| Project/Area Number |
60570766
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| Research Category |
Grant-in-Aid for General Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Research Field |
Obstetrics and gynecology
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| Research Institution | Akita University |
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Principal Investigator |
HIGUCHI Motokazu Dept. Obstetrics and Gynecology, Akita University, School of medicine, 医学部, 講師 (20006779)
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| Co-Investigator(Kenkyū-buntansha) |
HIRANO Hideto Dept. Obstetrics and Gynecology akita University, School of medicine, 医学部, 助手 (80156687)
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| Project Period (FY) |
1985 – 1987
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| Project Status |
Completed (Fiscal Year 1987)
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| Budget Amount *help |
¥1,800,000 (Direct Cost: ¥1,800,000)
Fiscal Year 1987: ¥300,000 (Direct Cost: ¥300,000)
Fiscal Year 1986: ¥400,000 (Direct Cost: ¥400,000)
Fiscal Year 1985: ¥1,100,000 (Direct Cost: ¥1,100,000)
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| Keywords | Fetus / Fetal Maturation / Fetal Breathing Movements / Fetal Heart Rate / Central Nervous System / Amniotic Fluid / 羊水 / 胎児神経系成熟度 / 胎児心拍一過性頻脈 / 胎動 |
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| Research Abstract |
The possibility of the assessment of functional maturation of human fetal lung was investigated in this study through the analysis of fetal breathing movements (FBM) by real time ultrasonic B-scanner. The relationship between the frequencies of the various durations of FBM and the age of gestation was studied in 15 normal pregnant women. The frequency of successive FMB with a duration of 【ltoreg】10 sec. decreased sigificantly from 25 to 32 weeks of gestation. The frequency of succssive FBM lasted for 【gtoreg】30 sec. showd a significant increase at the same age. An intimate correlation was demonstrated between the the freqency of FBM lasted for 10 【gtoreg】30 sec., the number of fetal heart rate accelerations per hour and the value of long term valiavility. These results suggest that a prolongation of the duration of successive FBM fo the fetus is related to the functional development of the central nervus system.
The pattern of FBM classified into 3 types by the depth, irregularity and the duration of FBM in 72 pregnant women who eventually underwent preterm deliveries. The incidence of neonatal respiratory disturbances including RDS decreased sigificantly with a maturation of FBM pattern. From these results showed that the analysis of FBM could contibute to the prenatal evaluation of the functional maturity of human fetal lung.
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