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Removal of Solute-Free Water from Diluted Blood and Regeneration of Dialysate by Membrane Distillation

Research Project

Project/Area Number 62850162
Research Category

Grant-in-Aid for Developmental Scientific Research

Allocation TypeSingle-year Grants
Research Field 化学工学
Research InstitutionWaseda University

Principal Investigator

SAKAI Kiyotaka  Waseda University, Professor, 理工学部, 教授 (00063727)

Co-Investigator(Kenkyū-buntansha) TAKESAWA Shingo  Yokohama Dai-ichi Hospital, Manager of Lab., 研究室長 (30171630)
Project Period (FY) 1987 – 1989
Project Status Completed (Fiscal Year 1989)
Budget Amount *help
¥10,900,000 (Direct Cost: ¥10,900,000)
Fiscal Year 1989: ¥1,200,000 (Direct Cost: ¥1,200,000)
Fiscal Year 1988: ¥2,400,000 (Direct Cost: ¥2,400,000)
Fiscal Year 1987: ¥7,300,000 (Direct Cost: ¥7,300,000)
KeywordsPolytetrafluoroethylene / Water Vapor Permeability / Temperature Polarization / Concentration Polarization / Ethylene Glycol / Bovine Blood / Bovine Plasma / Tortuosity
Research Abstract

We have tried removal of solute-free water from bovine blood and regeneration of dialysate by membrane distillation which have the advantages of high flux and outstanding selectivity at lower temperatures. Results are listed below: 1. Water vapor permeability for pure water is measured with a temperature controlled stirred cell. Heat transfer coefficients of both sides of PTFE (polytetrafluoroethylene) membranes are calculated by conventional heat transfer model. Water vapor permeability of the membrane for pure water is linearly proportional to porosity divided by membrane thickness. The tortuosity of the membrane is calculated to be 1.27 from the slope of a linear plot of water vapor permeability against porosity divided by membrane thickness. 2. Water vapor permeate flux data is determined with the temperature controlled stirred cell to clarify effects of temperature and concentration polarization on water vapor permeability in membrane distillation . Temperature and concentration at membrane surfaces is evaluated based on heat and mass transfer models. Wall temperature at warm compartment increases with stirring speed while wall concentration decreases with stirring speed. 3. Ions are impermeable to the PTFE membranes, demonstrating the possibility of complete regeneration of discarded dialysate. 4. Techniques of air-liquid membrane distillation are capable of removing solute-free water from bovine blood. Heat efficiency of air-liquid membrane distillation with 3.22gmol/kg ethylene glycol solution at an air flow rate of 40.4 I/min is calculated to be 75% and that of liquid-liquid membrane distillation at a stirring speed of 16.7s^<-1> to be 55%. Techniques of air-liquid membrane distillati are superior to those of liquid-liquid membrane distillation with respect to heat efficiency.

Report

(3 results)
  • 1989 Annual Research Report   Final Research Report Summary
  • 1988 Annual Research Report
  • Research Products

    (16 results)

All Other

All Publications (16 results)

  • [Publications] Sakai,K.: "Extraction of solute-free water from blood by membrane distillation" Trans.Am.Soc.Artif.Intern.Organs. 32. 397-400 (1986)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Sakai,K.: "Effect of temperature and concentration polarization on water vapour permeability for blood in membrane distillation" Chem.Eng.J.38. B33-B39 (1988)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Sakai, K.: "Effect of temperature and concentration polarization on water vapor permeability for blood in membrane distillation" Chem.Eng.J.38. 33-39 (1988)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Sakai, K.: "Extraction of solute-free water from blood by membrane distillation" Trans.Am.Soc.Artif.Intern.Organs. 32. 397-400 (1986)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Okada,M.: "Effects of zeta potential on the permeability of dialysis membranes to inorganic phosphate" Trans.Am.Soc.Artif.Intern.Organs. 35. 320-322 (1989)

    • Related Report
      1989 Annual Research Report
  • [Publications] Ohmura,T.: "A new method of determining the solute permeability of hollow-fiber dialysis membranes by means of laser lights traveling along optic fibers" Trans.Am.Soc.Artif.Intern.Organs. 35. 601-603 (1989)

    • Related Report
      1989 Annual Research Report
  • [Publications] Sakai,K: "Technical determination of optimal dimensions of hollow fibre membranes for clinical dialysis" Nephrol.Dial.Transplant.4. 73-77 (1989)

    • Related Report
      1989 Annual Research Report
  • [Publications] Sakai,K.: "Structure and permeability of dialysis membrane sterilized by various methods" J.Biomater.Appl.4. 71-101 (1989)

    • Related Report
      1989 Annual Research Report
  • [Publications] Sakai,K.: "Low-temperature plasma separation by cross-flow filtration with microporous glass membrane" I&EC Research. 28. 57-64 (1989)

    • Related Report
      1989 Annual Research Report
  • [Publications] Ozawa,K.: "Technical evaluation of newly-developed inorganic membranes for plasma fractionation" Int.J.Artif.Organs. 12. 195-198 (1989)

    • Related Report
      1989 Annual Research Report
  • [Publications] Sakai,K: Chem.Eng.J. 38. B33-B39 (1988)

    • Related Report
      1988 Annual Research Report
  • [Publications] Sakai,K.: J.Mem.Sci.10. 3-17 (1987)

    • Related Report
      1988 Annual Research Report
  • [Publications] Takesawa,S.: Nephrol.Dial.Transplant.1. 254-257 (1987)

    • Related Report
      1988 Annual Research Report
  • [Publications] Takesawa,S.: Trans.ASAIO. 33. 584-587 (1987)

    • Related Report
      1988 Annual Research Report
  • [Publications] Sakai,K.: Trans.ASAIO. 32. 397-400 (1986)

    • Related Report
      1988 Annual Research Report
  • [Publications] Sakurai,H: Trans.ASAIO. 32. 410-413 (1986)

    • Related Report
      1988 Annual Research Report

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Published: 1987-04-01   Modified: 2016-04-21  

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