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The influence of degranulation by antigen specific IgG and IgG_4 antibody in nasal allergy patient.

Research Project

Project/Area Number 62480358
Research Category

Grant-in-Aid for General Scientific Research (B)

Allocation TypeSingle-year Grants
Research Field Otorhinolaryngology
Research InstitutionNagoya City University, Medical School

Principal Investigator

ITO Hirotaka  Nagoya city university, Medical school,associate professor, 医学部, 助教授 (60080115)

Co-Investigator(Kenkyū-buntansha) MATSUSHITA Takashi  Nagoya city university, Medical school, assistant, 医学部, 助手 (90181718)
Project Period (FY) 1987 – 1988
Project Status Completed (Fiscal Year 1988)
Budget Amount *help
¥3,000,000 (Direct Cost: ¥3,000,000)
Fiscal Year 1988: ¥1,000,000 (Direct Cost: ¥1,000,000)
Fiscal Year 1987: ¥2,000,000 (Direct Cost: ¥2,000,000)
KeywordsNasal allergy / 脱顆粒 / 好酸球 / アレルギー性鼻炎 / ペルオキシダーゼ / アリルスルファターゼ / アルカリフォスファターゼ / 抗原特異IsG / IgG_4
Research Abstract

Eosinophils are found in the nasal discharge of patients with allergic rhinitis. They are well known to release many kinds of chemical mediators by the antigen challenge. Using anti-peroxidase antibody and Protein A-gold, we try to stain the peroxidase granules in the eosinophils and examine possible influence of the allergic attack and its treatment. From these study, we obtain the result that the granules in the eosinophils change to four types by the attack and the treatment.

Report

(3 results)
  • 1988 Annual Research Report   Final Research Report Summary
  • 1987 Annual Research Report
  • Research Products

    (8 results)

All Other

All Publications (8 results)

  • [Publications] 伊藤博隆,松下隆: Allergy. 9. 332 (1988)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1988 Final Research Report Summary
  • [Publications] 伊藤博隆: 耳鼻咽喉科臨床.

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1988 Final Research Report Summary
  • [Publications] Hirotaka,Ito; Takashi,Matsushita: "Observation on eosinophil's granules in the nasal discharge of patients with nasal allergy" Allergy. 9. 332 (1988)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1988 Final Research Report Summary
  • [Publications] 伊藤博隆;馬場駿吉: 日本扁桃研究会会志. 26. 119-171 (1987)

    • Related Report
      1987 Annual Research Report
  • [Publications] 伊藤博隆: JOHNS. 3. 29-35 (1987)

    • Related Report
      1987 Annual Research Report
  • [Publications] 伊藤博隆: 臨床成人病学. 775-779 (1987)

    • Related Report
      1987 Annual Research Report
  • [Publications] 伊藤博隆: JOHNS. 12. 43-49 (1987)

    • Related Report
      1987 Annual Research Report
  • [Publications] 伊藤博隆: "耳鼻咽喉科領域の看護" 日総研出版, 263 (1987)

    • Related Report
      1987 Annual Research Report

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Published: 1987-04-01   Modified: 2016-04-21  

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