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Molecular Biology of Paramyxoviruses and the Viral Pathogenesis

Research Project

Project/Area Number 60304053
Research Category

Grant-in-Aid for Co-operative Research (A)

Allocation TypeSingle-year Grants
Research Field Virology
Research InstitutionNagoya University

Principal Investigator

NAGAI Yoshiyuki  名古屋大学, 医学部, 教授 (20022874)

Co-Investigator(Kenkyū-buntansha) HOMMA Morio  神戸大学, 医学部, 教授 (10004566)
HOSAKA Yasuhiro  大阪大学, 微生物病研究所, 助教授 (50029766)
ITO Yasuhiko  三重大学, 医学部, 教授 (00022872)
YAMANOUCHI Kazuya  東京大学, 医科学研究所, 教授 (30072888)
SHIBUTA Hiroshi  東京大学, 医科学研究所, 教授 (70012721)
Project Period (FY) 1985 – 1987
Project Status Completed (Fiscal Year 1987)
Budget Amount *help
¥13,200,000 (Direct Cost: ¥13,200,000)
Fiscal Year 1987: ¥1,400,000 (Direct Cost: ¥1,400,000)
Fiscal Year 1986: ¥5,300,000 (Direct Cost: ¥5,300,000)
Fiscal Year 1985: ¥6,500,000 (Direct Cost: ¥6,500,000)
KeywordsParamyxovirus / Genome structure / Biosynthesis / Spread in hosts / Pathogenicity / 抗原性 / 遺伝子クローニング / 遺伝子一次構造 / モノクローン抗体 / 抗原性相関地図
Research Abstract

昭和62年度は本研究の最終年度にあたるため, 主として60, 61年度に得られた成果のとりまとめ, 公表に努力すると共に, 結果の総合的検討, 今後の展望の論議を行った. 本年度中に新たに得られた成果は, 各種パラミクソウイルスについての遺伝子構造の解析がさらに進んだこと, これをもとに, パラミクソウイルス全体の, あるいは特定のウイルス種における毒力の異なる株の進化についての解明が進んだこと, ウイルスの抗原決定基の形成に必要な構造が明らかになったこと, などがあげられる. 総合検討により, 本研究のような分子生物学と病理学が結合, 融合した新しいウイルス学の傾向がさらに大きく展開され, ウイルス病制御の新しい方法論の開拓へと結実することが強く期待されることを確認した.

Report

(3 results)
  • 1988 Annual Research Report
  • 1987 Final Research Report Summary
  • 1986 Annual Research Report
  • Research Products

    (187 results)

All Other

All Publications (187 results)

  • [Publications] Nishikawa,K.;Morishima,T.;Yoshida,T.;Hamaguchi,M.;Toyoda,T.;Nagai,Y.: Virus Res.7. 83-92 (1987)

    • Related Report
      1988 Annual Research Report
  • [Publications] Toyoda,T.;Hamaguchi,M.;Nagai,Y.: Arch.Virol.95. 97-110 (1987)

    • Related Report
      1988 Annual Research Report
  • [Publications] Toyoda,T.;Sakaguchi,T.;Imai,K.;Inocencio,N.M.;Gotoh,B.;Hamaguchi,M.;Nagai,Y.: Virology. 158. 242-247 (1987)

    • Related Report
      1988 Annual Research Report
  • [Publications] Gotoh,B.;Sakaguchi,T.;Nishikawa,K.;Inocencio,N.M.;Hamaguchi,M.;Toyoda,T.;Nagai,Y.: Virology. 163. (1988)

    • Related Report
      1988 Annual Research Report
  • [Publications] Shibuta,H.;Kanada,T.;Nozawa,A.;Sato,S.;Kumanishi,T.: Arch.Virol.83. 43-52 (1985)

    • Related Report
      1988 Annual Research Report
  • [Publications] Shioda,T.;Iwasaki,K.;Shibuta,H.: Nucleic Acids Res.14. 1545-1563 (1986)

    • Related Report
      1988 Annual Research Report
  • [Publications] Taira,H.;Kanda,T.;Omata,T.;Shibuta,H.;Kawakita,M.;Iwasaki,K.: J.Virol.61. 625-628 (1987)

    • Related Report
      1988 Annual Research Report
  • [Publications] Sakai,Y.;Suzu,S.;Shioda,T.;Shibuta,H.: Nucleic Acids Res.15. 2927-2944 (1987)

    • Related Report
      1988 Annual Research Report
  • [Publications] Suzu,S.;Sakai,Y.;Shioda,T.;Shibuta,H.: Nucleic Acids Res.15. 2945-2958 (1987)

    • Related Report
      1988 Annual Research Report
  • [Publications] Shioda,T.;Wakao,S.;Suzu,S.;Shibuta,H.: Virology. 162. 388-396 (1988)

