• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

細胞複製の分子遺伝学的展開

Research Project

Project/Area Number 62615006
Research Category

Grant-in-Aid for Scientific Research on Priority Areas

Allocation TypeSingle-year Grants
Research InstitutionOsaka University

Principal Investigator

吉川 寛  大阪大学, 医学部, 教授 (70019876)

Co-Investigator(Kenkyū-buntansha) 堀田 康雄  名古屋大学, 理学部, 教授 (30190218)
豊島 久真男  東京大学, 医科学研究所, 教授 (90029760)
松原 謙一  大阪大学, 細胞工学センター, 教授 (20037394)
関口 睦夫  九州大学, 医学部, 教授 (00037342)
石浜 明  国立遺伝学研究所, 分子遺伝研究系, 教授 (80019869)
Project Period (FY) 1987
Project Status Completed (Fiscal Year 1987)
Budget Amount *help
¥16,000,000 (Direct Cost: ¥16,000,000)
Fiscal Year 1987: ¥16,000,000 (Direct Cost: ¥16,000,000)
Keywords細胞複製 / 染色体 / 細胞周期 / 総括班 / 公開シンポジウム / ワークショップ
Research Abstract

本重点研究は細胞複製を分子遺伝学の最新技術を用いて総合的に解析するため, 1)染色体の分子機構, 2)染色体の機能領域, 3)染色体の複製機構, 4)細胞生産装置の複製, 5)細胞分裂と細胞周期の5班を組織した. 本総括班は各班の代表者と9名の外部班員で構成し, 各班の個別な研究を推進すると共に相互の課題の関係を明らかにし, 総合化を目指す共同研究の発表を目的とした. 3年計画の初年度である本年は班員及び班間の交流を通じて正しい課題の設定と総合的研究を推進する体制を作るため, 以下の活動を行った.
1. 総括班会議, 第1回(6月)に, 合同班会議, ワークショップを中心とする年間活動計画を立案し, 第2回(63年2月)で総括評価した. 全体的に当初の計画が順調に遂行されていると評価され, 特に外部委員から,原核生物における体系的な研究によって, 複雑な生命現象である細胞複製の解明が確実に前進しており, 真核生物の諸現象の研究の有効な指針となると指摘を受けた.
2. 公開シンポジウム, 「細胞複製をテーマに行った. 故広田幸敬氏を中心とした細胞複製の研究の歴史を背景に, 現在の研究と将来の展望が語られ, 150名余の聴衆に感銘を与えた啓豪的講演会として成功した.
3. 合同班会議, 染色体と細胞を2つの柱に分けて開催し, 研究の目的, 意義, 将来展望を中心に報告, 討論し, 班員相互の交流を深めた.
4. ワークショップ:「細胞周期」主催し, 染色体に関する「組換え」, 「複製開始」「分子構築」の3つを共催した. それぞれ50〜80名の参加者が合宿し, 熱心に討討した. 特に主催した細胞周期は分子遺伝学と生化学の協力によって, 本格的な研究が推進されるべき時期であることの認識を深め, 今後経続的に開催することによって次期重点研究への発展の可能性を検討することとした.
5. その他, サーキュラーの発行(3回)とDNAクローンバンクの作成と供給に関する研究支援事業を開始した.

Report

(1 results)
  • 1987 Annual Research Report
  • Research Products

    (50 results)

All Other

All Publications (50 results)

  • [Publications] L.Andrup et al.: J.Bacteriol.IN PRESS. (1988)

    • Related Report
      1987 Annual Research Report
  • [Publications] S.Moriya et al.: Genetics and Biotechnology of Bacilli. 2. (1988)

    • Related Report
      1987 Annual Research Report
  • [Publications] 吉川 寛, 他: 代謝. 24. 3-13 (1987)

    • Related Report
      1987 Annual Research Report
  • [Publications] T.Iino et al.: J.Gen.Microbiol.133. 779-782 (1987)

    • Related Report
      1987 Annual Research Report
  • [Publications] K.Ohnishi et al.: J.Bacteriol.169. 1485-1488 (1987)

    • Related Report
      1987 Annual Research Report
  • [Publications] M.Tsuda et al.: Mol.Gene.Genet.210. 270-276 (1987)

    • Related Report
      1987 Annual Research Report
  • [Publications] Fujita,N.: J.Biol.Chem.262. 1855-1859 (1987)

    • Related Report
      1987 Annual Research Report
  • [Publications] Fujita,N.: Mol.Gen.Genet.210. 5-9 (1987)

    • Related Report
      1987 Annual Research Report
  • [Publications] Glass,R.E.: Mol.Gen.Genet.210. 1-4 (1987)

    • Related Report
      1987 Annual Research Report
  • [Publications] Ishihama,A.: Proteins:Structure,Function and Genetics. 2. 42-53 (1987)

    • Related Report
      1987 Annual Research Report
  • [Publications] Ishihama,A.: Mol.Gen.Genet.206. 185-191 (1987)

    • Related Report
      1987 Annual Research Report
  • [Publications] Nomura,T.: J.Mol.Biol.197. 659-670 (1987)

    • Related Report
      1987 Annual Research Report
  • [Publications] Jun Sukegawa et al.: Mol.Cell.Biol.7. 41-47 (1987)

    • Related Report
      1987 Annual Research Report
  • [Publications] Yuji Yamanashi et al.: Mol.Cell.Biol.4. 237-243 (1987)

    • Related Report
      1987 Annual Research Report
  • [Publications] Takashi Kadowaki et al.: Biochem.Biophys.Res.Commun.144. 699-704 (1987)

