| Project/Area Number |
60570787
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| Research Category |
Grant-in-Aid for General Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Research Field |
Obstetrics and gynecology
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| Research Institution | Miyazaki Medical College |
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Principal Investigator |
MIYAKAWA Isao Associate Professor, Dept. of Obstet. & Gynecol. Miyazaki Medical College, 医学部, 助教授 (70040607)
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| Co-Investigator(Kenkyū-buntansha) |
YASUDA Hiroshi Instructor, Dept. of Obstet. & Gynecol., Miyazaki Medical College, 医学部附属病院, 助手 (90174515)
TANIYAMA Keiichi Instructor, Dept. of Obstet. & Gynecol., Miyazaki Medical College, 医学部, 助手 (00145418)
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| Project Period (FY) |
1985 – 1986
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| Project Status |
Completed (Fiscal Year 1986)
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| Budget Amount *help |
¥1,600,000 (Direct Cost: ¥1,600,000)
Fiscal Year 1986: ¥300,000 (Direct Cost: ¥300,000)
Fiscal Year 1985: ¥1,300,000 (Direct Cost: ¥1,300,000)
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| Keywords | Parturition / Initiation of labor / Prolactin / Toxemia of pregnancy |
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| Research Abstract |
Recent years, many studies have brought greater understandings of the control of parturition in the laboratory animals. However, the endocrinological control mechanism on initiation of parturition in human has remained to be elucidated.
In this project, the endocrinological studies have been done on the control of parturition in human.
1.Plasma prolactin levels were measured in 21 patients with severe toxemia of pregnancy and in 111 normal pregnant women. Correlations between prolactin concentration and the severity of renal function in toxemic patients, and preterm delivery were discussed. A part of the results was reported in " Prolactin in severe toxemia of pregnancy, Eur. J. Obstet. Gynecol. Reprod. Biol., 23: 25--30, 1986." [ See reference, next page ]
2." Effects of dehydroepiandrosterone sulfate ( DHA-S ) to prolactin secretion and induction of labor in term pregnant women " was studied in 1986. Various hormones ( PRL, <E_2> -17 <beta> , <E_3> , DHA-S ) were measured in nine term pregnant women who were administered 100 mg of DHA-S intravenously, and in seven pregnant women as controls. The results will be reported in " Prolactin Conference " in Tokyo in October, 1987.
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