Experimental study on function and morphology of the excretory salivary duct in health and disease.
Project/Area Number |
60570854
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Research Category |
Grant-in-Aid for General Scientific Research (C)
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Allocation Type | Single-year Grants |
Research Field |
Morphological basic dentistry
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Research Institution | Iwate Medical University |
Principal Investigator |
TAKEDA Yasunori School of Dentistry, Iwate Medical University, 歯学部, 講師 (60137536)
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Co-Investigator(Kenkyū-buntansha) |
FUKUTA Yohko School of Dentistry, Iwate Medical University, 歯学部, 助手 (70165372)
FUJIMURA Akira School of Dentistry, Medical University, 歯学部, 助手 (80173459)
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Project Period (FY) |
1985 – 1986
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Project Status |
Completed (Fiscal Year 1986)
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Budget Amount *help |
¥1,500,000 (Direct Cost: ¥1,500,000)
Fiscal Year 1986: ¥600,000 (Direct Cost: ¥600,000)
Fiscal Year 1985: ¥900,000 (Direct Cost: ¥900,000)
|
Keywords | Excretory duct of the salivary gland / Parotid duct / Salivary secretion / Salivary duct / Sialadenosis / Sialolith / Lymphocytes / Oncocytosis / Hemochromatosis / Xerostomia / Assessory parotid gland / Calcification |
Research Abstract |
1) Microanatomical study of the human parotid duct: The parotid duct, much like other excretory passages, possessed three histological coats: mucosa, muscular layer and adventitia. The mucous epithelium was composed tall columnar cells and basal cells, and circular elastic fibers were in close vicinity to the epithelium. The muscular layer consisted of smooth muscular fibers running in logitudinal direction. The results of the present study suggest that the parotid duct contributes to control of salivary secretion, since its architecture is basically similar to that of other excretory passages which have peristaltic activity. 2) Histological and ultrastructural studies of the parotid duct of macaca irus: The parotid duct contributes to control of salivary secretion, since their histoarchitecture is basically similar to that of other ducts or canals which have peristaltic activities. Furthermore, in macaca irus it may be inferred that parotid epithelium modify primary saliva by adding a
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mucous protein to it, since numerous mucous secreting goblet cells are observed in innermost layer of the epithelium in spite of no inflammatory changes in and around the duct epithelium. In addition to the above-mentiond studies, following studies were made: 3) Cryatalloids with calcareous deposition in the parotid gland: one of the possible causes of the development of salivary calculi. 4) Enlargement of rat submandibular salivary gland induced by single amputation of lower incisor teeth: histological, histometric and ultrastructural study. 5) Focal lymphocytic infiltration in the human labial salivary glands: a postmortem study. 6) Interepithelial lymphocytes of the rat submandibular gland. 7) Diffuse hyperplastic oncocytosis of the parotid gland. 8) Sicca symptom in patient with hemochromatosis: minor salivary gland biopsy for differential diagnosis, and study on a postmortem series. 9) Histological study on human accessory parotid gland. 10) Calcified substance in and around the duct system of the human submandibular gland. 11) Intra-nodal salivary gland epithelia in lymph nodes of human head and neck regions. Less
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Report
(1 results)
Research Products
(11 results)