| Project/Area Number |
62570735
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| Research Category |
Grant-in-Aid for General Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Research Field |
Urology
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| Research Institution | TOHO UNIVERSITY SCHOOL OF MEDICINE |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
TAKANAMI Masaharu TOHO UNIVERSITY SCHOOL OF MEDICINE, 医学部, 助手 (60163226)
MIURA Kazukiyo TOHO UNIVERSITY SCHOOL OF MEDICINE, 医学部, 講師 (00057697)
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| Project Period (FY) |
1987 – 1988
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| Project Status |
Completed (Fiscal Year 1988)
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| Budget Amount *help |
¥1,400,000 (Direct Cost: ¥1,400,000)
Fiscal Year 1988: ¥500,000 (Direct Cost: ¥500,000)
Fiscal Year 1987: ¥900,000 (Direct Cost: ¥900,000)
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| Keywords | Impotence / Nocturnal penile tumescence (NPT) / Erectiometer / Questionnaire regarding sexual function / Side effect of drugs / エレクチオメーター / 性機能調査表 / 薬物の副作用 / 抗男子ホルモン / Nocturnal penile tumescence:NPT / 抗男性ホルモン / 男子性機能障害 / 勃起機能障害 / 射精機能障害 / 勃起機能検査 |
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| Research Abstract |
WITH THE PURPOSE OF DETERMINING OBJECTIVELY THE INFLUENCE OF DRUGS EXERTED ON THE MALE SEXUAL FUNCTION, STUDY HAS BEEN MADE WHETHER CORRECT JUDGEMENT OF DRUGS IS POSSIBLE OR NOT BY MEANS OF QUESTIONNAIRE REGARDING SEXUAL FUNCTION BY HAVING THE PATIENTS WITH PROSTATIC HYPERTROPHY ENTER THE QESTIONNAIRE BEFORE AND AFTER ADMINISTERING TO THEM ANTIANDROGENS (CHLORMADINONE ACETATE OR ALLYLESTRENOL) WHICH WERE IDENTIFIED PRELIMINARILY TO EXERT INFLUENCE ON THE MALE SEXUAL FUNCTION. AS A RESULT, IT WAS FOUND THAT THE QUESTIONNAIRE REGARDING SEXUAL FUNCTION USED THIS TIME PROVIDES GOOD JUDGEMENT ON THE INFLUENCE OF DRUGS EXERTED ON THE MALE SEXUAL FUNCTION. HOWEVER, THE TEST THROUGH QUESTIONNAIRE IS PROBLEMATIC IN THE ASPECT OF OBJECTIVITY, FOR WHICH IT WAS DECIDED THAT ERECTILE CONDITION WAS RECORDED BY AN ERECTIOMETER. HOWEVER, THE ERECTIOMETER POSES PROBLEMS THAT SUSTAINED TIME AND FREQUENCY OF ERECTION CAN NOT BE MEASURED, THOUGH IT CAN RECORD THE MAXIMUM EXTENTION OF THE PENILE DIAMETER AMONG CASES. THEREFORE, WE HAVE DEVELOPED A SUBMINIATURE ERECTILE RECORDING APPARATUS BY THE USE OF IC MEMORY CARD WHICH CAN BE LENT OUT TO PATIENTS AND IS MAKING ASSESMENT THE INFLUENCE EXERTED ON NOCTURNAL PENILE TUMESCENCE(NPT) WHEN DRUGS HAVE BEEN ADMINISTERED FOR MORE THAN DEFINITE PERIODS. THIS RECORDER IS VERY EASY FOR ATTACHMENT AND ALSO CONVENIENT FOR MAKING ANALYSIS OF THE DATA RECORDED ON IC MEMORY CARD, FROM WHICH IT IS CONSIDERED THAT OBJECTIVE JUDGEMENT OF DRUG INFLUENCE ON NPT IS POSSIBLE WITH THIS PAPPARATUS.
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