• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Development of Angioplasty Ring Using Thermal Shape Memory Alloy

Research Project

Project/Area Number 62440054
Research Category

Grant-in-Aid for General Scientific Research (A)

Allocation TypeSingle-year Grants
Research Field Thoracic surgery
Research InstitutionJikei University School of Medicine

Principal Investigator

SUGITA Yoichi  The Jikei Medical College Dept. of Cardiac Surgery, 心臓外科, 講師 (40130174)

Co-Investigator(Kenkyū-buntansha) SASAKI Tatsuumi  The Jikei Medical College Dept. of Cardiac Surgery, 心臓外科, 講師 (20138754)
SUZUKI Sigeru  The Jikei Medical College Dept. of Cardiac Surgery, 心臓外科, 講師 (50130175)
HORIKOSHI Sigeki  The Jikei Medical College Dept. of Cardiac Surgery, 心臓外科, 助教授 (90056987)
ARAI Tatuta  The Jikei Medical College Dept. of Cardiac Surgery, 心臓外科, 教授 (60056471)
KOZUKUE Toshiaki  The Jikei Medical College Dept. of Cardiac Surgery (10130163)
Project Period (FY) 1987 – 1989
Project Status Completed (Fiscal Year 1989)
Budget Amount *help
¥16,500,000 (Direct Cost: ¥16,500,000)
Fiscal Year 1989: ¥1,000,000 (Direct Cost: ¥1,000,000)
Fiscal Year 1988: ¥2,000,000 (Direct Cost: ¥2,000,000)
Fiscal Year 1987: ¥13,500,000 (Direct Cost: ¥13,500,000)
KeywordsAngioplasty Ring / Catheter / Thermal Shape / Memory Alloy / Angioplasty / Angioplasty Ring Stent / neointima / neointima血管内視鏡 / 偽内膜
Research Abstract

A new technique was developed for non-surgical implantation of an Angioplasty Ring to prevent restenosis following angioplasty. An Angioplasty Ring was made by thermal shape memory alloy. This thermal shape memory alloy composed of 55% nickel and 45% titanium by weight with unique thermal shape memory properties. If this alloy is constrained to a desired shape and annealed at temperatures in excess of approximately 650゚C, it will memorize that shape. However, when cooled in ice water, the wire become limp and can be deformed without destroying its memory. When this deformed wire is heated to its transition temperature, it rapidly returns to its original annealed shape.
An Angioplasty Ring Catheter used was 7F and 4F in diameter with balloon. The Angioplasty Ring was wound on to the tip of the catheter. The Catheter was inserted into the artery under fluoroscopy. once in place, hot salin (50゚C 10ml) was injected through the Catheter to expand the ring. Under fluoroscopy, the ring was opened immediately by hot salin and fixed in the artery by its own expandability.
12 Angioplasty Rings (ID 5mm, length 5mm, thickness 0.25mm) were implanted in the common iliac artery of dogs. 10/12 rings were patent at 1 year study and 4/4rings were patent at 2 year study. 10 Angioplasty Rings (ID 3mm, length 5mm, thickness 0.15mm) Which will be used for human coronary artery were implanted in the abdominal artery of rabbits. 9/10 rings were patent at 1 month study.
These results show Angioplasty Ring is promising for clinical application.

Report

(4 results)
  • 1989 Annual Research Report   Final Research Report Summary
  • 1988 Annual Research Report
  • 1987 Annual Research Report
  • Research Products

    (16 results)

All Other

All Publications (16 results)

  • [Publications] 杉田洋一: "形状記憶合金(Nitinol) を利用したAngioplasty Ringの開発" 人工臓器. 16. 1407-1410 (1987)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] 杉田洋一: "血管を形状記憶合金で拡張" Modern Medicine. 18. 34-37 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] 杉田洋一: "形状記憶合金・樹脂の応用" 外科. 51. 709-715 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] 高倉宏充: "PTCA後の再狭窄予防を目的とした形状記憶合金によるCoronary Stentの開発" 人工臓器(発表予定).

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Yoichi Sugita, Teruichi Shimomitsu, Takahiko Oku, Shun Murabayashi, Helen E Kambic, Hiroaki Harasaki, Earl Shirey, Leonard Golding and Yukihiko Nose: "Nonsurgical Implantation of a Vascular Ring Prosthesis Using Thermal Shape Memory Ti/Ni Alloy (Nitinol Wire)." Trans. Am. Soc. Artif. Intern.Organs. Vol 32. 30-34 (1986)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Sugita Y., Shimomitsu T., Oku T., Murabayashi S., Harasaki H., Kambic H., Shirey E., Nose Y.: "Development of Angioplasty Ring Using Thermal Shape Memory Ti/Ni Alloy (Nitinol)." Jinkozoki Vol 16 1407-1410, 1987.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Yoichi Sugita, Hiromitsu Takakura, Tatsuta Arai, Hiroaki Harasaki, Helen Kambic, Yukihiko Nose: "Clinical Application of Thermal Shape Memory Alloy and Plastic." Geka Vol 51 709-715, 1989.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Yoichi Sugita: "Expansion of the Artery Using Thermal Shape Memory Alloy." Modern Medicine Vol 18:34-37, 1989.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] 杉田洋一: "形状記憶合金・樹脂の応用" 外科. 51. 709-715 (1989)

    • Related Report
      1989 Annual Research Report
  • [Publications] 高倉宏充: "PTCA後の再狭窄予防を目的とした形状記憶合金によるCoronary Stentの開発" 人工臓器.

    • Related Report
      1989 Annual Research Report
  • [Publications] 杉田洋一: 人工臓器. 18. 188-191 (1988)

    • Related Report
      1988 Annual Research Report
  • [Publications] 杉田洋一: Modern Medicine. 18. 34-37 (1989)

    • Related Report
      1988 Annual Research Report
  • [Publications] 杉田洋一: 日本胸部外科学会雑誌(抄録集). 36. 1850 (1988)

    • Related Report
      1988 Annual Research Report
  • [Publications] 杉田洋一: 日本心臓血管外科学会雑誌.

    • Related Report
      1987 Annual Research Report
  • [Publications] 杉田洋一: 日本外科学会雑誌.

    • Related Report
      1987 Annual Research Report
  • [Publications] 杉田洋一: 日本循環器学会雑誌.

    • Related Report
      1987 Annual Research Report

URL: 

Published: 1987-04-01   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi