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Study for mechanism of proliferation in viral lymphadenitis - Characteristics in Japanese -

Research Project

Project/Area Number 63304035
Research Category

Grant-in-Aid for Co-operative Research (A)

Allocation TypeSingle-year Grants
Research Field Human pathology
Research InstitutionFukushima Medical College

Principal Investigator

WAKASA Haruki  Fukushima Medical College, Department of Pathology, Professor, 医学部, 教授 (30004568)

Co-Investigator(Kenkyū-buntansha) KIKUCHI Masahiro  Fukuoka University, School of Medicine, Department of Pathology, Professor, 医学部, 教授 (80078774)
MIKATA Atsuo  Chiba University, School of Medicine, Department of Pathology, Professor, 医学部, 教授 (40051289)
MORI Shigeo  Tokyo University, Institute of Medical Science, Department of Pathology, Profess, 医科学研究所, 教授 (30010424)
SHIRAKAWA Shigeru  Mie University, School of Medicine, Department of Internal Medicine, Professor, 医学部, 教授 (20026850)
MINAMISHIMA Youichi  Miyazaki Medical College, Department of Bacteriology, Professor, 医学部, 教授 (80041284)
花岡 正男  京都大学。ウィルス研究所, 教授 (30027304)
Project Period (FY) 1988 – 1989
Project Status Completed (Fiscal Year 1989)
Budget Amount *help
¥13,300,000 (Direct Cost: ¥13,300,000)
Fiscal Year 1989: ¥6,500,000 (Direct Cost: ¥6,500,000)
Fiscal Year 1988: ¥6,800,000 (Direct Cost: ¥6,800,000)
KeywordsViral lymphadenopathy / Necrotizing lymphadenitis / Kimura's disease / Paracortical hyperplasia / AIDS / ウィルス性リンパ節炎、壊死性リンパ節炎 / 副皮質増生性リンパ節炎
Research Abstract

In order to elucidate the mechanism of system of proliferation in lymphoid tissue, the research group mainly studied the reactive lymphadenopathy such as necrotizing lymphadenitis, Kimura's disease and AIDS lymphadenopathy.
1. Reactive disorders: In necrotizing lymphadenitis, hematological and histological investigation revealed that this disease may have close relationship between virus because of showing transient raising of serum 2'-5' oligoadenylate acid synthetic enzyme and human herpesvirus-6 antibody, appearing of cytopathic effect of lymphocytes and persistent of c-fos gene product. IgE Fc receptor positive cells coincided with lymphoid tissue in Kimura's disease. In addition, the development of this lesion in lymph nodes is similar to those in soft tissue. In AIDS, follicular dendritic cells are destructed even at the early stage of the AIDS but T zone histiocytes and sinus histiocytes are almost intact at late stage. AIDS are reliable to combined with extranodal malignant lymphoma and Epstein-Barr virus infection.
2. Making monoclonal antibody, which is specific to interdigitating cells such as ID 1, 2, 3, and 4, the analysis of E-B virus gene by in situ hybridization and characterization of reticular lymphocytes lesion (RL-focus) were studied.

Report

(3 results)
  • 1989 Annual Research Report   Final Research Report Summary
  • 1988 Annual Research Report

Research Products

(129 results)

All Other

All Publications (129 results)

