| Project/Area Number |
62570233
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| Research Category |
Grant-in-Aid for General Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Research Field |
Hygiene
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| Research Institution | Kagoshima University |
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Principal Investigator |
MATSUSHITA Toshio Kagoshima University Faculty of Medicine, Professor, 医学部, 教授 (10022790)
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| Co-Investigator(Kenkyū-buntansha) |
AOYAMA Kohji Kagoshima University Faculty of Medicine, Reserch Assistant and Teaching Fellow., 医学部, 助手 (70117472)
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| Project Period (FY) |
1987 – 1988
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| Project Status |
Completed (Fiscal Year 1988)
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| Budget Amount *help |
¥1,500,000 (Direct Cost: ¥1,500,000)
Fiscal Year 1988: ¥600,000 (Direct Cost: ¥600,000)
Fiscal Year 1987: ¥900,000 (Direct Cost: ¥900,000)
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| Keywords | Okra (Hibiscus esculentus L.) / Occupational dermatoses / Patch test / 皮膚アレルギー |
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| Research Abstract |
Epidemiological surveys on occupational dermatoses in farmers growing okra (Hibiscus esculentus L.) and related experimental studies were undertaken.
From the field survey over a period of two years, the incidence rates of dermatoses suffering from okra growing were considerably high (46.3-53.9%), and if workers are engaged in the work without effective protective gloves and clothes, nearly all persons are assumed to be suffered from dermatoses following okra farming.
Among 118 subjects tested, 16(13.6%) were reacted with okra components by patch testing and okra workers showed relatively higher positive rate (15.7%) than the others (6.9%).
By experimental studies using guinea pigs, the components of okra indicated relatively high potency of primary irritating reactions, but not the allergic and phototoxic reaction.
Based on those data with epidemiological observations, the mechanism of dermatoses due to okra working were estimated to be consist of the following three effects; (1) mechanical reactions caused by direct contact to a large quality of okra, (2) primary irritating reactions to okra components, and (3) allergic reaction with okra components.
Some proposals for effective preventive procedures against okra dermatoses were also examined and discussed.
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