Population genetiic studies of Chinese populations: Distribution of genetic markers of human immunoglobulin G
| Project/Area Number |
62043076
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| Research Category |
Grant-in-Aid for Overseas Scientific Research
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| Allocation Type | Single-year Grants |
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| Section | 調査総括 |
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| Research Institution | Department of Legal Medicine,Osaka Medical College |
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Principal Investigator |
MATUSUMOTO Hideo Department of Legal Medicine,Osaka Medical College,Professor of Legal Medicine, 医学部, 教授 (30084809)
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| Co-Investigator(Kenkyū-buntansha) |
趙 桐茂 上海血液センター, 副所長
MIYAZAKI Tokiko Department of Legal Medicine,Osaka Medical College,Assistant, 医学部, 助手 (60084919)
SUZUKI Koichi Department of Legal Medicine,Osaka Medical College,Ledturer, 医学部, 講師 (60171211)
ZHAO Tong Mao Department of Legal Medicine,Osaka Medical College,Vice-Director of Shanghai Bol
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| Project Period (FY) |
1987
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| Project Status |
Completed (Fiscal Year 1987)
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| Budget Amount *help |
¥1,800,000 (Direct Cost: ¥1,800,000)
Fiscal Year 1987: ¥1,800,000 (Direct Cost: ¥1,800,000)
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| Keywords | Immunoglobulin allotypes / Chinese population genetics |
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| Research Abstract |
Since the discovery of Gm ab3st gene which characterizes Mongoloid populations in 1966,the distri bution of the genetic markers of human immunoglobulins (Gm) among the Mongoloid populations scattered from Southeast Asia through East Asia to South America has been investigated and concluded as follows:
1)Mongoloid populations characterized by the four Gm haplotypes,ag,axg,ab3st and afb1b3 are divided into two groups on the basis of analysis of genetic distances based on the Gm haplotype frequencies: one is a southern group characterized by a high frequency of Gm afb1b3 and a low frequency of Gm ag and the other is a northern group characterized by a hibh frequencies of Gm ag and Gm ab3st and an ex tremely low frequency of Gm afblb3.
2)Populations in China,mainly Han nationality Han nationality including minority nationalities,show remarkable hetero geneities from north to south,in sharp contrast to korean and Japanese populations showing homogeneities,respectively.The center of dispersion of the Gm afb1b3 characterizing southern Mongoloids must exist in Guangxi and Yunnan area in southwest China.
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Report
(1 results)
Research Products
(8 results)
