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The study of the origin of the polymorphism of actin filament assembly and its physiological functions

Research Project

Project/Area Number 63044066
Research Category

Grant-in-Aid for Overseas Scientific Survey.

Allocation TypeSingle-year Grants
SectionJoint Research
Research InstitutionKyoto University

Principal Investigator

ITO Tadanao  Associate Professor, Faculty of Science, Kyoto University, 理学部, 助教授 (90093187)

Co-Investigator(Kenkyū-buntansha) THOMAS Stoss  ハーバード医科大学, 教授
KEN Zaner  ハーバード医科大学, 助教授
SATO Satoshi  Associate Professor, Faculty of Science, Kyoto University, 理学部, 助手 (30183049)
STOSSEL Thomas  Professor, Harvard Medical School
ZANER Ken  Associate Professor, Harvard Medical School
Project Period (FY) 1988 – 1989
Project Status Completed (Fiscal Year 1989)
Budget Amount *help
¥3,600,000 (Direct Cost: ¥3,600,000)
Fiscal Year 1989: ¥1,800,000 (Direct Cost: ¥1,800,000)
Fiscal Year 1988: ¥1,800,000 (Direct Cost: ¥1,800,000)
KeywordsActin Filament / Polymorphism of Assembly Structures / Phase Diagram / Osmoelastic Coupling / Cytoskeleton / Osmotic Pressure / Volume Regulation of Cell / Calcium
Research Abstract

The study supported by this grant is divided into four parts as follows. 1 The analysis of bundle formation of actin filaments caused by the osmoelastic coupling. 2 The analysis of liquid-crystalline phase of actin filaments. 3 Determination of phase diagram of actin filament solution. 4 Role of the cytoskeletal structure of non-muscle cell constructed by actin filaments and ABP on the response to the osmotic stress.

Report

(1 results)
  • 1989 Final Research Report Summary
  • Research Products

    (6 results)

All Other

All Publications (6 results)

  • [Publications] 鈴木厚: "Osmoelastic Coupling in Biological Structures:Formation of Parallel Bundles of Actin Filaments in a Crystalline-like Structure Caused by Osmotic Stress" Biochemistry. 28. 6513-6518 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] 鈴木厚: "Formation of Liquid Crystalline Phase of Actin Filament Solutions and its Dependence on Filament Length" Biophys.J.

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] 伊藤忠直: "Regulation of Osmotic Stress-induced Water Flow by the Network of F-actin Crosslinked by Actin Binding"

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Atsushi Suzuki: "Osmoelastic Coupling in Biological Structures: Formation of Parallel Bundles of Actin Filaments in a Crystalline-like Structure Caused by Osmotic Stress" Biochemistry. 28. 6513-6518 (1989)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Atsushi Suzuki: "Formation of Liquid Crystalline Phase of Actin Filament Solutions and its Dependence on Filament length" Biophysical J.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Tadanao Ito: "Regulation of Osmotic Stress-induced Water Flow by the Cytoskeletal Structure Reconstituted by F-actin and Actin Binding Protein"

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary

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Published: 1988-04-01   Modified: 2016-04-21  

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