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Color Discrimination Processes in the Retina: Basic and Clinical Approaches

Research Project

Project/Area Number 63304031
Research Category

Grant-in-Aid for Co-operative Research (A)

Allocation TypeSingle-year Grants
Research Field Neurophysiology and muscle physiology
Research InstitutionKanazawa University

Principal Investigator

NEGISHI Koroku  Kanazawa Univ. Sch. Med., Prof., 医学部, 教授 (00019572)

Co-Investigator(Kenkyū-buntansha) MORITA Yukitomo  Hamamatsu Med. Univ., Prof., 教授 (80034164)
OHTSUKA Teruya  Nat. Inst. Pshyiol. Sci., Assoc. Prof., 生理研, 助教授 (10051814)
TOHYAMA Masaya  Osaka Univ. Sch. Med., Prof., 医学部, 教授 (40028593)
MIKI Naomasa  Osaka Univ. Sch. Med., Prof., 医学部, 教授 (40094445)
KANEKO Akimichi  Nat. Inst. Physiol. Sci., Prof., 生理研, 教授 (00051491)
河崎 一夫  金沢大学, 医学部, 教授 (20019920)
Project Period (FY) 1988 – 1989
Project Status Completed (Fiscal Year 1989)
Budget Amount *help
¥5,400,000 (Direct Cost: ¥5,400,000)
Fiscal Year 1989: ¥2,400,000 (Direct Cost: ¥2,400,000)
Fiscal Year 1988: ¥3,000,000 (Direct Cost: ¥3,000,000)
KeywordsVisual Science / Retina / Information Processing / Interdisciplinary Exchange / Color Vision / Cellular and Molecular Mechanisms / サイクリックヌクレオタイド代謝酵素 / 光電交換ディバイス
Research Abstract

In the following meetings, multidisciplinary scientists, particularly young active researchers were recruited, and they discussed on their results, future projects and interdisciplinary exchanges. The meetings contributed to further develop the general idea of co-operative research with neurobiological techniques in the future.
The 1st Meeting: Scientific conference on "Multidisciplinary Approaches to Visual Science", July 13-15, 1988 at National Institute for Physiological Sciences, Okazaki and Hamamatsu University School of Medicine. Presented papers, 19; special lectures, 2; participants, 60.
The 2nd Meeting: Scientific conference on "Cellular and Molecular Mechanisms of Retinal Function". Sept. 24 & 25, 1988 at Tokyo Women's Medical School. Presented papers, 24; Participants, 50.
The 3rd Meeting: Official conference on the future planning for application of Grants-in- Aid for Cooperative Research (B) and for Scientific Research on Priority Areas. Participants, 9.
The 4th Meeting: Scientific conference on "Interdisciplinary Understanding of Visual Information System", Aug. 4-6, 1989 at National Institute for Physiological Sciences, Okazaki. Presented papers, 23; special lectures, 3; participants, 76.
The 5th Meeting: Open Scientific Symposium'on "Cellular and Molecular Biology of Retinal Function", Nov. 10 & 11, 1989 at New Grand Inn, Kanazawa. Review papers, 5; special lectures 6; participants, 54. Here eleven speakers reviewed their-own works, analyzed the present international and interdisciplinary situation of retinal research, and pointed out what has been known and what has been left unknown. The grand supported the research members and their colleagues to attend the above meetings as well as to exchange new techniques between their laboratories. The aim of this project of cooperative research is believed to be fulfilled and appreciated.

Report

(3 results)
  • 1989 Annual Research Report   Final Research Report Summary
  • 1988 Annual Research Report
  • Research Products

    (37 results)

All Other

All Publications (37 results)

