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Developmental study for the animal holding facility with fully-enclosed life support system

Research Project

Project/Area Number 62870007
Research Category

Grant-in-Aid for Developmental Scientific Research

Allocation TypeSingle-year Grants
Research Field 環境生理学(含体力医学・栄養生理学)
Research InstitutionResearch Institute of Environmental Medicine, Nagoya University

Principal Investigator

WATANABE Satoru (1988-1989)  Research institute of Environmental Medicine, Professor, 環境医学研究所, 教授 (00021361)

渡辺 悟 (1987)  名古屋大学, 環境医学研究所, 教授

Co-Investigator(Kenkyū-buntansha) MATSUMURA Hiroyuki  Kawasaki Heavy Industries, Ltd., Director of Section, 技術研究所, 室長
OZAKI Hisaki  Faculty of Education, Ibaragi University, Associate Professor, 教育学部, 助教授 (40092514)
YAMASHITA Masamichi  Institute of Space and Astronautical Science, Associate Professor, 助教授 (60107480)
TANAKA Masafumi  Research Institute of Environmental Medicine, Nagoya University, Assistant, 環境医学研究所, 助手 (30197470)
KIDA Mitsuo  Research Institute of Environmental Medicine, Nagoya University, Associate Profe, 環境医学研究所, 助教授 (80023654)
須藤 秀雄  川崎重工業, 航空機技術本部宇宙機器室, 係長
三木 三省  川崎重工業, 宇宙開発室, 室長
森 滋夫  名古屋大学, 環境医学研究所, 助教授 (00023656)
Project Period (FY) 1987 – 1989
Project Status Completed (Fiscal Year 1989)
Budget Amount *help
¥11,100,000 (Direct Cost: ¥11,100,000)
Fiscal Year 1989: ¥2,100,000 (Direct Cost: ¥2,100,000)
Fiscal Year 1988: ¥3,000,000 (Direct Cost: ¥3,000,000)
Fiscal Year 1987: ¥6,000,000 (Direct Cost: ¥6,000,000)
KeywordsSpace life science / fully-enclosed environment / life support system / telescience / data packaging technique / removal technique of noxious gas / removal of NH / telemetering of physiological signals / 宇宙実験用閉鎖環境生命維持装置 / 微生物分析 / アンモニア処理 / バイオテクノロジー / 超小型テレメータ / データ圧縮法
Research Abstract

The most important conditions to be prepared for the research animal holding facility (RAHF) with a fully enclosed life support system are given by following items; to control the composition, temperature, humidity, and pressure of the air, to remove trace contaminants/odors in the air and to supply foods and water, waste management and so forth. The RAHF designed in our laboratory was controlled automatically such conditions. A main theme in the first year (1987) narrowed down to the removal of ammonium (NH ) and CO in the air which originated from animal urine and feces as well as from remnants of foods. A method used in this study was provided a shower chamber in which NH dissolved into flashing water. When PH and temperature of flashing water is controlled, some sort of bacteria may proliferate and may resolve or subsist on NH . Water soluble trace contaminants were resolved in flashing water. Another noxious gas of CO was easily able to oxidize to CO . Then, noxious substance of c … More ontaminants in the air were almost made clean in the RAHF. Environmental conditions were also assessed by animal behavior and physiological data. In the second year (1988) the physiological monitoring by using telemeter system which recorded ECG and body temperature, was carried out in parallel with measurements of the number of wheel rotation as a behavioral index and of oxygen consumption and body weight as a metabolic index. In the last year (1989) the long term (3 months) breeding experiment was conducted. As the results, an estimated NH concentration in the flashing water was well corresponding with the consumption of H SO until 2 months, but thereafter H SO consumption was stopped in spite of keeping the low level of NH concentration in the air and also in the flashing water. This fact means that NH as a livestock of bacteria may balance with occurrence of NH4 from urine and feces. After 3 months results of gas analysis showed the RAHF to keep trace contaminants in low range, and physiological data also testified to maintain a good environmental conditions which were habitable for hamsters. Less

Report

(3 results)
  • 1989 Annual Research Report   Final Research Report Summary
  • 1988 Annual Research Report
  • Research Products

    (42 results)

All Other

All Publications (42 results)

  • [Publications] 須藤秀雄: "宇宙搭載・小動物用閉鎖式生命維持装置の開発ーその1" 名古屋大学環境医学部研究所年報. 37. 15-21 (1986)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] 渡邉悟: "宇宙実験用動物飼育装置の開発" Proceedings of The Fourth Space Utilization Symposium. 148-151 (1987)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] 須藤秀雄: "宇宙搭載・小動物用閉鎖式生命維持装置の開発ーその2;BBMの試作" 名古屋大学環境医学研究所年報. 39. 33-37 (1988)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] 田中正文: "宇宙実験用閉鎖環境生命維持装置でのハムスタ-の活動量の変化" 第5回宇宙利用シンポジウムプロシ-ディング. 64-68 (1988)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] 山田弘文: "宇宙ステ-ション用動物実験装置の開発ー第一報・地上機能モデルの試作ー" 川崎重工技報. 100. 61-73 (1988)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] T.Shoji: "Developments of Advanced Research Animal Holding Facility(RAHF)for Space Station:I.Developments of Functional Madel." Biological Sciences in Space. 3. 16-24 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] M.Tanaka: "Developments of Advanced Research Animal Holding Facility(RAHF)for Space Station:II.Physiological and Behavioral changes of Golden hamsters in the Fully Enclosed Environmental Life Support System." Biological Sciences in Space. 3. 25-30 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] M.Tanaka: "Phsiological and Behavioral Changes Golden Hamsters in the Fully Enclosed Environmental Life Support System." Environmental Medicine.

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] T.Shoji: "Trace contaminats/oders in the breadboad model(BBM) of improved research animal holding facility(RAHF)" Environmental Medicine.

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] T.Ueda: "Three months duration animal experiment under fully-enclosed environment with RAHF BBM." Proceedings of the 17th ISTS,Tokyo. (1990)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] H.Sudoh: "Biological Sciences in Spase 1986(Proc.of lntern.Symp.on Biol.Sci.in Space.Nagoya)" Myu.Research, 8 (1987)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] 渡邉悟: "宇宙実験用閉鎖環境生命維持装置の開発 昭和61・62年度文部省民間との共同研究報告書" 66 (1988)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] H. Sudoh, H. Matsumura, S. Kanda, S. Watanabe, S. Takagi: "Closed ECLSS for space animal research facility. (in Japanese)" Annals of The Research Institute of Environmental Medicine, Nagoya University. 37. 15-21 (1986)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] H. Sudoh, H. Matsumura, K. Murao, S. Watanabe, M. Kida, S. Takagi: "The development of an improved research animal holding facility - trace contaminants/odors experiments with functional model." "Biological Sciences in Space 1986", eds., S. Watanabe, G. Mitarai, S. Mori, Myu Research, Tokyo. 357-364 (1987)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] S. Watanabe, M. Kida, M. Tanaka, S. Mori, S. Takagi, H. Sudoh, H. Matsumura, K. Murtao: "Developmental studies of animal holding facility for space experiments.(in Japanese)" Proceedings of The fourth Space Utilization Symposium. 148-151 (1987)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] S. Watanabe: "Development of animal holding facility with fully-enclosed life support system for space experiments. (in Japanese)" Report of the collaboration project with the private organization of the Ministry of Education, Science and Culture, Japan 1988/1989.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] H. Sudoh, R. Sakata, H. Matsumura, K. Murao, S. Watanabe, M. Kida, M. Tanaka, S. Takagi: "The development of an improved research animal holding facility - Development of a bread-board model. (in Japanese)" Annals of The Research Institute of Environmental Medicine, Nagoya University. 39. 33-37 (1988)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] M. Tanaka, S. Watanabe, M. Kida, S. Takagi, A. Takabayashi, H. Matsumura, H. Sudoh: "Changes of activity of hamsters in the animal holding facility with fully-enclosed life support system. (in Japanese)" Proceedings of The Fifth Space Utilization Symposium. 64-68 (1988)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] H. Yamada, H. Sudoh, R. Sakata, Y. Nomura, T. Kurose, H. Matsumura, T. Shoji, K. Murao: "Development of advanced research animal holding facility (RAHF) for space station - first report: development of functional model. (in Japanese)" KHI Technical Review. 100. 61-73 (1988)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] T. Shoji, H. Matsumura, H. Sudoh, S. Watanabe: "Developments of advanced Research animal holding facility (RAHF) for space station: I. Developments of functional model." Biological Science in Space. 3 (1). 16-24 (1989)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] M. Tanaka, H. Matsumura, S. Watanabe, Y. Tadokoro: "Developments of advanced research animal holding facility (RAHF) for space station: II Physiological and behavioral changes of golden hamsters in the fully-enclosed environmental life support system." Biological Sciences in Space. 3 (1). 25-30 (1989)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] M. Tanaka, S. Watanabe, H. Matsumura: "Physiological and behavioral changes of golden hamsters in the fully-enclosed environmental life support system." Environmental Medicine.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] T. Shoji, H. Matsumura, H. Sudoh, T. Ueda, H. Yamada, S. Watanabe: "Trace contaminants/odors in the breadboard model (BBM) of improved research animal holding facility (RAHF)." Environmental Medicine.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] T. Ueda, H. Sudoh, H. Yamada, T. Shoji, S. Hatakeyama, S. Watanabe, M. Kida, M. Tanaka, S. Takagi: "Three months duration animal experiment under fully-enclosed environment with RAHF BBM." Proceedings of the 17th ISTS, Tokyo, 1990.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] 須藤秀雄: "宇宙搭載・小動物用閉鎖式生命維持装置の開発ーーその1" 名古屋大学環境医学研究所年報. 37. 15-21 (1986)

    • Related Report
      1989 Annual Research Report
  • [Publications] 渡邉悟: "宇宙実験用動物飼育装置の開発" Proceedings of The Fourth Space Utilization Symposium. 148-151 (1987)

    • Related Report
      1989 Annual Research Report
  • [Publications] 須藤秀雄: "宇宙搭載・小動物用閉鎖式生命維持装置の開発ーーその2;BBMの試作" 名古屋大学環境医学研究所年報. 39. 33-37 (1988)

    • Related Report
      1989 Annual Research Report
  • [Publications] 田中正文: "宇宙実験用閉鎖環境生命維持装置でのハムスタ-の活動量の変化" 第5回宇宙利用シンポジウムプロシ-ディング. 64-68 (1988)

    • Related Report
      1989 Annual Research Report
  • [Publications] 山田弘文: "宇宙ステ-ション用動物実験装置の開発ーー第一報・地上機能モデルの試作ーー" 川崎重工技報. 100. 61-73 (1988)

    • Related Report
      1989 Annual Research Report
  • [Publications] T.Shoji: "Developments of Advanced Research Animal Holding Facility(RAHF)for Space Station:I.Developments of Functional Model." Biological Sciences in Space. 3. 16-24 (1989)

    • Related Report
      1989 Annual Research Report
  • [Publications] M.Tanaka: "Developments of Advanced Research Animal Holding Facility(RAHF)for Space Station:II.Physiological and Behavioral changes of Golden hamsters in the Fully Enclosed Environmental Life Support System." Biological Sciences in Space. 3. 25-30 (1989)

    • Related Report
      1989 Annual Research Report
  • [Publications] M.Tanaka: "Phsiological and Behavioral Changes of Golden Hamsters in the Fully Enclosed Environmental Life Support System." Environmental Medicine.

    • Related Report
      1989 Annual Research Report
  • [Publications] T.Shoji: "Trace contaminats/oders in the breadboad model(BBM)of improved research animal holding facility(RAHF)" Environmental Medicine.

    • Related Report
      1989 Annual Research Report
  • [Publications] H.Sudoh: "Biological Sciences in Space 1986(Proc.of Intern.Symp.on Biol.Sci.in Space,Nagoya)" Myu. Research, 8 (1987)

    • Related Report
      1989 Annual Research Report
  • [Publications] 渡邉悟: "宇宙実験用閉鎖環境生命維持装置の開発 昭和61・62年度文部省民間との共同研究報告書" 66 (1988)

    • Related Report
      1989 Annual Research Report
  • [Publications] 須藤秀雄: 名古屋大学環境医学研究所年報. 37. 15-21 (1986)

    • Related Report
      1988 Annual Research Report
  • [Publications] H.Sudoh: Biological Sciences in Space 1986(Proc.of Intern.Symp.on Biol.Sci.in Space,Nagoya). 357-364 (1987)

    • Related Report
      1988 Annual Research Report
  • [Publications] 渡邉悟: Proceedings of The Fourth Space Utilization Symposium. 148-151 (1987)

    • Related Report
      1988 Annual Research Report
  • [Publications] 須藤秀雄: 名古屋大学環境医学研究所年報. 39. 33-37 (1988)

    • Related Report
      1988 Annual Research Report
  • [Publications] 田中正文: 第5回宇宙利用シンポジウムプロシーディング. 64-68 (1988)

    • Related Report
      1988 Annual Research Report
  • [Publications] 田中正文: 宇宙航空環境医学. (1988)

    • Related Report
      1988 Annual Research Report
  • [Publications] 松村宏之: 宇宙生物科学vol,2 Suppl. 2. 95-96 (1988)

    • Related Report
      1988 Annual Research Report

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Published: 1987-04-01   Modified: 2016-04-21  

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