| Project/Area Number |
61480233
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| Research Category |
Grant-in-Aid for General Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Radiation science
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| Research Institution | University of Tsukuba |
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Principal Investigator |
KITAGAWA Toshio University of Tsukuba, Professor, 臨床医学系, 教授 (80076942)
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| Co-Investigator(Kenkyū-buntansha) |
NISHIDA Masato University of Tsukuba, Lecturer, 臨床医学系, 講師 (00110875)
OTANI Mikinobu University of Tsukuba, Lecturer, 臨床医学系, 講師 (80133081)
YOSHII Yoshihiko University of Tsukuba, Lecturer, 臨床医学系, 講師 (50110507)
ARIMOTO Takuro University of Tsukuba, Lecturer, 臨床医学系, 講師 (50168027)
TAKASE Yasuhiro University of Tsukuba, Lecturer, 臨床医学系, 講師 (50075339)
石川 悟 筑波大学, 臨床医学系, 講師 (70168194)
金子 実 筑波大学, 臨床医学系, 助教授 (00111378)
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| Project Period (FY) |
1986 – 1988
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| Project Status |
Completed (Fiscal Year 1988)
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| Budget Amount *help |
¥7,500,000 (Direct Cost: ¥7,500,000)
Fiscal Year 1988: ¥2,500,000 (Direct Cost: ¥2,500,000)
Fiscal Year 1987: ¥2,000,000 (Direct Cost: ¥2,000,000)
Fiscal Year 1986: ¥3,000,000 (Direct Cost: ¥3,000,000)
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| Keywords | Proton therapy / 標識埋没法 / 放射線治療 / 放射線照射技術 / 照射技術 |
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| Research Abstract |
Interstitial implantation tchnoque of markers to confirm a silhouette of of tumor in deep-seated organs in procedures of treatment planning and irradiation field set up was investigated in this study. Tiny metal seeds were implanted in normal tissue at border of tumor lesion using newly designed instruments for endoscopic or palpative approaches. The marker implanted in tissue appeared as a fine small spot in X ray films or in CT films. Outline of the tumor lesion was obtained according to the silhouette of those markers. Using the outline, confirmation of treatment planning on CT films and irradiation field on X ray films was able to performed precisely. According to improvement of accuracy in those procedures, proton beam were able to irradiate tumor lesion selectively and successfully including impossible lesions to figure their out lines with conventional techniques. This technique is to be contributed to development of the indication range in proton therapy.
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