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Chemical Studies on the Substances Concerning Plants and Plant Pathogenic Fungi

Research Project

Project/Area Number 63303013
Research Category

Grant-in-Aid for Co-operative Research (A)

Allocation TypeSingle-year Grants
Research Field Chemical pharmacy
Research InstitutionNagasaki University

Principal Investigator

IRIE Hiroshi  Nagasaki Univ. Fac. of pharm. Sci. Prof., 薬学部, 教授 (00025686)

Co-Investigator(Kenkyū-buntansha) FUJITA Tetsuro  Kyoto Univ. Fac. of Pharm. Sci. Prof. and 12 contributors, 薬学部, 教授 (40027024)
MAYAMA Shigeyuki  Kobe Univ. Fac. of Agric Associate Prof., 農学部, 助教授 (00112251)
UENO Tamio  Kyoto Univ. Fac. of Agric. Associate Prof., 農学部, 助教授 (20026579)
TSUDA Yoshisuke  Kanazawa Univ. Fac. of Pharm. Sci., 薬学部, 教授 (40077508)
芳本 忠  長崎大学, 薬学部, 助教授 (60088870)
細見 彰  長崎大学, 薬学部, 教授 (00004440)
Project Period (FY) 1988 – 1990
Project Status Completed (Fiscal Year 1990)
Budget Amount *help
¥13,400,000 (Direct Cost: ¥13,400,000)
Fiscal Year 1990: ¥4,000,000 (Direct Cost: ¥4,000,000)
Fiscal Year 1989: ¥3,900,000 (Direct Cost: ¥3,900,000)
Fiscal Year 1988: ¥5,500,000 (Direct Cost: ¥5,500,000)
KeywordsPhytopathology / Host-specific Toxin / Self-inhibitor / Mushrooms / Specific enzyme / Nyctinastic movement / Crown rust fungi / Stereospecific Synthesis / 植物病原菌 / プロリン特異的酵素 / 植物の就眠運動 / エンバク冠さび病 / 植物病原体 / 宿主特異的的毒素 / 植物病源生産毒素 / 胞子自己発芽抑制因子 / 対昆虫摂食阻害物質 / 輪斑病菌生産植物毒素 / 植物病原菌生産ペプチド
Research Abstract

Each researcher of this research group has carried out the basic investigation on the structure elucidation and the synthetic work of the natural products. Some of them carried out the problems concerning the organic substances which have novel biological activities in plant pathology field. Thus, lrie's group has accomplished the synthesis of compounds toxic to Japanese white pear and revealed the structure-toxicity relationship of the toxins and also accompilshed the synthesis of a self-inhibitor to germination of plant pathogenic fungus. Tsuda's group has been carrying on the synthetic work on antifungus compound and vermicides. Mayama's group has been doing the precise investigation on phytoalexin which are produced in oat infected with fungus. And his group also has made their effort to confirm the presence of the elicitors which lay between plant and fungus cell, when the plants were infected with fungus. Uemura's group has been carrying out the isolation and structure elucidation work on marine natural products which have the unique biological activities. Yoshimoto's group has been carrying out the isolation work of enzymes from mushrooms, which have specific activity as endo-prolinase, and aiming at an ample supply of the enzymes using bio-technology. Ohfune's group are carrying out the synthetic work of peptides using the method developed by themselves. Other researchers of this group are carrying out synthetic work on the compounds available to biological tests and basic reserch work to develop the new synthetic methods. Each group has obtained the attractive results and found useful methods for the chemistry of natural products.

Report

(4 results)
  • 1990 Annual Research Report   Final Research Report Summary
  • 1989 Annual Research Report
  • 1988 Annual Research Report
  • Research Products

    (98 results)

All Other

All Publications (98 results)

  • [Publications] Hiroshi Irie: "Synthesis of Methoxyonyonychine and Use of |-^<|->Hー|and |-^<13-|>CーNuclear Magnetic Resonance Spectra for Structure Determination of Geometrical Isomers of Indanー1ーone Oxime Derivatives" Chem.Pharm.Bull.36. 3134-3137 (1988)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] Jun'ichi Katakawa: "Synthesis of Amaryllidanceae Alkaloids、(±)ーCherylline and (±)ーLatifine" Chem.Pharm.Bull.36. 3928-3931 (1988)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] Hioshi Irie: "Synthesis of an Alkaloid、(±)ー3ーDemethoxyeryterthratidinone" Heterocyles. 29. 1033-1035 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] Hiroshi Irie: "Lewis Acid Catalysed Preparation of some Carbamates and Sulphonylureas. Application to the Determination of Enantiomeric Purity of Chiral Alchols" J.Chem.Sco.,Perkin Trans.I. 1989. 1209-1210 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] Junko Koyama: "Synthesis of Alkaloids、Cleistopholine、Oxylopine、(Isoursuline)、and Ursuline" Heterocycles. 29. 1649-1654 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] Hiroshi Irie: "Sysnthesis of the Methyl Esters of AKーToxin II、a HostーSpecific Toxin to Japanese White Pear、and Its Congeners;StructureーToxicity Relatioship of the Toxin" Chem.Pharm.Bull.38. 1451-1461 (1990)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] Hiroshi Irie: "Use of Potassium Peroxodisulfate for Benzylic Oxidation and Oxidative Coupling of Benzoylacetates" SYNLETT. 1990. 421-424 (1990)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] Hiroshi Irie: "Synthesis of (±)ーHeritol、a Sesquiperepene Lactone belonging to the Aromatic Cadinane Group" Chem.Pharm.Bull.38. 1852-1856 (1990)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] Hiroshi Irie: "Zr(OーtーBu)|-_<4-|>、an Efficient and Convenient Basic Reagent in Organic Synthesis.Utilization in Cross and Intramoleclar Aldol Reactions" 55. 5306-5308 (1990)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] Hideo Nakamura: "Alkylated Levoglucosan in Organic Synthesis.A Formal Total Synthesis of Elaiophylin" Chem.Pharm.Bul.,. 38. 2435-2441 (1990)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] Masahiro Hirama: "New Entry to SynーbataーHydroxyーalpheーAmino Acid" Tetrahadron Letters. 29. 3125-3128 (1988)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] Kiyoshi Tomioka: "Design、Synthesis、and Antitumor Actitvity of Steganacin AzaーAnalogues" Tetrahedron Letters. 30. 2949-2952 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] Kiyoshi Tomioka: "Conjugat Addition Reaction of Organolithium to Naphthalenecarboxylate" Terahedron Letters. 31. 1739-1740 (1990)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] Akira Hosomi: "Synthesis and Consecutive Duble Alkylation Reaction of (2ーSiloxyallyl)silane the Synthetic Equibalent of Acotone α、α´ーDianion" J.Org.Chem.54. 3254-3256 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] Akira Hosomi: "2ーTrimethylsilylethyー1、3ーButadienen as a Synthetic Equivalent of Parent CrossーConjuhgated Hexatriene、3ーMethyleneー1、4ーPentadiene" Tetrahedron Letters. 31. 6201-6204 (1990)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] Yasumasa Hamada: "Stereoselective Total of AIー77ーB、a GastroーProtective Substance from Bucillus Pumilus AIー77" J.Am.Chem.Soc.111. 1524-1525 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] Toyohiko Aoyama: "Reaction of Trimethlsilydiazomethane with Olefins" Chem.Pharm.Bull.,. 37. 253-256 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] Naomi Saksi: "Stereoslective Synthesis of the Revised Structure of Galatanic Acid" Terahedron Letters. 31. 4151-4153 (1990)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] G.Spears: "Palladium Catalized ScN´ Reactions.Stereoselective Formation of Cyclic Carbamate from tertーButyldimethylーsilyl Carbamate" Tetrahedron Letters. 31. 1060-1061 (1990)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] Nobitaka Fujii: "Silver Trifluoromethanesulphonate as an SーDeprotecting Reagant for the Synthesis of Cystine Peptide" J.Chem.Soc.,Chem.Commun.,. 1989. 283-284 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] Toshiro Ibuka: "Determination of Absolute Configuration of the Alkyl Group at the αーAlkylー(E)ーβ、γーEnoates by Circulae Dichroism" Tetrahedron、Asymmetry. 1. 389-394 (1990)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] Akira Iida: "Fungal Metabolites IV.Synthesis of an Antibiotic Petide、Trichosporin BーV、from Trichoderma Polysporin" Chem.Pharm.Bull.,. 38. 2997-3003 (1990)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] Mugio Nishizawa: "αーSelective Thermal Glycosidation of Rhamnosyl and Mannosyl Chlorides" Tetrahedron Letters. 31. 2431-2434 (1990)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] Hideyuki Takenaka: "Chiral Induction in a Biominetic Olefin Cyclization" Tetrahedron Letters. 30. 2267-2268 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] Yoshikazu Shizuri: "Synthesis of (±)ーSilphinene using Electrochemical Method as a Key Step" Tetrahedron Letters. 30. 3797-3798 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] Shosuke Yamamura: "Diterpenes from Euphorbia Helioscopia" Phytochemistry. 28. 3421-3436 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] Fumiyuki Kikuchi: "Screening of Crude Drugs Used in Turkey for Nematocidal Activity on the Larve Toxocara canis" ShoyakugakuZasshi. 43. 353-359 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] Hideo Koshida: "Mineralocorticoid and Renal Receptor Binding Acivity of 21ーDeoxyaldosterone" Endocrnology. 126. 1410-1415 (1990)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] Shoji Yahara: "Structures of AntiーAce and ーRenin Peptides from LYCII Radicis Cortex" Tetrahedron Letters. 30. 6041-6042 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] Kazushi Shingu: "Two New Ergostane Derivatives from Tubocapsicum anomalum(Solanaceae)" Chem.Pharm.Bul´l.,. 38. 1107-109 (1990)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] Tadashi Yoshimoto: "An Aminopeptidase N from Escherichia coli HB101:Purification and Demonstration that the Enzyme possesses Arylamidase and Peptidase Activities" Agric.Biol.Chem.,. 52. 217-225 (1988)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] Tadashi Yoshimoto: "Purification and Enzymic Properties of an EndoーaーNーacetyl Galactosaminidase from Bacillus Laterosrus SSー16" J.Ferm.Biotech.,. 70. 348-350 (1990)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] Tamio Ueno(as a contributor) AttaーurーRahman/Editor: "Elsevier" Stdies in Natural Products Chemistry (Contributor),

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] Daisuke Uemua AttaーruーRahman/Editor: "Elsevier" Studies in Natural Products Chemistry Vol.5, 24 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] Yoshisuke Tsuda(as a contributor): "Elsevier" Studies in Natural Products Chemistry Vol.3, (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] H. Irie, M. Nishimura, M. Yoshida, and T. Ibuka: "Lewis Acid Catalyzed Preparation of some Carbamates and Sulphonylureas. Application to the Determination of Enantiomeric Purity of Chiral Alcohols" J. Chem. Soc.1989. 1209-1210 (1989)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] H. Irie, K. Matsumoto, T. Kitagawa, and Y. Zhang: "Synthesis of the Methyl Ester of AK-Toxin II, a Host-Specific Toxin to Japanese White Pear, and Its Congeners ; Structure-Toxicity Relationship of the Toxin" Chem. Pharm. Bull. 38. 1451-1461 (1990)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] H. Irie, J. Maruyama, Y. Zhang, I. Kouno, K. Shimamoto, and Y. Ohfune: "Use of Potassium Peroxodisulfate for Benzylic Oxidation and Oxidative Coupling of Benzoylacetates," SYNLETT. 421-423 (1990)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] H. Irie, R. Matsumoto, M. Nisimura, and Y. Zhang: "Synthesis of ((] SY. +-.[)-Heritol, a Sesquiterpen Lacton belonging ti the Aromatic Cadinane Group." Chem. Pharm. Bull. 38. 1852-1856 (1990)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] A. Iida, S. Yoshimatsu, M. Sanekata, and T. Fukita: "Fungal Metabolites. IV. Synthesis of an Antibiotic Peptide, Trichosporin B-V, from Trichoderma polysporum Chem. Pharm. Bull., 38, 2997-2003 (1990)." Chem. Pharm. Bull.38. 2997-2003 (1990)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] H. Sasai, Y. Kirio, and M. Shibasaki: "Zr(0-T-Bu)_4, an Efficient and Convenient Basic Reagenrt in Organic Synthesis. Utilization in Cross and Intramolecular Aldol Reaction" J. Org. Chem.55. 5306-5308 (1990)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] M. Hirama, H. Hioki, and S. Ito: "New Entry to syn-beta-Hydroxy-alpha-Amino Acid" Tetrahedron Letters. 29. 3125-3128 (1988)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] K. Tomioka, Y. Kubota, H. Kawasaki, and K. Koga: "Design, Synthesis, and Antitumor Activity of Steganacin Aza-Analogues" Tetrahedron Letters. 30. 2949-2952 (1989)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] D. Uemura, T. Chiba, Y. Hatashi, and J. Aiso: "Cytotoxic Alkaloids from the Marine Sponges" J. Nat. Prod.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] Y. Hamada, A. Kawai, Y. Kohno, O. Hara, and T. Shioiri: "Stereoselective Total Synthesis of AI-77-B, a Gastroprotective Substance from Bacillus pumilus AI-77" J. Am. Chem. Soc.111. 1524-1524

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] N. Fujii, A. Otaka, T. Watanabe, A. Okanachi, H. Tamamura, H. Yajima, Y. Inagaki, M. Nomizu, and K. Asano: "Silver Trifluoromethanesulphonate as an S-Deprotecting Reagent for the Synthesis of Cyctine Peptides" J. C. S. Chem. Commun. 1989. 283-284 (1989)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] H. Shigemori, N. Sakai, E. Miyoshi, Y. Shizuri, and S. Yamamura: "Bioactive Substances from Lespedeza cuneata L. G. Don and Their Biological Activities" Tetrahedron. 46. 383-394 (1990)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] N. Sakai and Y. Ohfune: "Stereoselective Synthesis of the Revised Structure of Galantinic acid" Tetraheron Letters. 31. 4151-4154 (1990)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] M. Nishizawa, Y. Kan, W. Shimomoto, and H. Yamada: "alpha-Selective Thermal Glycosidation of Rhamnosyl and Mannosyl Cholrides" Tetrahedron Letters. 31. 2431-2434

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] T. Yoshimoto, E. Takahashi, and D. Tsuru: "Purification and Enzymic Properties of an Endo-a-N-acetyl galactosaminidase from Bacillus lapterosporus SS-16" J. Ferm. Biotech.70. 348-350

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] Hiroshi Irie: "Synthesis of Methoxyonychine and Use of ^1Hーand ^<13>CーNuclear Magnetic Resonance Spectra for Structure Determination of Geometrical Isomers of Indanー1ーone Oxime Derivatives" Chem.Pharm.Bull.36. 3134-3137 (1988)

    • Related Report
      1990 Annual Research Report
  • [Publications] Jun'ichi Katakawa: "Synthesis of Amaryllidaceae Alkaloids,(±)ーCherylline and (±)ーLatifine" Chem.Pharm.Bull.36. 3928-3931 (1988)

    • Related Report
      1990 Annual Research Report
  • [Publications] Hiroshi Irie: "Synthesis of an Alkaloid,(±)ー3ーDemethoxyerythratidinone" Heterocyles. 29. 1033-1035 (1989)

    • Related Report
      1990 Annual Research Report
  • [Publications] Hiroshi Irie: "Lewis Acid Catalysed Preparation of some Carbamates and Sulphonylureas.Application to the Determination of Enantiomeric Purity of Chiral Alcohols" J.Chem.Soc.,Perkin Trans.I. 1989. 1209-1210 (1989)

    • Related Report
      1990 Annual Research Report
  • [Publications] Junko Koyama: "Synthesis of Alkaloids,Cleistopholine,Oxylopine,(Isoursuline),and Ursuline" Heterocycles. 29. 1649-1654 (1989)

    • Related Report
      1990 Annual Research Report
  • [Publications] Hiroshi Irie: "Synthesis of the Methyl Esters of AKーToxin II,a HostーSpecific Toxin to Japanese White Pear,and Its Congeners;StructureーToxicity Relatioship of the Toxin" Chem.Pharm.Bull.38. 1451-1461 (1990)

    • Related Report
      1990 Annual Research Report
  • [Publications] Hiroshi Irie: "Use of Potassium Peroxodisulfate for Benzylic Oxidation and Oxidative Coupling of Benzoylacetates" SYNLETT. 1990. 421-424 (1990)

    • Related Report
      1990 Annual Research Report
  • [Publications] Hiroshi Irie: "Synthesis of (±)ーHeritol,a Sesquiperpene Lactone belonging to the Aromatic Cadinane Group" Chem.Pharm.Bull.38. 1852-1856 (1990)

    • Related Report
      1990 Annual Research Report
  • [Publications] Hiroaki Sasai: "Zr(OーtーBu)_4,an Efficient and Convenient Basic Reagent in Organic Synthesis.Utilization in Cross and Intramolecular Aldol Reactions" 55. 5306-5308 (1990)

    • Related Report
      1990 Annual Research Report
  • [Publications] Hideo Nakamura: "Alkylated Levoglucosan in Organic Synthesis.A Formal Total Synthesis of Elaiophylin" Chem.Pharm.Bull.,. 38. 2435-2441 (1990)

    • Related Report
      1990 Annual Research Report
  • [Publications] Masahiro Hirama: "New Entry to SynーβーHydroxyーαーAmino Acid" Tetrahedron Letters. 29. 3125-3128 (1988)

    • Related Report
      1990 Annual Research Report
  • [Publications] Kiyoshi Tomioka: "Design,Synthesis,and Antitumor Activity of Steganacin AzaーAnalogues" Tetrahedron Letters. 30. 2949-2952 (1989)

    • Related Report
      1990 Annual Research Report
  • [Publications] Kiyoshi Tomioka: "Conjugate Addition Reaction of Organolithium to Naphthalenecarboxylate" Tetrahedron Letters. 31. 1739-1740 (1990)

    • Related Report
      1990 Annual Research Report
  • [Publications] Akira Hosomi: "Synthesis and Consecutive Double Alkylation Reaction of (2ーSiloxyallyl)silane as the Synthetic Equibalent of Acetone α,α'ーDianion" J.Org.Chem.54. 3254-3256 (1989)

    • Related Report
      1990 Annual Research Report
  • [Publications] Akira Hosomi: "2ーTrimethylsilylethylー1,3ーButadiene as a Synthetic Equivalent of Parent CrossーConjugated Hexatriene,3ーMethyleneー1,4ーPentadiene" Tetrahedron Letters. 31. 6201-6204 (1990)

    • Related Report
      1990 Annual Research Report
  • [Publications] Yasumasa Hamada: "Stereoselective Total Synthesis of AIー77ーB,a Gastroprotective Substance from Bucillus pumilus AIー77" J.Am.Chem.Soc.111. 1524-1525 (1989)

    • Related Report
      1990 Annual Research Report
  • [Publications] Toyohiko Aoyama: "Reaction of Trimethylsilyldiazomethane with Olefins" Chem.Pharm.Bull.,. 37. 253-256 (1989)

    • Related Report
      1990 Annual Research Report
  • [Publications] Naomi Sakai: "Stereoselective Synthesis of the Revised Structure of Galatanic Acid" Tetrahedron Letters. 31. 4151-4153 (1990)

    • Related Report
      1990 Annual Research Report
  • [Publications] G.Spears: "Palladium Catalized S_<cN'> Reactions.Stereoselective Formation of Cyclic Carbamate from tertーButyldimethylsilyl Carbamate" Tetrahedron Letters. 31. 1060-1061 (1990)

    • Related Report
      1990 Annual Research Report
  • [Publications] Nobitaka Fujii: "Silver Trifluoromethanesulphonate as an SーDeprotecting Reagent for the Synthesis of Cystine Peptide" J.Chem.Soc.,Chem.Commun.,. 1989. 283-284 (1989)

    • Related Report
      1990 Annual Research Report
  • [Publications] Toshiro Ibuka: "Determination of Absolute Configuration of the Alkyl Group at the αーAlkylー(E)ーβ,γーEnoates by Circulae Dichroism" Tetrahedron,Asymmetry. 1. 389-394 (1990)

    • Related Report
      1990 Annual Research Report
  • [Publications] Akira Iida: "Fungal Metabolites IV.Synthesis of an Antibiotic Peptide,Trichosporin BーV,from Trichoderma polysporin" Chem.Pharm.Bull.,. 38. 2997-3003 (1990)

    • Related Report
      1990 Annual Research Report
  • [Publications] Mugio Nishizawa: "αーSelective Thermal Glycosidation of Rhamnosyl and Mannosyl Chlorides" Tetrahedron Letters. 31. 2431-2434 (1990)

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      1990 Annual Research Report
  • [Publications] Hideyuki Takenaka: "Chiral Induction in a Biomimetic Olefin Cyclization" Tetrahedron Letters. 30. 2267-2268 (1989)

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      1990 Annual Research Report
  • [Publications] Yoshikazu Shizuri: "Synthesis of (±)ーSilphinene using Electrochemical Method as a Key Step" Tetrahedron Letters. 30. 3797-3798 (1989)

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      1990 Annual Research Report
  • [Publications] Shosuke Yamamura: "Diterpenes from Euphorbia Helioscopia" Phytochemistry. 28. 3421-3436 (1989)

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      1990 Annual Research Report
  • [Publications] Fumiyuki Kikuchi: "Screening of Crude Drugs Used in Turkey for Nematocidal Activity on the Larva of Toxocara canis" ShoyakugakuZasshi. 43. 353-359 (1989)

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      1990 Annual Research Report
  • [Publications] Hideo Koshida: "Mineralocorticoid and Renal Receptor Binding Acivity of 21ーDeoxyaldosterone" Endocrinology. 126. 1410-1415 (1990)

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  • [Publications] Shoji Yahara: "Structures of AntiーAce and ーRenin Peptides from LYCII Radicis Cortex" Tetrahedron Letters. 30. 6041-6042 (1989)

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  • [Publications] Kazushi Shingu: "Two New Ergostane Derivatives from Tubocapsicum anomalum (Solanaceae)" Chem.Pharm.Bull.,. 38. 1107-1109 (1990)

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      1990 Annual Research Report
  • [Publications] Tadashi Yoshimoto: "An Aminopeptidase N from Escherichia coli HB101:Purification and Demonstration that the Enzyme possesses Arylamidase and Peptidase Activities" Agric.Biol Chem.,. 52. 217-225 (1988)

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      1990 Annual Research Report
  • [Publications] Tadashi Yoshimoto: "Purification and Enzymic Properties of an EndoーaーNーacetyl Galactosaminidase from Bacillus Laterosrus SSー16" J.Ferm.Biotech.,. 70. 348-350 (1990)

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  • [Publications] Tamio Ueno(as a contributor) AttaーurーRahman/Editor: "Stdies in Natural Products Chemistry (Contributor)" Elsevier,

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  • [Publications] Daisuke Uemura AttaーurーRahman/Editor: "Studies in Natural Products Chemistry Vol.5" Elsevier, 24 (1989)

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  • [Publications] Yoshisuke Tsuda (as a contributor): "Studies in Natural Products Chemistry Vol.3" Elsevier, 49 (1989)

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  • [Publications] Hiroshi Irie: "Lewis Acid Catalysed Preparation of some Carbamates and Sulphonylureas.Application to the Determination of Enatiomeric Purity of Chiral Alcohols" J.Chem.Soc.,Perkin Trans.I. 1989. 1209-1210 (1989)

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  • [Publications] Hiroshi Irie: "Synthesis of an Alkaloid,(^+_-)-3-Demethoxyerythratidinone" Heterocycles. 29. 1033-1035 (1989)

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  • [Publications] Hiroshi Irie: "Synthesis of the Methyl Ester of AK-Toxin II.A Host-Specific Toxin to Japanese White Pear,and its Congeners:Structure-Toxicity Relationship of the Toxin" Chem.Pharm.Bull.38. (1990)

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  • [Publications] Tadashi Yoshimoto: "Studies on Prolyl Endopeptidase from Shakashimeji(Lyophyllum cinerasens):Purification and Enzymic Properties" J.Biochem. 104. 622-627 (1988)

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  • [Publications] Tetsurou Fujita: "Structure elucidation of trichosporin-B-Ia,IIa,IIId and V from Trichoderma polysporum" J.Antibiotics. 41. 814-818 (1988)

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  • [Publications] Yoshikazu Shizuri: "Short Step-synthesis and Biological Activity of Hauptmann's Perplanone A and its Stereoisomer" Tetrahedrom Letters. 29. 1971-1974 (1988)

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  • [Publications] Tamio Ueno: "Studies in Natural Products Chemistry Vol.?Edited by Atta-ur-Rahman" Elsevier(Amsterdam-Oxford-New York-Tokyo), (1990)

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  • [Publications] Hiroshi,IRIE.: Chem.Pharm.Bull.36. 3134-3137 (1988)

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  • [Publications] Masahiro HIRAMA.: Tetrahedron Letters. 29. 3125-3128 (1988)

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  • [Publications] Kiyoshi TOMIOKA: J.Am.Chem.Soc.110. 3597-3601 (1988)

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  • [Publications] Migio NISHIZAWA.: Tetrahedron Letters. 29. 4597-4598 (1988)

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      1988 Annual Research Report
  • [Publications] Nobutaka FUJII.: J.C.S.Chem.Commun.1988. 324-325 (1988)

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  • [Publications] Tetsuro FUJITA.: J.Antibiotics. 41. 814-818 (1988)

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      1988 Annual Research Report

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Published: 1988-04-01   Modified: 2016-04-21  

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