    • Related Report
      1988 Annual Research Report
  • [Publications] Yoshikawa,Y.;Mizumoto,K.;Yamanouchi,K.: J.Gen.Virol.67. 2807-2812 (1986)

    • Related Report
      1988 Annual Research Report
  • [Publications] Tsukiyama,K.;Sugiyama,M.;Yoshikawa,Y.;Yamanouchi,K.: Virology. 160. 48-54 (1987)

    • Related Report
      1988 Annual Research Report
  • [Publications] Tsukiyama,K.;Yoshikawa,Y.;Yamanouchi,Y.: Virology. (1988)

    • Related Report
      1988 Annual Research Report
  • [Publications] Ito,Y.;Tsurudome,M.;Yamada,A.;Hishiyama,H.: J.Gen.Virol.68. 1261-1266 (1987)

    • Related Report
      1988 Annual Research Report
  • [Publications] Ito,Y.;Tsurudome,M.;Hishiyama,M.;Yamada,A.: J.Gen.Virol.68. 1289-1297 (1987)

    • Related Report
      1988 Annual Research Report
  • [Publications] Ito,Y.;Tsurudome,M.;Hishiyama,M.: Arch.Virol.95. 211-224 (1987)

    • Related Report
      1988 Annual Research Report
  • [Publications] Yokoo,J.;Miyadai,T.;Yokochi,T.;Kimura,Y.: Microbiol.Immunol.31. 139-146 (1987)

    • Related Report
      1988 Annual Research Report
  • [Publications] Kimura,Y.;Yokochi,T.;Miyadai,T.;Iwata,H.;Yokoo,J.;Matsumoto,K.: Cellular Immunology. 106. 287-292 (1987)

    • Related Report
      1988 Annual Research Report
  • [Publications] Cho,S.;Narahara,H.;Mifune,K.;Kawai,A.: J.Gen.Virol.68. 68. 1115-1123 (1987)

    • Related Report
      1988 Annual Research Report
  • [Publications] Xue-Ping,Gu;Ikeda,M.;Okahara,M.;Kim,J.: Chemistry Letters. 1715-1718 (1986)

    • Related Report
      1988 Annual Research Report
  • [Publications] Kim,J.;Okada,Y.: J.Membrane Biol.97. 241-249 (1987)

    • Related Report
      1988 Annual Research Report
  • [Publications] Itoh,M.;Shibuta,H.;Honma,M.: J.Gen.Virol.68. 2939-2943 (1987)

    • Related Report
      1988 Annual Research Report
  • [Publications] Yewdell,J.M.;Bennink,J.R.;Hosaka,Y.: Science. (1988)

    • Related Report
      1988 Annual Research Report
  • [Publications] Hosaka,Y.: Electron Micros.Reviews. (1988)

    • Related Report
      1988 Annual Research Report
  • [Publications] Nagai,Y.;Toyoda,T.: "Molecular biology of Newcastle disease virus,in Progress in Veterinary Microbiology and Immunology" Karger, inpress (1988)

    • Related Report
      1988 Annual Research Report
  • [Publications] 永井美之,西山幸廣: "医系微生物学" 朝倉書店, 9 (1987)

    • Related Report
      1988 Annual Research Report
  • [Publications] 永井美之: "医系微生物学" 朝倉書店, 3 (1987)

    • Related Report
      1988 Annual Research Report
  • [Publications] 永井美之: "図解微生物学ハンドブック" 丸善,

    • Related Report
      1988 Annual Research Report
  • [Publications] 木村吉延: "医系微生物学" 朝倉書店, 4 (1987)

    • Related Report
      1988 Annual Research Report
  • [Publications] 河合明彦: "ウイルス学" 理工学者, 15 (1987)

    • Related Report
      1988 Annual Research Report
  • [Publications] 吉田哲也: "医系微生物学" 朝倉書店, 3 (1987)

    • Related Report
      1988 Annual Research Report
  • [Publications] 吉田哲也: "エッセンシャル微生物学(第3版)"

    • Related Report
      1988 Annual Research Report
  • [Publications] 渋田博: "新基礎生化学実験法「第一巻生物材料の取扱い」" 医歯薬出版, 20 (1987)

    • Related Report
      1988 Annual Research Report
  • [Publications] hamaguchi,M.;Niahakawa,K.;Toyoda,T.;Yoshida,T.;Hanaichi,T,;and Nagai,Y.: Virology. 147. 295-308 (1985)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Naruse, H.;morishima, T,Isomura, S.; Hamaguchi,M.; Toyoda, T.; Yoshida,T.;and Nagai,Y.: Med. Microbiol. Immunol.174. 295-304 (1986)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Hanada,N.; Morishima, T;Nishikawa, K.; Isomura,S.;and Nagai, Y.: J. Med. Virol.20. 363-370 (1986)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Nishikawa,K.; Morishima,T.;Toyoda, T.;Miyadai, T.;Yolochi, Y.;yoshida,T.;and Nagai,Y.: J. Virol.60. 987-993 (1986)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Nishikawa,K.;Morishima,T.;Yoshuida,T.;Hamaguchi,M.;Toyoda, T.;and Nagai,Y.: Virus Res.7. 83-92 (1987)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Toyoda,T,; Hamaguchi, M.;and Nagai,y.: Arch. Virol.95. 97-110 (1987)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Toyoda, T.;Sakaguch,T.; Imai, K.;Inocencio,N.M.; Gotoh, B.; Hamaguchi,M.and Nagai,Y.: Virology. 158. 242-247 (1987)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Gotoh, B.; Sakaguchi, T.; Nishikawa,K.; Inocencio, N.M.; Hamaguchi,M.;Toyoda, T.and Nagai,Y.: @virology.

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Shybuta, H.; Kanda, T.;nozawa.A.; Sato, S. and Kumanishi, T.: Arch. Virol.83. 43-52 (1985)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Shioda, T.; Iwasaki, K. and Shibuta, H.: Nucleic Acids Res.14. 1545-1563 (1986)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Shibuta, H,; Suzu, s. and Shioda, T.: virology. 155. 688-696 (1986)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Taira, H.; Kanda, T.;Omata, T.f Shibuta, H.; Kawakita, M. and Iwasaki, K.: J.Virol.61. 625-628 (1987)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Sakai, Y.; Suzu; %s.; Shioda, T. and Shibuta, H.: Nucleic Acids Res.15. 2927-2944 (1987)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Suzu, S,; Sakai,; Shioda, T.and Shibuta, H.: Nucleic Acids Res.15. 2945-2958 (1987)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Shioda, T.; Wakao, S.f Suzu, S. and Shibuta, H.: Virology. 4162. 388-396 (1988)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Yoshikawa, Y.; Mizumoto, K. and Yamanouchi, K.: J.gen. Virol.67. 2807-2812 (1986)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Tsukiyama, K.; Sugiyama, M.; Yoshikawa, Y. and Yamanouchi,K.: Virology. 60. 48-54 (1987)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Yoshi: Encephalh′s; mosquntos and virus in Karachi.1. 1-10 (1988)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Tsukiyama, K.; Yoshikwa, Y.; and Yamanouchi,Y.: Virology. 1988.

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Tozawa, H.; Komatsu, H,; ohkata, o.; Nakajima, T.; Watanabe, M; Tanaka, Y.,and Arifuku, M.: Arch. Virol.91. 145-161 (1986)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Ito, Y.; Tsurudome, M.; and Hishiyama, M.: Microbiol. Immunol.847-857 (1985)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Ito, Y.; Tsurdome, M.; and Hishiyama, M.: Arch. Virol.88. 217-230 (1986)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Tsurudome, M.; Yamada, A.;Hishiyama, M.; and Ito, Y.: J. Gen. Virol.67. 2259-2265 (1986)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Ito, Y.; Tsurudome, 7.; Yamada, A.; and Hishiyama, H.: J. Gen. virol.68. 1261-1266 (1987)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Ito, Y.; Tsurudome, M.;Hishiyama, M.; and Yamada, A.: J. Gen. Virol.68. 1289-1297 (1987)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Uto, Y.; Tsurudome, M.; and Hishiyama, M.: @arch. Virol.95. 211-224 (1987)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Kimura, Y.; Yokochi, T.; Miyadai, T.; Yoshida, k.; Yokoo,j.; and Matsumoto, k.: J. Virol.53. 983-983 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Yokoo, J.; Miyadai, T.; Yokochi, T.; and Kimura, y.: Microbiol. Immunol.1. 139-146 (1987)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Kimura, Y.; Yokochi, T.;Miyadai, T.; Iwata, H.; Yokoo, 4.; and Matsumoto, K.: Cellular Immunology. 106. 287-292 (1987)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Honda, Y.; Kawai, A.; and Matumoto, S.: J. Gen. Virol.66. 957-967 (1985)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Cho, S.; Narahara, H.; Mifune, K.; and Kawai,A.: J. Gen. Virol. 68. 68. 1115-1123 (1987)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Xue-Ping Gu; Ikeda, M.; Okahara, M.; and Kim, J.: Chemistry Letters. 1715-1718 (1986)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Kim, J.; and Okada, Y.: J. Membrane Biol.97. 241-249 (1987)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Hosaka, y.; Yasuda, Y.; Seriburi, O., Moran, M.O., and Fukai, K.: J. virol.57. 1113-1118 (4986)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Yewell, J.M.; Bennink, J. R.; and Hosaka, Y. iCells process exogenous proteins for recognition by cytotoxic: Sciencs. (1988)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] uHosaka, Y.: Electron Micros. Revies. (1988)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Cho, S.,Narahara, H.;Mufune, K.;and Kawai,A.: J.Gen.Virol.68. 68. 1115-1123 (1987)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Xue-Ping Gu; Ikeda, M.;Okahara,M.;and Kim,J.: Chemistry Letters. 1715-1718 (1986)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Kim, J.; and Okada, Y.: J. Membrane @biol.97. 241-249 (1987)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Hosaka, Y.;Yasuda, Y.; seriburi,O.; Moran, M. O., and Fukai, K.: J.Virol.57. 1113-1118 (1986)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Yewdell;J.M.;Bennink,J.R.;and Hosaka, Y.: Science. (1988)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Hosaka, Y.: Electron Micros. Reviews. (1988)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Homa, M.: Asaian Medical Joural. 28. 137-147 (1985)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Tashiro, M.; and Homma, M.: J. Virol.53. 228-234 (1985)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Ohara, Y.;Tashiro, M.;Takase, S.; and Homma, M.: Microbiol. Immunol.29. 709-723 (1985)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Itoh, M.; Shibuta, H.; and Homma, M.: J.Gen. Virol.68. 2939-2943 (1987)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Yoshida, T.; Nakayama, Y.; Toyoda T.; Nishikawa, K.; Hamaguchi, M.; and Nagai, y.: Microbiol. Immunol.29. 577-582 (1985)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Kamihira, O.; Nakashima, I.; Hasegawa, T.; Ando, K.; isobe,K.; Nagase, F.; Hasegawa, Y.;Yoshda.T.; Kawashima, K.; Yoshida, T.; and Yokochi, Y.: Immunology Letters. 11. 75-81 (1985)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Yashida, T.;Nakayama, Y.; Nagura, H.; Toyoda, @.;Nishikawa, K.; Hamaguchi, M.; and Nagai, y: Virus Research. 4. 179-195 (1986)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Nagai, y.; and Toyoda. T.: "Molecular biology of Newcastle disease virus, in Progress in Veterinary Microbiology and Immunology." iKarger, IN PRESS (1988)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] 水井美之,西山幸廣: "医糸微生物学" 朝倉書店, 9 (1987)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] 永井美之: "医系微生物学" 朝倉書店, 3 (198)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] 永井美之: "図解微生物学ハンドブック" 丸善,

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] 渋田 博: "新基礎生化学実験法『第一巻生物材料の取扱い』" 医歯薬出版, 20 (1987)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] 山内一也: "実験動物感染病学" ソフトサイエンス社, 22 (1986)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] 木村吉延: "医系微生物学" 朝倉書店, 4 (1987)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] 河合明彦: "ウィルス学" 理工学者, 15 (1987)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] 保坂康弘: "最新医学教育講座.電子顕微鏡研究法の基本的実検" 卒後教育学術情報センター, 1 (1986)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] 保坂康弘: "電子顕微鏡診断-基礎と実際-" 藤田企画出版, 21 (1986)

    • Description
      「研究成果報告書概要(和文)」より
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      1987 Final Research Report Summary
  • [Publications] 松本慶蔵.本間守男: "グラワドウォール臨床検査学.第4巻微物生物学" 医歯薬出版, 1069 (1985)

    • Description
      「研究成果報告書概要(和文)」より
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      1987 Final Research Report Summary
  • [Publications] Homma,M A.L.Notkins & M.B.A.old-stone: "Concepts in Viral Puthogenesis" Springer, 12 (1986)

    • Description
      「研究成果報告書概要(和文)」より
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      1987 Final Research Report Summary
  • [Publications] 吉田哲也: "医系微生物" 朝倉書店, 3 (1987)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] 吉田哲也: "エッセンシャル微生物学(第3版)"

