistry, 歯学部, 助手 (20162109) ; AKAGAWA Yasumasa Hiroshima University Hospital, 歯学部附属病院, 講師 (00127599) ; NAGASAWA Tooru Hiroshima University School of Dentistry, 歯学部, 助教授 (20034168)
• Project Period (FY): 1984 – 1986
• Project Status: Completed (Fiscal Year 1986)
• Budget Amount: ¥8,800,000 (Direct Cost: ¥8,800,000); Fiscal Year 1986: ¥600,000 (Direct Cost: ¥600,000); Fiscal Year 1985: ¥1,400,000 (Direct Cost: ¥1,400,000); Fiscal Year 1984: ¥6,800,000 (Direct Cost: ¥6,800,000)
• Keywords: implant / ceramic / bioglass / 病理組織

Research Abstract

To examine a possibility of clinical use of the hybrid material (Ti6Al4V with Bioglass coating) for endosseous dental implant, two experiments were performed using Japanese monkeys.
(1) Initial bone healing was compared histologically between two implants. There were inserted into edentulous areas of both sides of the mandible, one by tapping and the other by non-tapping methods. Both implants were covered with a muco-periosteal flap of full thickness and allowed to heal for 3 months. All bioglass-coated implants, which ever the insertion method was, showed good healing with direct bone apposition, where as the controls without bioglass coating revealed various amonts of fibrousconnective tissue between bone and implant.
(2) Bioglass implants were inserted into the mandible by non-tapping method and loaded with functional stress by means of the superstructure. After 3, 6 and 9 months of function, histological specimens were prepare. Directory bone-implant interface was obviously achived in most regions along the outline of screw-saped implants.

Research Products

• [Publications] 里見圭一,池田隆彦,貝出泰範,富田秀伸,福岡賢二,浮田直人,永金幸治,前田希,佐藤裕二,橋本正毅,赤川安正,津留宏道: 日本歯科インプラント学会誌. 7. 150 (1986)
  • Description: 「研究成果報告書概要(和文)」より
• [Publications] 里見圭一,赤川安正,二階宏昌,津留宏道: 広島大学歯学雑誌. 19. (1987)
  • Description: 「研究成果報告書概要(和文)」より
• [Publications] 里見圭一,山田哲之,福岡賢二,前田希,石田栄作,高鳥忠彦,赤川安正,津留宏道: 日本補綴歯科学会雑誌. 31. (1987)
  • Description: 「研究成果報告書概要(和文)」より
• [Publications] Keiichi Satomi, Takahiko Ikeda, Yasunori Kaide, Hidenobu Tomita, Kenji Fukuoka, Naoto Ukita, Kouji Nagakane, Nozomu Maeda, Yuuji Sato, Masaki Hashimoto, Yasumasa Akagawa, Hiromichi Tsuru: "Experimental study on tissue structure surrounding submergible implans <II> Effects of implant materials and implant methods to bone tissues." Journal of Oral Implant Research. 7. 150 (1986)
  • Description: 「研究成果報告書概要(欧文)」より
• [Publications] Keiichi Satomi, Yasumasa Akagawa, Hiromasa Nikai, Hiromichi Tsuru: "Tissue reaction to endosseous hydroxyapatite coated titanium alloy implants. <II> . Reaction of bone tissue" The Journal of the Japan Prosthodontic Society. 19. (1987)
  • Description: 「研究成果報告書概要(欧文)」より
• [Publications] Keiichi Satomi, Tetsuyuki Yamada, Kenji Fukuoka, Nozomu Maeda, Eisaku Isida, Tadahiko Takatori, Yasumasa Akagawa, Hiromichi Tsuru: "Experimental study on hydroxyapatite coated endosseous implants" The Journal of the Japan Prosthodontic Society. 31. (1987)
  • Description: 「研究成果報告書概要(欧文)」より