| Project/Area Number |
60304076
|
|---|
| Research Category |
Grant-in-Aid for Co-operative Research (A)
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Conservative dentistry
|
|---|
| Research Institution | Niigata University |
|---|
Principal Investigator |
HARA Kohji Niigata University School of Dentistry Professor, 歯学部, 教授 (20018419)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
UENO Kazuyuki Iwate Medical University School of Dentistry Professor, 歯学部, 教授 (00048307)
SUEDA Takeshi Kagoshima University School of Dentistry Professor, 歯学部, 教授 (30013890)
ISHIKAWA Isao Tokyo Medical and Dental University School of Dentistry Professor, 歯学部, 教授 (10014151)
IWAYAMA Yukio Asahi University School of Dentistry Professor, 歯学部, 教授 (70028744)
NIKAI Hiromasa Hiroshima University School of Dentistry Professor, 歯学部, 教授 (60028735)
|
|---|
| Project Period (FY) |
1985 – 1986
|
| Project Status |
Completed (Fiscal Year 1986)
|
| Budget Amount *help |
¥9,300,000 (Direct Cost: ¥9,300,000)
Fiscal Year 1986: ¥3,000,000 (Direct Cost: ¥3,000,000)
Fiscal Year 1985: ¥6,300,000 (Direct Cost: ¥6,300,000)
|
|---|
| Keywords | Junctional epithelium / Keratin antibody / Gingival crevicular fluid / Fibroblast / Vertical alveolar defect / Bioglass / <beta> -tricalcium phosphate / 遊離歯肉移植 |
|---|
| Research Abstract |
The process of initial periodontal destruction, especially morphologic changes in junctional epithelium associated with pocket formation was observed microscopically (Nikai). Uptake of monoclonal keratin antibody into human inflamed gingiva and oral mucosa in various animals was detected (Mori). Function of PMN leukocytes in circulatory blood of healthy person was examined using immunological techniques (Ikeda). Uptake of <^3H> -glucosamine as a marker of GAG into epithelium and connective tissue in healthy gingiva of dog was determined quantitatively and qualitatively (Iwayama). Human derived fibroblasts with collagen fibers were incubated and dynamics of fibroblasts was observed with respect to tissue repair (Yajima). After condensation of hydroxyapatite granules into experimental vertical alveolar defects of monkeys, periodontal repair was observed histopathologically (Ishikawa). After condensation of bioglass particles into experimental vertical defects of beagle dogs, periodontal repair was observed histopathologically (Sueda). After condensation of <beta> -tricalcium phosphate granules into experimental vertical alveolar defects of dogs, periodontal repair was observed histopathologically (Hara). Effects of free gingival grafts on alveolar plate with and without periosteum were investigated microscopically (Ueno).
|