  • [Publications] 浅野重之、他: "特集:生体における感染防御と破綻-リンパ節における感染防御" 化学療法の領域. 4. 1919-1925 (1988)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] 浅野重之、他: "特集:生体における感染防御と破綻-リンパ節における破綻と感染" 化学療法の領域. 4. 1926-1933 (1988)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] 若狭治毅、他: "壊死性リンパ節炎" 日本臨床. 47. 122-128 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] 浅野重之、他: "壊死性リンパ節炎" 日本臨床. 増刊号. (1990)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Eizuru,Y.et al.: "Human herpesvirus 6 in lymph nodes" Lancet. 40 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] 南嶋洋一: "Human herpesvirus 6およびその感染症" 病理と臨床. 8. (1990)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] 堀江弘、他: "単純ヘルペウイルスによるリンパ節炎の1症例" 病理と臨床. 6. (1988)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] 下条直樹、他: "慢性EBウイルス感染症と考えられ、最終的に悪性リンパ腫で死亡した男の男児症例" 臨床血液. 29. (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Ohkawa,H.,et al.: "Nobel functions and cellular interaciton of human lymphoid stromal cells with lymphoid cell lines in vitro" Exp.Hematol.17. 30-33 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] 三方淳男、他: "本邦悪性リンパ腫の現状と問題点" 病理と臨床. 7. 804-808 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Imai,Y.,et al.: "Endogenous sex hormone and esterogen binding activity in thyroid cancer" Histol.Histopath.4. 39-45 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Imai,Y.,et al.: "A morphological and immunohistochemical study of lymphoic germinal centers in synovial and lymph node tissues from rheumatoid arthritis patients with special reference to complement components and their receptors" Acta Pathol.Jpn.39. 127-134 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Imai,Y.,et al.: "Malignant fibrous histiocytoma:similarities to the "fibro-histiocytoid cells"in chronic inflammation" Virchows Archiv.A Pathol.Anat.414. 285-298 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Mori,N.,et al.: "DRC antigen expression in B cell lymphomas" Am.J.Clin.Pathol.90. (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Mori,N.,et al.: "Demonstration of intracytoplasmic immunoglobulin in non-T-acute lymphocytic leulemia cases of children with immunoelectron microscopic examination" Cancer. 61. (1988)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Oka,K.,et al.: "Childhood Ki-1 lymphoma:A report of two cases" Arch Pathol.Lab.Med.113. (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Mori,N.,et al.: "T-cell receptor(TCR)expression in the T cell malignancies" Am.J.Clin.Pathol.(1990)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] 小島勝、他: "Monocytoid B Lymphocyteの増殖巣を伴う膿瘍形成性肉芽腫性リンパ節炎について-特に猫ひっかき病との関係" 日網会誌. 29. 97-103 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Sugawara,I.et al.: "Further characterization of surfated homopolydsaccharides as anti-HIV agents" Experientia. 45. 996-998 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Mori,S.,et al.: "Involution of lymph node histiocytes in AIDS" Acta Pathol.Jpn.39. 496-502 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Kanaitsuka,T.,et a: "Persistent and enhanced expression of c-fos gene product in various kinds of human hematopoietic cell lines" Acta Pathol.Jpn.38. 1523-1536 (1988)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Miyatake,S.,et al.: "Specific cytotoxic activity of T lymphocyte clones derived from a gliosarcoma patient" J.Neurosurgery. 69. 751-759 (1988)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Kanaitsuka,T.,et a: "Detection of fos oncogene products by monoclonal antibody FO-120 in lymphoproliferative disorders" Leukemia Research. Dec.(1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Iwahashi,M.,et al.: "C-fos gene products in ATL patients and HTLV-1 healthy carriers" Acta Homatol.Jap.(1990)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Miwa,H.,et al.: "Immunogenotypes of lymphoid malignancies;the rearrangement of T cell receptor β chain gene can occur before the γ chain gene" Jpn J Cancer Res. 79. 484-490 (1988)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Nosaka,T.,et al.: "Crosslineage gene rearrangements in human leukmic B-precursor cells occur frequently with V-DJ rearrangements of IgH genes" Blood. 74. 361-368 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] 白川茂、他: "急性リンパ性白血病(ALL)造血器腫瘍の治療,最近の進歩" 日内会誌. 78. 769-773 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] 三輪啓志、他: "悪性リンパ腫診断における分子遺伝子学的手法の有用性と限界" 日網会誌. 29. 127-135 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] 森茂郎、他: "エイズと悪性リンパ腫" エイズジャ-ナル. 2. 119-124 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] 森茂郎、他: "AIDSの病理" 病理と臨床. 7. 1501-1508 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Nakamura,S..,et al.: "Interdigitating cell sarcoma(ICS):evidence of interdigitating cell origin,immunocytochemical studies with monoclonal anti-ICS antibodies" Virchows Archiv.A Pathol.Anat.415. 447-457 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Kojima,M.,et al.: "Reactive proliferative lesions in lymph nodes from rheumatoid arthritis patients.A clinicopathological and immunohistological study" Acta Pathol.Jpn.(1990)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] 白川茂、他: "リンパ球系悪性腫瘍の遺伝型.白血病.悪性リンパ腫" 南江堂, 276-284 (1988)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Namba,Y.et al.: "A novel antigen expressed in the HTLV-1-infected cells detected with a monoclonal antibody Lymphoid Malignancy" Field & Wood Publishers, 25-32 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Ueda,R.,et al.: "Proliferating cell population in angioimmunoblastic lymphadeno-pathy with dysproteinemia Lymphoid Malignancy in press" Field & Wood Publishers, (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Imai,Y.,st al.: "Follicular dendritic cells in lymphoid malignancies - morphology,distribution,and function Lymphoid Malignancy" Field & Wood Publishers, 229-242 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Kikuchi,M.,et al.: "Histiocytic nicrotizing lymphadenitis:Clinicopathologic,immunologic,and HLA typing study Lymphoid Malignancy in press" Field & Wood Publishers, (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] 難波雄二郎: "増殖T細胞の細胞内代謝,Immunology I" 同文書院, 117-125 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Mikata,A.,et al.: "Childhood lymphoma in Japan,immunohistologic and clinico-pathoologic review.Lymphoid Neoplasms" Field & Wood Publishers, (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Asano, S., et al.: "Defence against infection and destruction of man -Defence in lymph node" Antibiotics and Chemotherapy. 4. 1919-1925 (1988)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Asano, S., et al.: "Defence against infection and destruction of man -Destruction and infection in lymph node" Antibiotics and Chemotherapy 4: 1926-1933, 1988.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Wakasa, H., et al.: "Necrotizing lymphadenitis" Jap. J. Clin. Med. 47: 122-127, 1989.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Asano, S., et al.: "Necrotizing lymphadenitis" Jap. J. Clin. Med. in press, 1990.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Eizuru, Y., et al.: "Human herpesvirus 6 in lymph nodes" Lancet i: 40, 1989.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Minamishima, Y.: "Human herpesvirus 6 and its infections" Pathology & Clinical 8: in press, 1990.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Miwa, H., et al.: "Immunogenotypes of lymphoid malignancies; the rearrangement of T cell receptor beta chain gene can occur before the gamma chain gene rearrangement" Jpn. J. Cancer Res. 79: 484-490, 1988.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Nosaka, T., et al.: "Cross-lineage gene rearrangements in human leukemic B-precursor cells occur frequently with V-DJ rearrangements of IgH genes" Blood 74: 361-368, 1989.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Shirakawa, S., et al.: "Acute lymphocytic leukemia" Jap. J. Int. Med. 78: 769-773, 1989.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Miwa, K., et al.: "The usefulness and limitation of molecular genetic analysis in diagnosing malignant lymphoma" Jap. J. RES 29: 127-135, 1989.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Kanaitsuka, T., et al.: "Persistent and enhanced expression of c-fos gene product in various kinds human hematopoietic cell lines" Acta Pathol. Jpn. 38: 1523-1536, 1988.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Miyatake, S., et al.: "Specific cytotoxic activity of T lymphocyte clones derived from a gliosarcoma patient" J. Neurosurgery 69: 751-759, 1988.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Kanaitsuka, T., et al.: "Detection of fos oncogene products by monoclonal antibody FO-120 in lymphoproliferative disorders" Leukemia Research Dec. 1989.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Iwahashi, M., et al.: "C-fos gene products in ATL patients and HTLV-1 healthy carriers" Acta Hematol. Jap. in press, 1990.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Horie, H., et al.: "A case of localized herpes simplex lymphadenitis" Pathology & Clinical 6, 1988.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Shimojo, N., et al.: "Chronic EB virus infection terminated in malignant lymphoma: a case report" Clin. Hematol. 29, 1988.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Ohkawa, H., et al.: "Nobel functions and cellular interaction of human lymphoid stromal cells with lymphoid cell lines in vitro" Exp. Hematol. 17: 30-33, 1989.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Mikata, A.: "Trends and problems of malignant lymphoma in Japanese" Pathology & Clinical 7: 804-808, 1989.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Imai, Y. et al.: "Endogenous sex hormone and estrogen binding activity in thyroid cancer" Histol. Histopath. 4: 39-45, 1989.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Imai, Y., et al.: "A morphological and immunohistochemical study of lymphoid germinal centers in synovial and lymph node tissues from rheumatoid arthritis patients with special reference to complement components and their receptors" Acta Pathol. Jpn. 39: 127-134, 1989.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Imai, Y., et al.: "Malignant fibrous histiocytoma: similarities to the "fibrohistiocytoid cells" in chronic inflammation" Virchows Archiv. A Pathol. Anat. 414: 285-298, 1989.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Kikuchi, M., et al.: "Histiocytic necrotizing lymphadenitis: Clinicopathologic, immunologic, and HLA typing study" Lymphoid Malignancy Field & Wood Publishers in press.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Ueda, R., et al.: "Proliferating cell population in angioimmunoblastic lymphadenopathy with dysproteinemia" Lymphoid Malignancy Field & Wood Publishers in press.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Mori, N., et al.: "DRC antigen expression in B cell lymphomas" Am. J. Clin. Pathol. 90, 1988.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Mori, N., et al.: "Demonstration of intracytoplasmic immunoglobulin in non-T-acute lymphocytic examination" Cancer 61, 1988.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Oka, K., et al.: "Childhood Ki-1 lymphoma: A report of two cases" Arch Pathol. Lab. Med. 133, 1989.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Mori, N., et al.: "T-cell receptor (TCR) expression in the T cell malignancies" Am. J. Clin. Pathol.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Kojima, M., et al.: "Abscess forming granulomatous lymphadenitis with foci of monocytoid B lymphocyte proliferation" Jap. J. RES 29: 97-103, 1989.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Nakamura, S., et al.: "Interdigitating cell sarcoma (ICS): evidence of interdigitating cell origin, immunocytochemical studies with monoclonal anti-ICS antibodies" Virchow Archiv A. Pathol. Anat. 415: 447-457, 1989.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Kojima, M., et al.: "Reactive proliferative lesions in lymph nodes from rheumatoid arthritis patients. A clinicopathological and immunohistological study" Acta Pathol. Jpn. 1990.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] 若狭治毅: "壊死リンパ節炎" 日本臨床. 47. 122-127 (1989)

