Efferent projections of the cingulate gyrus and an attempt of their multiple labelings.

Research Project

Project/Area Number	61570025
Research Category	Grant-in-Aid for General Scientific Research (C)
Allocation Type	Single-year Grants
Research Field	神経解剖学
Research Institution	Hamamatsu University, School of Medicine
Principal Investigator	FUJII Masako Associate Professor, Hamamatsu University School of Medicine, 医学部, 助教授 (00010033)
Project Period (FY)	1986 – 1987
Project Status	Completed (Fiscal Year 1987)
Budget Amount *help	¥1,900,000 (Direct Cost: ¥1,900,000) Fiscal Year 1987: ¥500,000 (Direct Cost: ¥500,000) Fiscal Year 1986: ¥1,400,000 (Direct Cost: ¥1,400,000)
Keywords	cat / monkey / WGA-HRP method / WGA / choleragenoid / ABC method / ABC-AP method / cingulate gyrus / ABC-AP法 / ニホンザル
Research Abstract	Cortico-cortical projections of the cingulate gyrus in the cat and monkey were examined by the WGA-HRP method. In general, the cortico-cortical connections of the cingulate gyrus are reciprocal. In this abstract the reciprocal connections are said only the cortico-cortical conncetions. In the cat and monkey characteristics of the cortico-cortical connections are as follows: 1) The main cortico-cortical connections are with frontal, parietal and temporal association cortices, and paralimbic cortices, and 2) The findings in 1) are mostly common throughout the supra-callosal cingulate gyrus except the most anterior part which fail to connect with the parietal association cortex. In the cat following three cortico-cortical projections, homologous projections of which are demonstrated also in the monkey, are selected for the double-labeling method. 1) The anterior and middle parts of the suprasylvian gyrus (Area 7), 2) Areas around and periphery of the proreus gyrus (frontal association cortex and paralimbic cortex), 3) Areas in and around the rhinal sulcus (paralimbic cortex). In these three areas WGA or choleragenoid was injected and the axonal transports were immuno-histochemically investigated with ABC or ABC-AP method. Double labelings of the retrograde transport of the WGA or choleragenoid could not be noticed in any of a pair of these series. Frim these results the cortico-cortical projections of the cingulate neurons to the association and paralimbic cortices appear to be point to point projections, not extensive collateral innervations.