| Project/Area Number |
61890001
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| Research Category |
Grant-in-Aid for Developmental Scientific Research
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| Allocation Type | Single-year Grants |
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| Research Field |
広領域
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| Research Institution | Hirosaki University |
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Principal Investigator |
INO-U-E Shigeaki Hirosaki University Hospital Assistant, 医学部附属病院, 助手 (00168444)
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| Co-Investigator(Kenkyū-buntansha) |
志田 正一 弘前大学, 医学部附属病院, 医員
ENDOH Masaaki Hirosaki University School of Medicine Assistant, 医学部, 助手 (30194046)
SHIDA Shoichi Hirosaki University Hospital Assistant
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| Project Period (FY) |
1986 – 1988
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| Project Status |
Completed (Fiscal Year 1988)
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| Budget Amount *help |
¥4,000,000 (Direct Cost: ¥4,000,000)
Fiscal Year 1988: ¥700,000 (Direct Cost: ¥700,000)
Fiscal Year 1987: ¥1,000,000 (Direct Cost: ¥1,000,000)
Fiscal Year 1986: ¥2,300,000 (Direct Cost: ¥2,300,000)
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| Keywords | Cholangioscopic microwave lithotomy / Microwave coaxial cable / Microwave antenna / Irrigation materials / Cholelitholytic agents / Methyl tert-Butyl Ether (MTBE) / Fluorocarbon / 衝撃波 / 非観血的胆石治療 / 肝内・総胆管結石 / マイクロ波砕石 / 胆道鏡 / 同軸ケーブル / アンテナ / 内視鏡 / マイクロ波 / レーザー / 超音波 / 肝内結石 / 総胆管結石 |
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| Research Abstract |
Microwave coaxial cable; Thelenyth and diameter which are the limiting factors for resistance and capacitance of the cable were shown as 90cm and 1.80mm, respectively in a flexible slender cholangioscopic channel (FCN-15H).2. Output and shapes of microwave antennas for lithotomy; As to the output level, antennas were placed in such order as doublet, dipolar, spherical, monopolar, and tapering mono-polar shapes. Otherwise, taking such factors into consideration as resistance against insertion into a stone, injury of the cholangioscopic channel and an angulation of the apical portion of the scope, a short bipolar or monopolar antenna was preferable to other types. For a hard stone, utilization of a spherical antenna following bipolar or monopolar one was recommended. 3. Irrigation materials; feasibility of an antenna insertion into a hard stone increased in 5% glucose because of decreased current dissipation. 4. Utilization of cholelitholytic agents; Methyl tert-Butyl Ether (MTBE) softened the hard surface of a stone followed by an easy insertion of an antenna, and developed the indication of microwave lithotomy for hard cholesterol stones. Fluorocarbon was shown to be an excellent mixture solvent and a volume expander of MTBE to prevent its adverse effeots. 5. Microweve lithotony gave a hold in a hard stone (borehole) for other lithotriptors (shock wave method etc).
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