    • Related Report
      1989 Annual Research Report
  • [Publications] 浅野重之: "壊死性リンパ節炎" 日本臨床. 増刊号. (1990)

    • Related Report
      1989 Annual Research Report
  • [Publications] Eizuru,Y.: "Human herpesviruus 6 in lymph nodes" Lancet. i. 40 (1988)

    • Related Report
      1989 Annual Research Report
  • [Publications] 南嶋洋一: "Human herpesvirus 6およびその感染症" 病理と臨床. 8. (1990)

    • Related Report
      1989 Annual Research Report
  • [Publications] 白川茂: "リンパ系悪性腫瘍" 診断と治療. 77. 547-553 (1989)

    • Related Report
      1989 Annual Research Report
  • [Publications] 大野敏之: "悪性リンパ腫の表現型と遺伝子型" 臨床科学. 25. 1317-1377 (1989)

    • Related Report
      1989 Annual Research Report
  • [Publications] Sugawara,I.: "Further characterization of surfated homopolydsaccharides as anti-HIV agents" Experientia. 45. 996-998 (1989)

    • Related Report
      1989 Annual Research Report
  • [Publications] Mori,S.: "Involution of lymph node histiocytes in AIDS" Acta Pathol.Jpn.39. 496-502 (1989)

    • Related Report
      1989 Annual Research Report
  • [Publications] Kanaitsuka,: "Detection of fos oncogene products by monoclonal antibody F0-120 in lymphoproliferative disorders" Leukemia Research. (1989)

    • Related Report
      1989 Annual Research Report
  • [Publications] Iwahashi,M.: "C-fos gene products in ATL patients and HTLV-1 healthy carriers" Acta Hematol.Jap.(1990)

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  • [Publications] 三方淳男: "本邦悪性リンパ腫の現状と問題点" 病理と臨床. 7. 804-808 (1989)

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  • [Publications] Imai,Y.: "Endogenous sex hormone and estrogen binding activity in thyroid cancer" Histol.Histopath.4. 39-45 (1989)

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  • [Publications] Oka,K.: "Childhood Ki-l lymphoma:A report of two cases" Arch.Pathol.Lab.Med.113. (1989)

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  • [Publications] Mori,N.: "T-cell receptor(TCR)expression in the T cell malignancies" Am.J.Clin.Pathol.

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  • [Publications] Nakamura,S.: "Interdigitating cell sarcoma(ICS):evidence of interdigitating origin,immunocytochemical studies with monocldonal anti-ICS a" Virchow Archiv A Pathol Anat. 415. 447-457 (1989)

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  • [Publications] Kojima,M.: "Reactive proliferative lesions in lymph nodes from rheumatoid arthritis patients.A clinicopathological and immunohistologic" Acta Pathol.Jpn.(1990)

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  • [Publications] Imai,Y.: "Follicular dendritic cells in lymphoid malignancies-morphology,distribution,and function Lymphoid Malignancy" Hanaoka,M., 229-242 (1990)

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  • [Publications] Kikuchi,M.: "Histiocytic necrotizing lymphadenitis:Clinicopathologic,immunologic,and HLA typing study Lymphoid Malignancy" Field & Wood, (1990)

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  • [Publications] Ueda,R.: "Proliferating cell population in angioimmunoblastic lymphadenopath with dysproteinemia Lymphoid Malignancy" Field & Wood, (1990)

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  • [Publications] 若狭治毅、村松尚夫: 癌治療、今日と明日. 10. 21-25 (1988)

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Published: 1988-03-31   Modified: 2016-04-21  

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