| Project/Area Number |
62041810
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| Research Category |
Grant-in-Aid for Overseas Scientific Research
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| Allocation Type | Single-year Grants |
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| Section | Special Cancer Research |
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| Research Institution | Department of Pathology, Nihon University School of Medicine |
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Principal Investigator |
SHIKATA Toshio Nohon University, Professor, 医学部・病理, 教授 (50009932)
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| Co-Investigator(Kenkyū-buntansha) |
LALA Mo Vaiola Hospital
SIONE Sengili Vaiola Hospital
ESUMI Mariko Nihon University, Lecturer, 医学部・病理, 講師 (60160363)
UCHIDA Toshikazu Nihon University, Associate Professor, 医学部・病理, 助教授 (80060078)
INABA Yutaka Juntendo University, Associate Professor, 医学部・衛生学, 助教授 (30010094)
IINO Shiro University of Tokyo, Assistant, 医学部・内科, 助手 (30010309)
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| Project Period (FY) |
1987
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| Project Status |
Completed (Fiscal Year 1987)
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| Budget Amount *help |
¥6,900,000 (Direct Cost: ¥6,900,000)
Fiscal Year 1987: ¥6,900,000 (Direct Cost: ¥6,900,000)
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| Keywords | Hepatocellular car cinoma / Hepatitis B virus |
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| Research Abstract |
It has been postulated that hepatitis B virus (HBV) has an intimate relationship with hepatocellular carcinoma (HCC). It is supposed that some co-factors, such as afratoxin or malnutrition might promote hapatocarcinogenesis due to HBV. Question is that whether good nutrtional condition might prevent hepatocarcinogenesis due to HBV or not. We inverstigated the incidence to HCC in Tonga. Because in Tonga, carrier rate of HBV is very high and nutritional condition is rather good. Results are followes; carrier rate of HBV is high as 15%, however incidence of HCC is relatively low. There for, good mutritional condition might prevent hepatocarconogensis due to HBV.
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