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Experimental Study for Control of Total Artificial Heart by Body Activity Sensor Pacemaker.

Research Project

Project/Area Number 62480296
Research Category

Grant-in-Aid for General Scientific Research (B)

Allocation TypeSingle-year Grants
Research Field Thoracic surgery
Research InstitutionFukushima Medical University

Principal Investigator

IWYA Fumio  FUKUSHIMA MEDICAL COLLEGE, Cardiovascular Surgery Associate Professor, 医学部・心臓血管外科, 助教授 (90045758)

Co-Investigator(Kenkyū-buntansha) HAGIWARA Kenichi  FUKUSHIMA MEDICAL COLLEGE, Cardiovascular Surgery Assistant, 心臓血管外科, 助手
ABE Toshifumi  FUKUSHIMA MEDICAL COLLEGE, Cardiovascular Surgery Assistant, 心臓血管外科, 助手 (50145603)
IGARI Tsuguo  FUKUSHIMA MEDICAL COLLEGE, Cardiovascular Surgery Lecturer, 心臓血管外科, 講師 (50045796)
HOSHINO Shunichi  FUKUSHIMA MEDICAL COLLEGE, Cardiovascular Surgery Professor, 心臓血管外科, 教授 (60045630)
丹治 雅博  福島県立医科大学, 第一外科, 副手
高野 光太郎  福島県立医科大学, 第一外科, 副手
星野 俊一  福島県立医科大学, 第一外科, 助教授 (00161547)
Project Period (FY) 1987 – 1989
Project Status Completed (Fiscal Year 1989)
Budget Amount *help
¥6,900,000 (Direct Cost: ¥6,900,000)
Fiscal Year 1989: ¥700,000 (Direct Cost: ¥700,000)
Fiscal Year 1988: ¥2,500,000 (Direct Cost: ¥2,500,000)
Fiscal Year 1987: ¥3,700,000 (Direct Cost: ¥3,700,000)
KeywordsTotal Artificial Heart / Calf / Body Activity Sensor / Pacemaker / Mixed Venous Oxygen Saturation / 駆動制御 / 経皮的酸素飽和度 / 置換型人工心臓 / 圧電式センサー / ペースメーカー / 運動負荷 / 完全人工心臓 / 運動負荷テスト / 圧電センサー
Research Abstract

Pacemaker with body activity sensor and mixed venous oxygen saturation (SvO_2) were evaluated for control of total artificial heart, using calves. There was good correlation between SvO_22 and cardiac output. To evaluate the sensitivity of the pacemaker with body activity sensor which was connected to heart driver as regulator of total artificial heart, the pacemaker was externally attached to the chest wall of a 28-year -old man. Good correlation between intrinsic heart rate and driving rate during treadmill exercise was observed. There have been seven total artificial heart experiments using calves in our Department of Cardiovascular Surgery during the last three years.
Their mean survival period was 4 days and 8 hours. We could not achieve control of total artificial heart driving by pacemaker with body activity sensor because the calves were not well enough to get on the treadmill.
Although we could not obtain good results with animal experiments, we believe that this control system is more physiologically suitable to drive a total artificial heart during exercise.

Report

(4 results)
  • 1989 Annual Research Report   Final Research Report Summary
  • 1988 Annual Research Report
  • 1987 Annual Research Report
  • Research Products

    (9 results)

All Other

All Publications (9 results)

  • [Publications] 岩谷文夫他: "混合静脈血酸素飽和度及び圧電式センサ-を利用した置換型人工心臓の駆動制御" 人工臓器. 18. 611-614 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Fumio Iwaya,et al.: "Current Perspectives on Implantable Devices “Development of a total artificial heart in Japan"" JAI Press Inc., 317 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] 岩谷文夫 他: "混合静脈血酸素飽和度及び圧電式センサ-を利用した置換型人工心臓の駆動制御" 人工臓器. 18. 611-614 (1989)

    • Related Report
      1989 Annual Research Report
  • [Publications] Fumio Iwaya,et al.: "Current Perspectives on Implantable Devices“Development of a total artificial heart in Japan"" JAI Press Inc., 317 (1989)

    • Related Report
      1989 Annual Research Report
  • [Publications] 猪狩次雄: 臨床胸部外科. 8. 307-313 (1988)

    • Related Report
      1988 Annual Research Report
  • [Publications] 岩谷文夫 他: 人工臓器.

    • Related Report
      1988 Annual Research Report
  • [Publications] 岩谷文夫 他: "人工臓器-臨床応用の現況と将来" 日本人工臓器学会, 126-141 (1988)

    • Related Report
      1988 Annual Research Report
  • [Publications] 猪狩次雄他: 臨床胸部外科. (1988)

    • Related Report
      1987 Annual Research Report
  • [Publications] 岩谷文夫他: "人工臓器セミナーテキスト" 日本人工臓器学会, (1988)

    • Related Report
      1987 Annual Research Report

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Published: 1987-04-01   Modified: 2017-10-19  

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