• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Clinical Studies on Radiation Tolerance Doses

Research Project

Project/Area Number 60304062
Research Category

Grant-in-Aid for Co-operative Research (A)

Allocation TypeSingle-year Grants
Research Field Radiation science
Research InstitutionKyushu University

Principal Investigator

MATSUURA Keiichi  Kyushu University, Honorary Professor, 医学部, 教授 (30037410)

Co-Investigator(Kenkyū-buntansha) MORITA Kozo  Aichi Cancer Center, Chief of Dept. Radiotherapy, 放射線治療部, 部長 (50182241)
HORIUCHI Junichi  Tokyo Medical & Dental University, Medical School Assistant Professor, 医学部・放射線科, 助教授 (90013870)
MOCHIZUKI Sachio  Jikei University, School of Medicine, Professor, 放射線科, 教授 (10056533)
KANETA Koichi  Gankenkyuukai Hospital, Director, 放射線治療部, 部長 (70085603)
桜井 智康  国立札幌病院, 放射線科, 医長
SAKURAI Tomoyasu  National Sapporo Hospital, Head of Dept. Radiology
Project Period (FY) 1985 – 1986
Project Status Completed (Fiscal Year 1986)
Budget Amount *help
¥5,800,000 (Direct Cost: ¥5,800,000)
Fiscal Year 1986: ¥2,500,000 (Direct Cost: ¥2,500,000)
Fiscal Year 1985: ¥3,300,000 (Direct Cost: ¥3,300,000)
KeywordsRadiation Tolerance Dose / 放射線治療
Research Abstract

An attempt has been made to estimate the radiation tolerance doses for various organs on analysis of dose response plots, using data obtained from many institutes in Japan. The limits of tolerance is a clinical concept. The difinition of the tolerance and the observation period which is necessary to estimate the persentage for the risk of complication, are dependent on the severity of primary malignant tumor. And this study was retrospective one. Therefore, a sufficient number of data was not obtained to estimate the tolerance doses and time-dose relationships for all kind of normal tissues.
Utilizing the standard set of conditions of current-day treatment in many institutes, the tolerance levels for several normal tissues were estimated : the tolerance dose for eye was larger than that reported by Rubin & Casarett, while those for oral mucosa, skin and blase was as large as those reported by Rubin & Casarett ; the tolerance of thyroid, estimated using hypothyroidism as an end point, was smaller than that reported by Rubin & Casarett.

Report

(1 results)
  • 1986 Final Research Report Summary
  • Research Products

    (10 results)

All Other

All Publications (10 results)

  • [Publications] 森田皓三: 癌の臨床. 33. (1987)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1986 Final Research Report Summary
  • [Publications] 堀内淳一: 癌の臨床. 32. 117-122 (1986)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1986 Final Research Report Summary
  • [Publications] 堀内淳一: 癌と化学療法. 13. 1717-1724 (1986)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1986 Final Research Report Summary
  • [Publications] 堀内淳一: 臨床放射線. 31. 1435-1440 (1986)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1986 Final Research Report Summary
  • [Publications] 堀内淳一: "放射線医学大系NO.31" 中山書店, 64 (1987)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1986 Final Research Report Summary
  • [Publications] Kozo Morita: "Application of the life table method to estimation of the late complications of the normal tissues after radiotherapy" Jap. J. Cancer Clin.33. (1987)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1986 Final Research Report Summary
  • [Publications] Junichi Horiuchi, M. D.: "Results of Radiation therapy for Carcinoma of the salivary Glands" Jap. J. Cancer Clin.32. 117-122 (1986)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1986 Final Research Report Summary
  • [Publications] Junichi Horiuchi, M. D.: "Role of Radiation therapy in the Multi-modal Treatment of Head and Neck Cancer. - With Special emphasis on Oral and Maxillary Sinus Cancer -" Jpn. J. Cancer Chemother.13(4). 1717-1724 (1986)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1986 Final Research Report Summary
  • [Publications] Junichi Horiuchi, M. D.: "Clinical Evaluation of After-loading Ir-192 Source on the Treatment of Tongue Cancer" Jpn. J. Clin. Radiol.31(12). 1435-1440 (1986)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1986 Final Research Report Summary
  • [Publications] Junichi Horiuchi, M. D.: Nakayama Shoten. Carcinoma of Oral Cavity (in Encyclopedia of Clinical Radiology), 63-127 (1987)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1986 Final Research Report Summary

URL: 

Published: 1987-03-31   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi