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Developement of the non-invasive deep-body temperature measuring method by reflected Ultrasouna

Research Project

Project/Area Number 61460149
Research Category

Grant-in-Aid for General Scientific Research (B)

Allocation TypeSingle-year Grants
Research Field 計測・制御工学
Research InstitutionInst. of Med. electronics,Faculty of Medicine,University of Tokyo.

Principal Investigator

SAITO Masao  Inst.ofMed.electronics,Faculty of Medicine,University of Tokyo, 医学部, 教授 (60010708)

Co-Investigator(Kenkyū-buntansha) TKEDA Kenji  Inst.ofMed.electronics,Faculty of Medicine,University of Tokyo, 医学部, 助手 (70010030)
WATANABE Akira  Inst.ofMed.electronics,Faculty of Medicine,University of Tokyo, 医学部, 助教授 (00009937)
Project Period (FY) 1986 – 1987
Project Status Completed (Fiscal Year 1987)
Budget Amount *help
¥5,800,000 (Direct Cost: ¥5,800,000)
Fiscal Year 1987: ¥1,700,000 (Direct Cost: ¥1,700,000)
Fiscal Year 1986: ¥4,100,000 (Direct Cost: ¥4,100,000)
KeywordsUltrasound / Non-invasive temperature mcasurement / 生体温度計測 / 減衰定数
Research Abstract

Present uses of thermocouple and thermistor in measuring body temperature face many problems. For example, the problem of limited number of measured points and metastasis in hyperthermia thermometry. These problems necessitate non-invasive temperature measurement. When ultrasound propagated through biological material, its physical parameters such as attenuation and velocity vary with temperafure. Among these parameters, attenuation seems the most practical since the existing B-mode device can be used to analyze the attenuation of reflected ultrasonic signal. The purpose of this study is to show the possibility of non-invasive temperature measurement method based on the above principle.
In biological tissuse, structural relaxation processes, with an appropriate distribution of relaxation times and the contribution due to viscosity, give rise to the measured attenuation coefficient. Because viscosity and relaxation processes are related to the temperature through viscosity coefficient and relaxation times at different temperature, respectively, the attenuation coefficient is a function of temperature. Consequently, the temperature will be measured indirectly by estimating attenuation coefficient parameter.
For basic study, the in vitro experiments using pig livers, pig fillets, beef livers and beef muscles were investigated. The technique used to analyze the temperature dependence of attenuation cofficient is the spectral-difference method. The experimental results indicate that the temperature dependences of attenuation coefficients of liver and muscle in the temperature range of 37-46゜C are in the order of -.006 to -.011 dB/(cm.MHz.K). In vivo experiment using pig liver also shows the negative dependency. By a more accurate instrumentation and signal processing, with preliminary known characteristics of the temperature dependences of attenuation coefficients of the tissuse of interest, it is possible to measure the tissue temperature non-invasively by this method.

Report

(2 results)
  • 1987 Final Research Report Summary
  • 1986 Annual Research Report
  • Research Products

    (8 results)

All Other

All Publications (8 results)

  • [Publications] 椎名毅: 電子情報通信学会論文誌. J69-A. 19085-1093 (1986)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] W. Benjapolakul: 日本超音波医学会第48回講演論文集. 665-666 (1986)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] 斎藤正男: 癌と化学療法. Vol.13. (1986)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] 田坂晧他編, 斎藤正男: "「放射線医学体系」温度測定技術" 中山書店, 285 (1987)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] W.Benjapolakul: "Basic Discussion on Non-Invasive Temperature Measurement by Reflected Ultrasound" Proc. 48th Conf.Jap.J.Medical Ultrasorics. 665-666 (1986)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1987 Final Research Report Summary
  • [Publications] 椎名毅: 電子通信学会論文誌. J69-A. 1085-1093 (1986)

    • Related Report
      1986 Annual Research Report
  • [Publications] 斎藤正男: 癌と化学療法. vol13,No.4. (1986)

    • Related Report
      1986 Annual Research Report
  • [Publications] 椎名毅,鈴木良次,池田研二他編: "「生体信号の計測と相関・スペクトル解析」" コロナ社, (1987)

    • Related Report
      1986 Annual Research Report

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Published: 1987-03-31   Modified: 2016-04-21  

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