| Project/Area Number |
61480323
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| Research Category |
Grant-in-Aid for General Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Orthopaedic surgery
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| Research Institution | Tokai university school of medicine |
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Principal Investigator |
IMAI Nozomu Tokai univ. school of medicine, 医学部, 教授 (30055743)
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| Co-Investigator(Kenkyū-buntansha) |
TERADA Hiroshi Tokai univ. school of medicine, 医学部, 助手 (50188679)
NOGUCHI Takatoshi Tokai univ. school of medicine, 医学部, 助手 (30164677)
TOMATSU Taisuke Toaki univ. school of medicine, 医学部, 助教授 (40112693)
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| Project Period (FY) |
1986 – 1987
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| Project Status |
Completed (Fiscal Year 1987)
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| Budget Amount *help |
¥6,300,000 (Direct Cost: ¥6,300,000)
Fiscal Year 1987: ¥1,500,000 (Direct Cost: ¥1,500,000)
Fiscal Year 1986: ¥4,800,000 (Direct Cost: ¥4,800,000)
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| Keywords | bone-cartilage lesion / internal derangement of the knee / patello-femoral malalignment / bone-cartilage graft / 骨軟骨移植 / 離断性骨軟骨炎 / 関節軟骨 / 骨軟骨々折 / 軟骨軟化症 / 膝蓋大腿関節適合不良 / バイオメカニックス / X線学的研究 |
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| Research Abstract |
In this series, We carried out the experimentalnd clinical study of bone-cartilage lesions in the derangement of the knee. In thebiomechanical experiment, the articular enda of the femoral condyle of the pig knees were used. The shearing force under the various loading conditions was givenon the articular surface at the angle of 120 15 degerees. The experimental lesions of the bone-cartilage composite was classified into 8 types and we found that there were two types of processes of bone-cartilage lesions by shearing force. One was the high speed lesion, that was outside lesion of cartilage without the inside damage. The other was the low speed lesion without out side damage. And both process evebtually produced both cartilage and bone destruction. The pathogenesis of the clinical cartilage-bone lesions was well explained by the experimental data. Open splitting at cartilage-bone junction and open subchondral fracture were identical to the osteochondral fracture, that was seen in the patellar dislocation. The closed splitting of uncalcified cartilage was possible to be the precursive lesion of chondromallacia. Some of the closed subchondral lesions may develope theosteochondritis dissecans.
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