  • [Publications] Negishi,K.: "The dopamine system of the teleost fish retina" Prog.Retinal Res.9. 1-48 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Kaneko,A.: "Transient calcium current of retinal bipolar cells of the mouse" J.Physiol.410. 613-629 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Kuo,CーH.: "Translocation of MEKA protein in photoreceptor cells by light" Neurosci.Lett.103. 8-10 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Ohtsuka,T.: "Immunocytochemical studies of centrifugal fiber in the goldfish retina" Neurosci.Res.Suppl.10. S141-S150 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Kuo,CーH.: "Presence of retinaーspecific proteins in the lamprey pineal complex" Brain Res.442. 147-151 (1988)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Morita,Y.: "Response pattern and neuronal network of photosensory pineal organ" Arch Histol.Cytol.52(Suppl.). 469-475 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Negishi, K.: "Dopamine cells and rod bipolar cells contain protein kinase C-like immunoreactivity in some vertebrate retinas" Neurosci. Lett.93. 247-252 (1988)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Negishi, K.: "Identification of horizontal cells generating different spectral responses in the retina of a teleost fish (Eugerres plumieri)" J. Neurosci. Res., 20, 246-256, 1988.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Negishi, K.: "Morphological and functional correlates of horizontal cells in the retina of a teleost fish (Eugerres plumieri)" Biomed. Res., 9 (Suppl 2), 109-117, 1988.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Negishi, K.: "The dopamine system of the teleost fish retina" Prog. Retinal Res., 9, 1-48, 1989.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Negishi, K.: "Sequential course of uptake of intravitreal 5,7-DHT by carp retina cells" Brain Res., 508, 135-141, 1990.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Kaneko, A.: "Transient calcium current of retinal bipolar cells of the mouse" J. Physiol., 410, 613-629, 1989.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Suzuki, S.: "Effects of glycine and GABA on isolated bipolar cells of the mouse retina" J. Physiol., 421, 645-662, 1990.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Kuo, C-H.: "Isolation of a novel retina-specific clone (MEKA cDNA) encoding a photoreceptor soluble protein" Molec. Brain Res., 6, 1-10, 1988.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Kuo, C-H.: "Identification of a retina-specific MEKA protein as a 33K protein" Biochem. Biophys. Res. Comm., 162, 1063-1068, 1989.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Kuo, C-H.: "Translocation of MEKA protein in photoreceptor cells by light" Neurosci. Lett., 103, 8-10, 1989.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Kuo, C-H.: "Developmental changes of MEKA protein and opsin in normal and rd mice" Dev. Brain Res., 50, 139-141.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Iseki, S.: "A longitudinal study on the expression of opsin gene in the degenerating retina of C3H/He mice" Arch. Histol. Cytol., 52, 197-200, 1989.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Goto, K.: "An immunohistochemical study of pinealocytes of chicks and some lower vertebrates by means of visinin (retinal conespecific protein)-immunoreactivity" Arch. Histol. Cytol., 52, 451-458, 1989.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Hamano, K.: "Coexistence of enkephalin and somatostatin in the chicken retina" Brain Res., 489, 254-260, 1987.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Ohtsuka, T.: "Immunocytochemical studies of centrifugal fiber in the goldfish retina" Neurosci. Res. Suppl. 10, S141-S150, 1989.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Samejima, M.: "External sodium ions are required for the light response in pineal photoreceptors" Vision Res., 28, 251-258, 1988.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Kuo, C-H.: "Presence of retina-specific proteins in the lamprey" Brain Res., 442, 147-151, 1988.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Morita, Y.: "Response pattern and neuronal network of photosensory pineal organ" Arch. Histol. Cytol., 52 (Suppl.), 469-475, 1989.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Samejima, M.: "Photoreceptor cells and neural elements with long axonal processes in the pineal organ of lamprey, Lampetra japonica, identified by use of the HRP method" Cell Tiss. Res., 258, 219-224, 1989.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Negishi,K.,Salas,R.,Parthe,V.& Drujan,B.D.: "Identification of horizontal cells generating different spectral responses in the retina of a teleost fish(Eugerres Plumieri)" J.Neurosci.Res.20. 246-256 (1988)

    • Related Report
      1989 Annual Research Report
  • [Publications] 金子章道: "色覚に関する情報処理:三原色と反対色" 蛋白質・核酸・酵素. 34. 652-662 (1989)

    • Related Report
      1989 Annual Research Report
  • [Publications] Kaneko,A.,Pinto,L.H.& Tachibana,M.: "Transient calcium current of retinal bipolar cells of the mouse" J.Physiol.410. 613-629 (1989)

    • Related Report
      1989 Annual Research Report
  • [Publications] Kuo,C-H.,Akiyama,M.& Miki,N.: "Isolation of a novel retina-specific clone(MEKA cDNA)encoding a photoreceptor soluble protein" Molec.Brain Res.6. 1-10 (1988)

    • Related Report
      1989 Annual Research Report
  • [Publications] Hamano,K.,Manabe,R.& Tohyama,M.: "Coexistence of enkephalin and somatostatin in the chicken retina" Brain Res.489. 254-260 (1987)

    • Related Report
      1989 Annual Research Report
  • [Publications] 大塚輝彌: "色情報抽出の網膜神経回路" 動物生理. 6. 49-57 (1989)

    • Related Report
      1989 Annual Research Report
  • [Publications] Negishi, K.,et al.: J. Neurosci. Res.20. 246-256 (1988)

    • Related Report
      1988 Annual Research Report
  • [Publications] Tachibana, M.;Kaneko, A.: proc. Natl. Acad. Sci. USA. 85. 5315-5319 (1988)

    • Related Report
      1988 Annual Research Report
  • [Publications] Miki, N.,et al.: Molec. Brain Res.(1989)

    • Related Report
      1988 Annual Research Report
  • [Publications] Tohyama, M.,at al.: Brain Res.(1989)

    • Related Report
      1988 Annual Research Report
  • [Publications] Ohtsuka, T.,et al.: Neurosci. Res.Suppl. 9. (1989)

    • Related Report
      1988 Annual Research Report
  • [Publications] 河崎一夫 他: 眼紀. 39. 1501-1511 (1989)

    • Related Report
      1988 Annual Research Report

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Published: 1988-04-01   Modified: 2016-04-21  

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