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Hamaguchi, M., Nishikawa, K., Toyoda, T., Yoshida, T., Hanaichi, T., and Nagai, Y.: "Transcriptive complex of Newcastle disease virus. II. Structural and functional assembly associated with the cyloskeletal framework." virology. 147. 295-308 (1985)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Naruse, Y., Morishima, T., Isomura. S., Hamaguchi, M., Toyoka, T., Yoshida, T., and Nagai, Y.: "Studies on the adaptation of mumps virus to chick embryo. Med. Microbiol." Immunol.174. 295-304 (1986)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Hanada, N., Morishima, T., Nishikawa, K., Isomura. S., and Nagai, Y.: "Interferon-mediated self-limiting growth of respiratory syncytial virus in mouse embryo cells." J. Med. Virol.20. 363-370 (1986)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Nishikawa, K., Morishima, T., Toyada, T., Miyadai, T., Yokochi, Y., Yoshida, T., and Nagai, Y.: "Topological and functional delineation of antigenic sites on the HN glycoprotein of Newcastle disease virus and their structural requirements" J. Virol. 60. 987-993 (1986)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Nishikawa, K., Morishima, T., Yoshida, T., Hamaguchi, M., Toyoda, T.,and Nagai, Y.: "Antigenic Characterization of the internal proteins of Newcastle disease virus by monoclonal antibodies" Virus. Res.7. 83-92 (1987)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Toyoda, T., Hamaguchi, M., and Nagai, Y.: "Detection of polycistronic transcripts in Newcastle disease virus infected cells and identification of thier sequence content." Arch. Virol.95. 97-110 (1987)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Toyoda, T.,Sakaguchi, T., Imai, K., Inocencio, N. M., Gotoh, B., Hamaguchi, M., and Nagai, Y.: "Structural comparison of the cleavage-activation site of the fusion glycoprotein between virulent and avirulent strains of Newcastle disease virus" Virology. 158. 242-247 (1987)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Gotoh, B., Sakaguchi, T., Nishikawa, K., Inocencio, N. M. Hamaguchi, M., Toyoda, T., and Nagai. Y.: "Structural features unique to each of the three antigenic sites on the hemagglutinin-neuraminidase protein of Newcastle disease virus." Virology.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Shibuta, H., Kanda. T., Nozawa, A., Sato, S., and Kumanishi, T.: "Experimental parainfluenza virus infection in mice: growth and spread of a highly pathogenic variant of parainfluenza 3 virus in the mouse brain" Arch. Virol.83. 43-52 (1985)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Shioda, T., Iwasaki, K., and Shibuta, H.: "Determination of the complete nucleotide sequence of the Sendai virus genome RNA and the predicted amino acid sequences of the F, HN and L proteins." Nucleic Acids Res.14. 1545-1563 (1986)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Shibuta, H., Suzu, S., and Shioda, T.: "Differences in bovine parainfluenza 3 virus variants studied by monoclonal antibodies against viral glycoproteins" Virology. 155. 688-696 (1986)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Taira, H., Kanda, T., Omata, T., Shibuta, H., Kawakita, M., and Iwasaki, K.: "Interferon induction by transfection of Sendai virus C gene cDNA." J. Virol.61. 625-628 (1987)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Sakai, Y., Suzu, S., Shioda, T., and Shibuta, H.: "Nucleotide sequence of the bovine Paratinfluenza 3 virus genome: its 3 end and the genes of NP, P, C and M proteins" Nucleic Acids Res.15. 2927-2944 (1987)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Suzu, S., Sakai, Y., Shioda, T., and Shibuta, H.: "Nucleotide sequence of the bovine parainfluenza 3 virus genome: the genes of the F and HN glycoproteins" Nucleic Acids Res.15. 2945-2958 (1987)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Shioda, T., Wakao, S., Suzu, S., and Shibuta, H.: "Differences in bovine parainfluenza 3 virus variants studied by sequencing of the viral envelope proteins." virology. 162. 162 (1988)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Yoshikawa, Y., Mizumoto, K., and Yamanouchi, K.: "Characterization of messenger RNAs of measles virus" J. Gen. Virol.67. 2807-2812 (1986)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Tsukiyama, K., Sugiyama, M., Yoshikawa Y., and Yamanouchi K.: "Molecular Cloning and Sequence analysis of the Rinderpest virus mRNA encoding the hemagglutinin protein." Virology. 160. 48-54 (1987)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Yoshikawa, Y., Tsuruoka, H., Yamanouchi, K., Shioda, T., and Shibuta, H.: "Cloning and sequencing of a cDNA corresponding to the P plus M dicistronic mRNA of an SSPE virus." Encephalihihis, mosquitos and vivuo in karachi,. P1-10 (1987)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Tsukiyama, K., Yoshikawa, Y., and Yamanouchi, Y.: "Fusion glycoprotein (F) of rinderpest virus: Entire nucleotide sequence of the F mRNA and several features of the F protein." Viorology.

    • Description
      「研究成果報告書概要(欧文)」より
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      1987 Final Research Report Summary
  • [Publications] Tozawa, H., Komatsu, H., Ohkata, O., Nakajima, T., Watanabe, M., Tanaka, Y. and Arifuku, M.: "Neutralizing Activity of the antibodies against two kinds of envelope glycoproteins of Sendai virus." Arch. Virol.91. 145-161 (1986)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Ito, Y., Tsurudome, M., and Hishiyama, M.: "Persistence of mumps virus in mouse L929 cells." Microbiol. Immunol.29. 847-857 (1985)

    • Description
      「研究成果報告書概要(欧文)」より
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      1987 Final Research Report Summary
  • [Publications] Ito, Y., Tsurudome, M., And Hishiyama, M.: "Effects of antibodies and interferon on mumps virus persistently infected L929 cells." Arch. Virol.88. 217-230 (1986)

    • Description
      「研究成果報告書概要(欧文)」より
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      1987 Final Research Report Summary
  • [Publications] Tsurudome, M., Yamada, A., Hishiyama, M., ad Ito, Y.: "Monoclonal antibodies against the glycoproteins of mumps virus: Fusion inhibition by anti-HN monoelonal antibody." J. Gen. Virol.67. 2259-2265 (1986)

    • Description
      「研究成果報告書概要(欧文)」より
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      1987 Final Research Report Summary
  • [Publications] Ito, Y., Tsurudome, M., Yamada. A., and Hishiyama, M.: "Induction of cell fusion in Newcastle disease virus-infected L929 cells by anti-L929 cell anti sera." J. Gen. Virol.68. 1261-1266 (1987)

    • Description
      「研究成果報告書概要(欧文)」より
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      1987 Final Research Report Summary
  • [Publications] Ito, Y., Tsurudome, M., Hishiyama. M., and Yamada, A.: "Immunological interrelationsgips among human and non-human paramyxoviruses revealed by immunoprecipitation." J. Gen. Virol.68. 1289-1297 (1987)

    • Description
      「研究成果報告書概要(欧文)」より
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      1987 Final Research Report Summary
  • [Publications] Ito, Y., Tsurudome, M., and Hishiyama, M.: "The polypeptides of human parainfluenza type 2 virus and their synthesis in infected cells." Arch. Virol.95. 211-224 (1987)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Kimura, Y., Yokochi, T., Miyadai, T., Yoshida, K., Yokoo, J., and Matsumoto, K.: "Characterization of a porcine kidney cell line resistant to influenza virus infection." J. Virol.53. 980-983 (1985)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Yokoo, J., Miyakai, T., Yokochi, T., and kimura, Y.: "Effect of cytolytic infection on maintenance of resistance to HVJ (Sendai virus) in an altered BHK cell culture." Microbiol. Immunol.31. 139-146 (1987)

    • Description
      「研究成果報告書概要(欧文)」より
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      1987 Final Research Report Summary
  • [Publications] Kimura Y., Yokochi, T., Miyadai, T., Iwata, H., Yokoo, J., and Matsumoto, K.: "Reversible susceptibility to natural cell-mediated cytotoxicity boserved in altered BHK cells resistant to HVJ (Sendai virus) infection." Cellular Immunology. 106. 287-292 (1987)

    • Description
      「研究成果報告書概要(欧文)」より
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      1987 Final Research Report Summary
  • [Publications] Honda, Y., Kawai, A., and Matsumoto, S.: "Persistent infection of rabies virus (HEP-flury strain) in human neuroblastoma cells capable of producing interferon." J. Gen. Virol.66. 957-967 (1985)

    • Description
      「研究成果報告書概要(欧文)」より
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      1987 Final Research Report Summary
  • [Publications] Cho, S., Narachara, H., Mifune, K., and Kawai, A.: "Murine T cell clones directed to rabies virus: Isolation and some of their properties." J. Gen. Virol.68. 1115-1123 (1987)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Xue-Ping Gu, Ikeda, M., Okahara, M., and Kim, J.: "Synthesis of 3,5-Bis (2,5,8,-trioxaeicosyl)-18-crown 6 and its formation of bilayer membrane." Chemistry Letters. 1715-1718 (1986)

    • Description
      「研究成果報告書概要(欧文)」より
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      1987 Final Research Report Summary
  • [Publications] Kim, J., and Okada, Y.: "Difference in capacities for virion-to-virion fusion of young and aged HVJ (Sendai virus): A model of membrane fusion." J. Membrane Biol.97. 241-249 (1987)

    • Description
      「研究成果報告書概要(欧文)」より
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      1987 Final Research Report Summary
  • [Publications] Hosaka, Y., Yasuda, Y., Seriburi, O., Moran, M. O., and Fukai, K.: "In vitro secondary generation of cytotoxic T lymphocytes in mouse with mumps virus and thier mumps-specific cytotoxicity among paramyxoviruses." J. Virol.57. 1113-1118 (1986)

    • Description
      「研究成果報告書概要(欧文)」より
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      1987 Final Research Report Summary
  • [Publications] Yewdell, J. M., Bennink, J. R., and Hosaka, Y.: "Cells process exogenous proteins for recognition by cytotoxic T lymphocytes." Science. (1988)

    • Description
      「研究成果報告書概要(欧文)」より
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      1987 Final Research Report Summary
  • [Publications] Hosaka, Y.: "Sendai virion structure and its interaction with cellular membranes." Electron Micros.Reviews 1.

    • Description
      「研究成果報告書概要(欧文)」より
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      1987 Final Research Report Summary
  • [Publications] Homma, M.: "Pneumotropism of Sendai virus (HVJ) in mice in relation to activation of the progeny virus in the lung." Asian Medical Journal. 28. 137-147 (1985)

    • Description
      「研究成果報告書概要(欧文)」より
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      1987 Final Research Report Summary
  • [Publications] Tashiro, M., and Homma, M.: "Protection of mice from wild-type Sendai virus infections by a trypsin-rosistant mutant, TR-2." J. Virol.53. 228-234 (1985)

    • Description
      「研究成果報告書概要(欧文)」より
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      1987 Final Research Report Summary
  • [Publications] Ohara, Y., Tashiro, M., Takase, S., and Homma, M.: "Delection of antibody to M protein of measles virus in patients with subacutesclerosing panecephalitis: A comparative study on Immuno-precipitation." Microbiol. Immunol.29. 709-723 (1985)

    • Description
      「研究成果報告書概要(欧文)」より
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      1987 Final Research Report Summary
  • [Publications] Itoh, M., Shibuta, H., and Homma, M.: "Single amino acid substitution of Sendai virus at the cleavage site of the fusion protein confers trypsin resistance." J. Gen. Virol.68. 2939-2943 (1987)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Yoshida, T., Nakayama, Y. Toyoda, T., Nishikawa, K.,: "Hamaguchi, M., and Nagai, Y. The polypeptides of human parainfluenza 1 (HA-2) virus and thier antigenic relationships to those of Sendai virus (HVJ)." Microbiol. Immunol.29. 577-582 (1985)

    • Description
      「研究成果報告書概要(欧文)」より
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      1987 Final Research Report Summary
  • [Publications] Kamihira, O., Nakashima, I., Hasegawa, T., Ando, K., Isobe, K., Nagase, F., Nasegawa, Y., Yoshida, T., Kawashima, K., Yoshida, T., and Yokochi, Y.: "Direct activation of Sendai virus (HVJ)-specific cell-mediated immunity ofmice for second set rejection of the virus-infected syngeneic tumor by noninfections virus-sensitized spleen cells." Immunology Letters. 11. 75-81 (1985)

    • Description
      「研究成果報告書概要(欧文)」より
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      1987 Final Research Report Summary
  • [Publications] Yoshida, T., Nakayama, Nagura, H., Toyoda, t., Nishikawa, K., Hamaguchi, M., and Nagai, Y.: "Inhibition of the assembly of Newcastle disease virus by monensin." Virus Research. 4. 179-195 (1986)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Y. Nagai.: Molecular biology of Newcastle disease virus. Progress in Veterinary Microbiology and lmmunology, Vol. 5,. Karger, (1988)

    • Description
      「研究成果報告書概要(欧文)」より
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      1987 Final Research Report Summary
  • [Publications] Y. Nagai, and Y. Nishiyama: Medical Microbiology. Asakurashoten, 251-259 (1982)

    • Description
      「研究成果報告書概要(欧文)」より
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      1987 Final Research Report Summary
  • [Publications] Y. Nagai: Medical Microbiology. Asakurashoten, 295-297 (1982)

    • Description
      「研究成果報告書概要(欧文)」より
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      1987 Final Research Report Summary
  • [Publications] Y. Nagai: Microbiology handbook. Maruzen, (1988)

    • Description
      「研究成果報告書概要(欧文)」より
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      1987 Final Research Report Summary
  • [Publications] H. Shibuta: New Methods in Biochemistry, Vol. 1. Maruzen, 223-242 (1987)

    • Description
      「研究成果報告書概要(欧文)」より
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      1987 Final Research Report Summary
  • [Publications] K. Yamanouchi: Infection Pathology of Animals. Soft science Co., (1985)

    • Description
      「研究成果報告書概要(欧文)」より
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      1987 Final Research Report Summary
  • [Publications] Y. Kimura: Medical Microbiology. Asakurashoten, 259-262 (1987)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] A. Kawai: Virology. Rikogakusha, 369-382 (1987)

    • Description
      「研究成果報告書概要(欧文)」より
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      1987 Final Research Report Summary
  • [Publications] Y. Hosaka: Basic Methods for Electron Microscopy. Post graduate education center, 163 (1986)

    • Description
      「研究成果報告書概要(欧文)」より
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      1987 Final Research Report Summary
  • [Publications] Y. Hosaka: Diagnosis by Electron Microscopy. Fujita shuppan, 320 (1986)

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      「研究成果報告書概要(欧文)」より
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      1987 Final Research Report Summary
  • [Publications] K. Matsumoto, and M. Homma: Gradwall Laboratory Medicine, Vol.4. Ishiyaku syuppan, 1-1069 (1985)

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      「研究成果報告書概要(欧文)」より
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      1987 Final Research Report Summary
  • [Publications] A. L. Notkins, M. B. A. Oldstone, eds M. Homma: Concepts in Viral Psthogenesis II. Springer-Verlag, New York, 388-393 (1986)

