| Project/Area Number |
61570758
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| Research Category |
Grant-in-Aid for General Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Research Field |
Urology
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| Research Institution | Niigata University |
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Principal Investigator |
KANO Ken-ichi Associate Professor, Niigata University School of Medicine, 医学部, 助教授 (50018686)
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| Co-Investigator(Kenkyū-buntansha) |
HANYU Shugo Assistant, Niigata University Medicine Hospital, 医学部附属病院, 助手 (80172956)
IWANAGA Toshihiko Assistant, Niigata University School of Medicine, 医学部, 助手 (10160128)
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| Project Period (FY) |
1986 – 1987
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| Project Status |
Completed (Fiscal Year 1987)
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| Budget Amount *help |
¥2,000,000 (Direct Cost: ¥2,000,000)
Fiscal Year 1987: ¥1,000,000 (Direct Cost: ¥1,000,000)
Fiscal Year 1986: ¥1,000,000 (Direct Cost: ¥1,000,000)
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| Keywords | Mechanism of penile erection / Vascular construction of penis / Intracavernous pressure / Blood flow in cavernous sinuses / Dog / Monkey / イヌ / イヌ陰茎 / 勃起のメカニスム / 血管鋳型 / 神経 |
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| Research Abstract |
The vascular constructions of the dog, monkey and human were investigated mainly by scanning electron microscopic observation of corrosion casts produced by injection of methylmethacrylate into the penile arteries and there branches. The corpus cavernosum penis were supplied mainly by the penile deep arteries. The helicine arteries of the dog and monkey were provided with polsters which protruded into the lumen, but no polster occurred in human. The polster might conspicuously reduce the luminal space during the flaccid state of the penis. the postcavernos venules in the corpus cavernosum penis occurred only on their dorsal surface. The postcavernous venules ran for a distance beneath the tunica albuginea, and it is apparent that they are effectively compressed between the tunica albuginea and the peripheral sinuses during erection. The penetrating veins with large calibers were also constricted in the region which corresponded to the inner half of the tunica albuginea during erection. No arterio-venous anastomoses could be found either within or out of the cavernous bodies in the dog and monkey. In the man, existence of the anastomosis has been under investigation.
In the pressure study, it was made clear that the cavernous presssure in the dog was elevated as high as five times the perfusion pressure as a result of the arterial and venous occlusion isolated the cavernous sinus from systemic circulation in the rigid state.
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