    • Related Report
      1987 Annual Research Report
  • [Publications] Kenzaburo Tani et al.: Biochem.Biophys.Res.Commun.143. 431-438 (1987)

    • Related Report
      1987 Annual Research Report
  • [Publications] Mikiharu Fukui et al.: Mol.Cell.Biol.7. 1776-1781 (1987)

    • Related Report
      1987 Annual Research Report
  • [Publications] Sadaaki Kawai et al.: J.Virol.61. 1665-1669 (1987)

    • Related Report
      1987 Annual Research Report
  • [Publications] H.Stern et al.: Monograph "Meiosis" ed.by Moens,Acade.Press,New York. 303-331 (1987)

    • Related Report
      1987 Annual Research Report
  • [Publications] S.Tabata et al.: Tokai J.Exp.Clin.Med.11. 395-401 (1987)

    • Related Report
      1987 Annual Research Report
  • [Publications] M.Sekiguchi et al.: Trends in Genetics. 3. 51-54 (1987)

    • Related Report
      1987 Annual Research Report
  • [Publications] K.Ishizaki et al.: Mutat.Res.184. 121-128 (1987)

    • Related Report
      1987 Annual Research Report
  • [Publications] K.Takano et al.: J.Mol.Biol.(1988)

    • Related Report
      1987 Annual Research Report
  • [Publications] T.Nakamura et al.: J.Mol.Biol.(1988)

    • Related Report
      1987 Annual Research Report
  • [Publications] Y.Onuki et al.: Virology. 156. 163-166 (1987)

    • Related Report
      1987 Annual Research Report
  • [Publications] T.Kimura et al.: B.B.A.908. 285-292 (1987)

    • Related Report
      1987 Annual Research Report
  • [Publications] J.Kato et al.: J.Jpn.Cancer Research. 78. 1354-1362 (1987)

    • Related Report
      1987 Annual Research Report
  • [Publications] Y.Hirota et al.: Mol.Cell.Biol.

    • Related Report
      1987 Annual Research Report
  • [Publications] F.Hirota et al.: Advances in Cancer Research. 49. 223-264 (1987)

    • Related Report
      1987 Annual Research Report
  • [Publications] Takashi Sugimura: Trends in Pharmacological Sciences.

    • Related Report
      1987 Annual Research Report
  • [Publications] K.Yamane et al.: J.Biol.Chem.262. 2358-2362 (1987)

    • Related Report
      1987 Annual Research Report
  • [Publications] T.Suzuki et al.: J.Bacteriol.169. 2523-2528 (1987)

    • Related Report
      1987 Annual Research Report
  • [Publications] S.Matsuyama et al.: J.Mol.Biol.195. 847-853 (1987)

    • Related Report
      1987 Annual Research Report
  • [Publications] H.Aiba et al.: J.Bacteriol.169. 3007-3012 (1987)

    • Related Report
      1987 Annual Research Report
  • [Publications] D.-S.Choi et al.: J.Biochem.102. 975-983 (1987)

    • Related Report
      1987 Annual Research Report
  • [Publications] T.Mizuno et al.: J.Biol.Chem.263. 1008-1012 (1988)

    • Related Report
      1987 Annual Research Report
  • [Publications] Ryo Hanai et al.: Journal of chromatography. 394. 273-278 (1987)

    • Related Report
      1987 Annual Research Report
  • [Publications] Shun-ichi Kidokoro et al.: Biopolymers. 26. 213-229 (1987)

    • Related Report
      1987 Annual Research Report
  • [Publications] Ichiro Oohara et al.: J.Mol.Biol.196. 389-397 (1987)

    • Related Report
      1987 Annual Research Report
  • [Publications] Ichiro Oohara et al.: J.Mol.Biol.196. 399-411 (1987)

    • Related Report
      1987 Annual Research Report
  • [Publications] Ryo Hanai et al.: FEBS LETTERS,. 226. 247-249 (1987)

    • Related Report
      1987 Annual Research Report
  • [Publications] H.Suzuki et al.: Jounal of Bacteriology. 169. 891-893 (1987)

    • Related Report
      1987 Annual Research Report
  • [Publications] N.Kusukawa et al.: Mol.Gen.Genet.208. 365-372 (1987)

    • Related Report
      1987 Annual Research Report
  • [Publications] 平賀 壮太: 細胞工学. 6. 37-49 (1987)

    • Related Report
      1987 Annual Research Report
  • [Publications] Shoji Mizushima: "細胞工学 別冊2" 東京化学同人, 12 (1987)

    • Related Report
      1987 Annual Research Report
  • [Publications] Shigeyuki Ichihara et al.: "現代化学 増刊10" 東京化学同人, 17 (1987)

    • Related Report
      1987 Annual Research Report
  • [Publications] Ishihama,A.: "RNA Polymerase and the Regulation of Transcription" Elsevier Science Publ.,New York, 494 (1987)

    • Related Report
      1987 Annual Research Report
  • [Publications] 石浜 明: "生命科学の新しい展開を求めて" 出版科学総合研究所,東京, 299 (1987)

    • Related Report
      1987 Annual Research Report
  • [Publications] Kuamo Tyoshima et al.: "Advances in Virus Research" Eds.K.Maramorosch,F.A.Murphy,A.J. Shatkin,Academic Press,Inc.Florida, 97-127 (1987)

    • Related Report
      1987 Annual Research Report
  • [Publications] Tadashi Yamamoto et al.Eds.M.I.Greene and T.Hamaoka: "Induction and recoqnition of the transformed cell" Plenum Publishing Corporation,New York, 93-110 (1987)

    • Related Report
      1987 Annual Research Report

URL: 

Published: 1987-04-01   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi