| Project/Area Number |
62043060
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| Research Category |
Grant-in-Aid for Overseas Scientific Research
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| Allocation Type | Single-year Grants |
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| Section | 調査総括 |
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| Research Institution | Nagasaki University |
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Principal Investigator |
IGARASHI Akira Institute of Tropical Medicine,Nagasaki University, 熱帯医学研究所, 教授 (40029773)
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| Co-Investigator(Kenkyū-buntansha) |
ANUSORN Sidh タイ国チェンマイ県, 衛生局, 局長
PIEN Chiwani タイ国チェンマイ大学, 医学部, 教授
MORI Akio Nagasaki University,School of Medicine, 医学部, 講師 (30039557)
GOTO Hitoshi Obihiro University,Slchool of Veterinary Medicine, 畜産学部, 教授 (20003072)
FUKUNAGA Toshihiko Ryukyu University,School of Medicine, 医学部, 教授 (10029796)
CHIOWANICH Pien Chiang Mai University,Faculty of Medicine,Chiang Mai,Thailand
SIDHIRAS Anusorn Provincial Health Office,Chiang Mai Province,Chiang Mai,Thailand
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| Project Period (FY) |
1986 – 1987
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| Project Status |
Completed (Fiscal Year 1987)
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| Budget Amount *help |
¥1,500,000 (Direct Cost: ¥1,500,000)
Fiscal Year 1987: ¥1,500,000 (Direct Cost: ¥1,500,000)
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| Keywords | Antibody prevalence / Japanese encephalitis virus / dengue virus / vactor mosquitoes / タイ国北部 |
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| Research Abstract |
1.Neutralization test on blood specimens collected from healthy people at 5 sampling places showed age-depend- ent increase of antibodies against Japanese encephalitis(JE) and 4 types of dengue (DEN) viruses,however the rates were significantly lower at highlands (A,C) than those at the nearest lowlands (B,D),Maekong Valley lowland (E),and Chiang Mai Valley lowland (F),especially for DEN viruses,IgG-ELESA on measles,rubella and type 1 herpes simplex viruses did not show significant difference between the highlands and lowlands,although the antibody prevalence was not uniform among samplirg places.
2.Very few vector mosquitoes of JE and DEN viruses were found at highlands compared with abundant mosquitoes at lowlands,and similar number of DEN vector mosquito eggs were found at E and F.
3.Some of the swine at highlands showed both IgG-and IgM-ELISA antibodies against JE virus.
4.IgM-ELISA on encephalitis patients detected 32% JE cases,in contrast to 12% and 8% for meningitis and dengue haemorrhagic fever cases.
5.No apparent JE cases were fourd among 3,500 vaccinees in contrast to 1 JE case among 3,700 unvaccinated.
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