    • Description
      「研究成果報告書概要(欧文)」より
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      1987 Final Research Report Summary
  • [Publications] T. Yoshida: Essential Microbiology, Vol. 3. Ishiyaku shuppan, (1988)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] T. Yoshida: Medical Microbiology. Asakura shoten, 262-266 (1987)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] Shioda,T.: Nucleic Acid Res.14. 1545-1563 (1986)

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      1986 Annual Research Report
  • [Publications] Shibuta,H.: Virology. 155. 688-696 (1986)

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      1986 Annual Research Report
  • [Publications] Sakai,Y.: Nucleic Acid Res.(1987)

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      1986 Annual Research Report
  • [Publications] Suzu,F.: Nucleic Acid Res.(1987)

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      1986 Annual Research Report
  • [Publications] Toyoda,T.: Virology. 157. (1987)

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      1986 Annual Research Report
  • [Publications] Sakaguchi,T.: Submitted to Virology.

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      1986 Annual Research Report
  • [Publications] Nishikawa,K.: J.Virol.60. 987-993 (1986)

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      1986 Annual Research Report
  • [Publications] Toyoda,T.: Arch.Virol.

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      1986 Annual Research Report
  • [Publications] Nishikawa,K.;Hanada,N.;Morishima,T.;Yoshida,T.;Hamaguchi,M.and Nagai,Y.: Virus Res.7. 83-92 (1987)

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      1986 Annual Research Report
  • [Publications] Hanada,N.: J.Med.Virol.20. 363-370 (1986)

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      1986 Annual Research Report
  • [Publications] Tozawa,H.: Arch.Virol.91. 145-161 (1986)

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      1986 Annual Research Report
  • [Publications] Morikawa,Y.: Microbiol.Immunol.30. 225-236 (1986)

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      1986 Annual Research Report
  • [Publications] Ishii,H.: J.gen.Virol.67. 275-280 (1986)

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      1986 Annual Research Report
  • [Publications] Sakaguchi,M.: Jap.J.Exp.Med.56. 61-67 (1986)

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      1986 Annual Research Report
  • [Publications] Hirayama,N.: Jap.J.Vet.Sci.48. 259-265 (1986)

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      1986 Annual Research Report
  • [Publications] Yoshikawa,Y.: J.gen.Virol.67. 2807-2812 (1986)

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      1986 Annual Research Report
  • [Publications] Sata,K.: Virchows Archiv A. 410. 133-138 (1986)

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      1986 Annual Research Report
  • [Publications] Kimura,Y.: Cellular Immunology. in press. (1987)

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      1986 Annual Research Report
  • [Publications] Yokoo,J.: Microbiol.Immunol.(1987)

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      1986 Annual Research Report
  • [Publications] Matsumoto,K.: Microbiol.Immunol.30. 935-938 (1986)

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      1986 Annual Research Report
  • [Publications] Matsumoto,K.: Microbiol.Immunol.30. 333-342 (1986)

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      1986 Annual Research Report
  • [Publications] Yokochi,T.: Virology. 148. 114-120 (1986)

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  • [Publications] Tsurudome,M.: J.gen.Virol.67. 2259-2265 (1986)

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      1986 Annual Research Report
  • [Publications] Ito,Y.: J.gen.Virol.(1987)

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      1986 Annual Research Report
  • [Publications] Ito,Y.: J.gen.Virol.(1987)

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      1986 Annual Research Report
  • [Publications] Ito,Y.: Arch.Virol.(1987)

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      1986 Annual Research Report
  • [Publications] Hernandes,F.: J.Virological Methods. (1987)

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      1986 Annual Research Report
  • [Publications] Kim,J.: J.Memb.Biol.

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      1986 Annual Research Report
  • [Publications] Itoh,M.: J.gen.Virol.

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      1986 Annual Research Report
  • [Publications] Nagai,Y.: "Paramyxovirus metabolisms associated with the cytoskeletal framework,in"Modern Trends in Virology"" H.-D.Klenk,C.Scholtissek and H.Bauer eds.Springer Verlag, (1987)

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      1986 Annual Research Report
  • [Publications] Nagai,Y.: "Molecular biology of Newcastle disease virus,in Progress in Veterinary Microbiology and Immunology"" R.Pandey ed.Karger., (1987)

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      1986 Annual Research Report
  • [Publications] Homma,M.: "Cleavage site mutant as a potential vaccine,in"Concepts in Viral Pathogenesis"." A.L.Notkins,and M.B.A.Oldstone,eds.Springer-Verlag., 425 (1986)

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      1986 Annual Research Report
  • [Publications] Hosaka,Y.: "Electron Microscopy Reviews:Subcellular and Biomolecular Structure(Chapter:Sendai virus)." Pergamon Journals Ltd., 40 (1987)

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      1986 Annual Research Report
  • [Publications] 保坂康弘: "ウイルスの微細構造(電子顕微鏡診断学-基礎と実際-)" 藤田企画出版株式会社, 21 (1986)

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      1986 Annual Research Report

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