Development of Directly Coupled Supercritical Fluid Chromatograph-Mass Spectrometer System
| Project/Area Number |
61850139
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| Research Category |
Grant-in-Aid for Developmental Scientific Research
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| Allocation Type | Single-year Grants |
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| Research Field |
工業分析化学
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| Research Institution | Nagoya University |
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Principal Investigator |
TSUGE Shin Professor of Nagoya University, 工学部, 教授 (60023157)
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| Co-Investigator(Kenkyū-buntansha) |
HIRATA Yukio Associate Professor, 助教授 (10126948)
MATSUMOTO Kozo Research Assistant of Nagoya University, 工学部, 教務職員 (80109305)
OHTANI Hajime Research Associate of Nagoya University, 工学部, 助手 (50176921)
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| Project Period (FY) |
1986 – 1988
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| Project Status |
Completed (Fiscal Year 1988)
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| Budget Amount *help |
¥16,100,000 (Direct Cost: ¥16,100,000)
Fiscal Year 1988: ¥600,000 (Direct Cost: ¥600,000)
Fiscal Year 1987: ¥1,700,000 (Direct Cost: ¥1,700,000)
Fiscal Year 1986: ¥13,800,000 (Direct Cost: ¥13,800,000)
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| Keywords | Supercritical fluid chromatography / Supercritical fluid chromatography-mass spectromtry System / Vitamin analysis / Oligomeric polymer analysis / Non-ionic surface agents / トリグリセリド分析 / 超臨界流体クロマトグラフィーー質量分析法直結システム / ポリエチレングリコール / エポキシプレポリマー / オリゴマー / 超臨界液体クロマトグラフィー |
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| Research Abstract |
Supercritical fluid chromatography(SFC) has been vigorously investigated and recognized as a rapid and powerful technique for separating non-volatile and thermally unstable compounds. Sine most of the mobile phases for SFC such as carbon dioxide and pentane have much higher volatility than those for ordinary HPLC, SEC is principally much feasible to make a direct coupling system with a mass spectrometr(SFC-MS). in this project, the SFC with the fused silica packed capillary column was directly coupled with a quadrupole MS through a vacuum nebulizing interface originally developed for HPLC-MS. Thus developed SFC-MS system was successfully applied to various non-volatile samples such as polystyrene oligomers, non-ionic surface agentswwhich are composed of complexed mixture of of origomeric polymers, phthalates, triglycerides, polyethylene glycol(PEG)derivatives and vitamins.
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Report
(3 results)
Research Products
(23 results)
