| Project/Area Number |
61480486
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| Research Category |
Grant-in-Aid for General Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Pediatrics
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| Research Institution | Nihon University |
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Principal Investigator |
MUGISHIMA Hideo Nihon University School of Medicine Assistant Professor, 医学部, 講師 (80183648)
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| Co-Investigator(Kenkyū-buntansha) |
市川 正孝 日本大学, 医学部, 助手
陳 茎明 日本大学, 医学部, 助手
SUZUKI Takashi Nihon University School of Medicine Fellow, 医学部, 助手
TAKAHASHI Hideo Nihon University School of Medicine Fellow, 医学部, 助手
CHIN Motoaki Nihon University School of Medicine Fellow (50277422)
ICHIKAWA Masataka Nihon University School of Medicine Fellow
陳 基明 日本大学, 医学部, 助手
藤沢 孝人 日本大学, 医学部, 助手
川田 孝吉 日本大学, 医学部, 助手
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| Project Period (FY) |
1986 – 1988
|
| Project Status |
Completed (Fiscal Year 1988)
|
| Budget Amount *help |
¥2,400,000 (Direct Cost: ¥2,400,000)
Fiscal Year 1988: ¥800,000 (Direct Cost: ¥800,000)
Fiscal Year 1987: ¥800,000 (Direct Cost: ¥800,000)
Fiscal Year 1986: ¥800,000 (Direct Cost: ¥800,000)
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| Keywords | Neuroblastoma / Autologous bone marrow transplantation / Magnetic immunobeads mathod / Tumor cell purging / N-myc遺伝子 / MagneticーImmunobeads法 / Maghetic Immunobeads |
|---|
| Research Abstract |
We have successfully reconstituted G patients with stage N^^- nauroblastoma whose marron was treated in vitro by monoclonal antibodies/magnetic immunobeads, the intensive chemoradio thevary and purged autologous marrow transplant, if carried out before development of progressive disease, will improve the outcome of patients with poor prognosis neuroblastoma.
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