| Project/Area Number |
61570906
|
|---|
| Research Category |
Grant-in-Aid for General Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Conservative dentistry
|
|---|
| Research Institution | Hokkaido Univ. |
|---|
Principal Investigator |
SHIMOKOBE Hirokata School of Dentistry , Hokkaido Univ., 歯学部, 教授 (20014011)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
TANAKA Toru Dental Hospital, Hokkaido Univ., 歯学部附属病院, 助手 (90179771)
MATSUI Ichiro Dental Hospital, Hokkaido Univ., 歯学部附属病院, 助手 (50133757)
SAWANO Keiji School of Dentistry, Hokkaido Univ., 歯学部, 助手 (10109465)
中村 裕信 北海道大学, 歯学部, 助手 (50172432)
|
|---|
| Project Period (FY) |
1986 – 1987
|
| Project Status |
Completed (Fiscal Year 1987)
|
| Budget Amount *help |
¥1,900,000 (Direct Cost: ¥1,900,000)
Fiscal Year 1987: ¥500,000 (Direct Cost: ¥500,000)
Fiscal Year 1986: ¥1,400,000 (Direct Cost: ¥1,400,000)
|
|---|
| Keywords | Diode Laser / Dentin Hypersensitivity / 歯髄変化 / レーザー / 知覚過敏 / 象牙質 / 半導体 |
|---|
| Research Abstract |
Recent studies have shown the effects of diode laser irradiation in treatment for dentin hypersensitivities. However,the system of the effects still remains unsolved. The conditions and indications of irradiation in the diseases are, therefore, not defined in detail, which decreases clinical reliability of the laser therapy for pain.
The study was designed to examine histopathological change of dental pulp tissue by laser irradiation to know the mechanism of the effects.
Continuous irradiation at 30mW was performed for 60 and 90 seconds under direct contact of a probe to occlusal surface of the first molars of male Wistar rats by using Ga-Al-As diode laser(<lambda>: 830nm, Osada Electric Co.). The rats were sacrificed 2 weeks after irradiation and the pulp tissues were routinely examined histopathologically under light microscope. Clinical examination also done on the patients having hypersensitive dentinunder their consents.
Experiments indicate ; 1) No differences were detected in histopathological appearance of pulp tissues between irradiated and non-irradiated groups in this study. Since loss of pain by laser irradiation may give some histological change to pulp tissue, ultratine structure investigation would find the changes in future. 2) In clinical experiment, of 61 cases, the findings showing remarkable effective, effective, and non-effective were 10(16%), 29(48%), and 22(36%) cases, respectively. Though the laser irradiation yielded immediate effect, pain returned in some cases. This uncertain clinical results suggested further study on informations of dentin hypersensitivity to get higher clinical reliability.
|
