| Project/Area Number |
60570449
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| Research Category |
Grant-in-Aid for General Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Research Field |
Pediatrics
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| Research Institution | Department of Pediatric Cardiology, The Heart Institute of Japan Tokyo Women's Medical College |
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Principal Investigator |
SATOMI Gengi Resident, Dept. of Pediatric Cardiology, Tokyo Women's Medical College, 医学部, 助手 (90119967)
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| Co-Investigator(Kenkyū-buntansha) |
MOMMA Kazuo Associate Professor, Dept. of Pediatric Cardiology, Tokyo Women's Medical Colleg, 心研小児科, 助教授 (80075233)
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| Project Period (FY) |
1985 – 1986
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| Project Status |
Completed (Fiscal Year 1986)
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| Budget Amount *help |
¥1,600,000 (Direct Cost: ¥1,600,000)
Fiscal Year 1986: ¥300,000 (Direct Cost: ¥300,000)
Fiscal Year 1985: ¥1,300,000 (Direct Cost: ¥1,300,000)
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| Keywords | Two-dimensional echocardiography / noninvasive diagnosis / congenital heart disease / 胎児心エコー図 |
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| Research Abstract |
Two-dimensional echocardiography is a useful method for noninvasive diagnosis of congenital heart disease. As the number of emergency operation without catheterization for new born patients with severe congenital heart disease has been increased, the detail and correct information about the malformed heart is required. We compared multiple cross-sections of the new born heart of rat, which was made using a frozen section technique, with the image of two-dimensional echocardiography in human neonates. Each portion of intra and peri-cardiac structure was identified by this method. Then we advanced to identify cross-section of fetal heart of rat by using the same technique. As a results, detailed anatomical identification has been possible in a neonatal and fetal heart. A case with complete endocardial cushion defect was correctly diagnosed by two-dimensional echocardiography in utero.
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