| Project/Area Number |
61480126
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| Research Category |
Grant-in-Aid for General Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Pathological medical chemistry
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| Research Institution | Shinshu University |
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Principal Investigator |
TAKETOMI Tamotsu Institute of Cardiovascular Disease, Shinshu University School of Medicine, 医学部附属心脈管研究施設, 教授 (30020704)
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| Co-Investigator(Kenkyū-buntansha) |
HARA Atsushi Institute of Cardiovascular Disease, Shinshu University School of Medicine, 医学部附属心脈管研究施設, 講師 (70126697)
UEMURA Kei-ichi Institute of Cardiovascular Disease, Shinshu University School of Medicine, 医学部附属心脈管研究施設, 助教授 (80012756)
岡野 照 信州大学, 医学部附属心脈管病研究施設, 助手 (30020803)
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| Project Period (FY) |
1986 – 1988
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| Project Status |
Completed (Fiscal Year 1988)
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| Budget Amount *help |
¥5,000,000 (Direct Cost: ¥5,000,000)
Fiscal Year 1988: ¥500,000 (Direct Cost: ¥500,000)
Fiscal Year 1987: ¥1,000,000 (Direct Cost: ¥1,000,000)
Fiscal Year 1986: ¥3,500,000 (Direct Cost: ¥3,500,000)
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| Keywords | Anti-atherosclerotic effect / Atherosclerosis / Foam cells / LDL / Lysophosphatidylcholine / Macrophage / Smooth muscle cell / Sulfatide / スルファチド / コレステロール / コレステロール・エステル / LysoPC / WHHL-rabbit / コレステロール結晶沈着 / スフィンゴミエリン / エタノールアミン・プラスマロゲン / WHHLウサギ / 動脈硬化 / スティンゴ糖脂貭 / 脂肪酸 / 長鎖塩基 / 動脈硬化性病変 / 酸性糖脂質 |
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| Research Abstract |
These results suggest an important role of 5 hemopoietic factors (IL-3, IL-4, IL-6. IL-1, G-CSF) on the development of multipotential hemopoietic progenitors in vitro and the clinical application of these factors to bone marrow transplantation and hematological disorders such as aplastic anemia.
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