| Project/Area Number |
61440060
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| Research Category |
Grant-in-Aid for General Scientific Research (A)
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| Allocation Type | Single-year Grants |
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| Research Field |
Digestive surgery
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| Research Institution | KYOTO UNIVERSITY |
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Principal Investigator |
TOBE Takayoshi 1st Department of Surgery, Faculty of Medicine, Kyoto University. Professor, 医学部, 教授 (70025641)
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| Co-Investigator(Kenkyū-buntansha) |
INOUE Kazutomo 1st Department of Surgery, Faculty of Medicine, Kyoto University. Instructor, 医学部, 講師 (90168435)
YAJIMA Haruaki Niigata Pharmacy College. Chancellor, 学長 (00025678)
HAMASHIMA Yoshihiro Kyoto Women College. Chancellor, 学長 (00089103)
安達 秀樹 京都大学, 医学部, 講師 (80093178)
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| Project Period (FY) |
1986 – 1989
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| Project Status |
Completed (Fiscal Year 1989)
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| Budget Amount *help |
¥17,300,000 (Direct Cost: ¥17,300,000)
Fiscal Year 1989: ¥2,100,000 (Direct Cost: ¥2,100,000)
Fiscal Year 1988: ¥2,000,000 (Direct Cost: ¥2,000,000)
Fiscal Year 1987: ¥6,000,000 (Direct Cost: ¥6,000,000)
Fiscal Year 1986: ¥7,200,000 (Direct Cost: ¥7,200,000)
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| Keywords | chronic dog with pancreatic and gastric fistulas / chronic dog with biliary, pancreatic and gastric fistulas / splanchnic circulation / gastrointestinal hormones / synthetic human CCK-33 / pancreatoduodenectomy / gallbladder dysfunction after gastrectomy / segmental autotransplantation of the pancreas / 腹部臓器血行動態 / 意識下血行動態 / 合成ヒトCCKー33 / レセプタ- / 移植膵血行動態 / ラ氏島の電顕観察 / 膵分泌 / 胆汁分泌 / CCK / 超音波トランジットタイム血流計 / レーザードップラー血流計 / 意識下血流 / 膵移植 / 意識下膵外分泌 / 意識下胆汁分泌 / 肝胆膵胃腸臓器相関 / 術中臓器血流測定 / 意識下臓器血行動態 / 意識下膵外分泌動態 / 臓器血行動態 / 胃切除 / 胆嚢運動機能 |
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| Research Abstract |
Summary of research results of this project is as follows. 1) Clarification of the relationship between biliary and pancreatic secretions and the released of gastrointestinal hormones in the conscious state. 2) Clarification of the physiological changes of splanchnic circulation by simultaneous use of laser Doppler flowmetry and ultrasonic transit-time flowmeter. 3) Clarification of the physiological significance of larger molecular forms of CCK 4) Evaluation of Billroth I type of reconstruction as a physiological and pertinent reconstruction procedure after pancreatoduodenectomy in relation to the release of gastrointestinal hormones 5) Clarification of the mechanism of gaubladder dysfunction gastrectomy with special reference to changes of release of gastrointestinal hormones 6) Observation on the relatively well preservation of the hemodynamics of the segmental autotransplanted pancreas.
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