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"The Cell Destruction with Super Pulse Laser Under the Different Bands of Wave Length. "

Research Project

Project/Area Number 63440045
Research Category

Grant-in-Aid for General Scientific Research (A)

Allocation TypeSingle-year Grants
Research Field General surgery
Research InstitutionUniversity of Tokyo

Principal Investigator

ABE Yusuke (1989-1990)  Faculty of Medicine, University of Tokyo, Instructor, 医学部・医学科, 助手 (90193010)

渥美 和彦 (1988)  東京大学, 医学部, 教授 (70009877)

Co-Investigator(Kenkyū-buntansha) FUJIMASA Iwao  Reserch Center for Advanced Science and Technology, University of Tokyo, Profess, 先端科学技術研究センター, 教授 (30010028)
MABUCHI Kunihiko  Reserch Center for Advanced Science and Technology, University of Tokyo, Assoc., 先端科学技術研究センター, 助教授 (50192349)
YONEZAWA Takumi  Faculty of Medicine, University of Tokyo, Instructor, 医学部, 助手 (50221677)
IMACHI Kou  Faculty of Medicine, University of Tokyo, Assoc. Prof., 医学部, 助教授 (10010076)
阿部 裕輔  東京大学, 医学部, 助手 (90193010)
Project Period (FY) 1988 – 1990
Project Status Completed (Fiscal Year 1990)
Budget Amount *help
¥28,900,000 (Direct Cost: ¥28,900,000)
Fiscal Year 1990: ¥2,500,000 (Direct Cost: ¥2,500,000)
Fiscal Year 1989: ¥11,400,000 (Direct Cost: ¥11,400,000)
Fiscal Year 1988: ¥15,000,000 (Direct Cost: ¥15,000,000)
KeywordsSuper pulse laser / Cell destruction / Tissue reaction / Endscope / Laser Surgery / Spinal Surgery / Arthroscopy / Heart Surgery / 脊髄手術 / エキシマレ-ザ- / パルスYAGレ-ザ- / 生体作用 / 選択的破壊 / ミトコンドリア / スーパーパルスレーザー / パルスYAGレーザー / エキシマレーザ
Research Abstract

The objectives of this study are to clarify the mechanism of cell destruction with super pulse laser, and perform the basic study for the medical application of super pulse laser.
The following results were obtained.
1. Cell destruction by super pulse laser.
The change of the muscle cell after the irradiation of super pulse laser with low energy were (1) nothing in infra-red band, (2) mitochondrial expansion in green band and (3) mitochondrial vacuolation in ultra-violet band by the electro-micrographical observation.
2. Tissue reaction by super pulse laser.
The tissue reaction in liver and spleen after the irradiation of super pulse laser with high energy were thought to be caused by (1) heat generation in infra-red band and (2) direct photon effect or shock wave effect in green and ultra-violet bands.
3. Medical application of super pulse laser.
(1) Spinal endoscopic laser surgery ; The radial nerves could be cut by super pulse laser under the spinal endoscopic visual field.
(2) Arthroscopic laser surgery ; The joint tissue reaction was observed to be effective for cutting, coagulation and vaporization with super pulse laser.
(3) Endoscopic Laser heart surgery ; The reaction of human mitral valve with laser were investigated to select the laser and irradiating condition.

Report

(4 results)
  • 1990 Annual Research Report   Final Research Report Summary
  • 1989 Annual Research Report
  • 1988 Annual Research Report
  • Research Products

    (34 results)

All Other

All Publications (34 results)

  • [Publications] 渥美 和彦: "レ-ザ医学の将来" 日本レ-ザ医学会誌. 9(3). 1-5 (1988)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] 阿部 裕輔: "波長帯域別ス-パ-パルスレ-ザ-の細胞破壊作用に関する基礎作用に関する基礎的研究" 日本レ-ザ医学会誌. 10(3). 501-504 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] 河野 明正: "波長帯域別ス-パ-パルスレ-ザ-の組織作用に関する基礎的研究" 日本レ-ザ-医学会誌. 10(3). 497-500 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] 阿部 裕輔: "エキシマレ-ザによる血管形成" 日本レ-ザ-医学会誌. 10(1). 31-36 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] 鎮西 恒雄: "高出力半導体レ-ザの内視鏡的応用に関する基礎的研究" 日本レ-ザ医学会誌. 10(3). 269-272 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] 鈴川 正之: "背髄の経皮的内視鏡下手術に関する基礎的研究" 日本レ-ザ医学会誌. 10(3). 171-174 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] M・SuzuKawa: "Percu taneous fiber opimal laser end scopy" Journal of climical Laser Medicine and Surgery. 8(6). 27-30 (1990)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] 河野 明正: "ス-パ-パルス-レ-ザ-の組織切離における熱作用に関する研究" 日本レ-ザ-医学会誌. 11(3). (1991)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] 米澤 卓実: "親子内視鏡による関節内レ-ザ-手術装置" 日本レ-ザ-医学会誌. 11(3). (1991)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] 今西 薫: "レ-ザ-による経皮的僧帽弁形成術のための基礎的検討" 医工学治療. 論文集. (1991)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] 今西 薫: "レ-ザによる経皮的僧帽弁形成術のための基礎的検討:狭窄弁におけるレ-ザ-作用に関する組織学的検討" 第21回日本心臓血管外科学会論文集. 特別号. (1991)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] K. Atsume: "Future of laser medicine and surgery," J. of Japan Soc. for Laser Med.9(3). 1-5 (1988)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] Y. Abe, et al: "Reaction of super pulse laser in cell destruction under different band of wave length" J. of Japan Soc. for Laser Med.10(3). 501-504 (1989)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] A. Kouno et al: "Tissue effects of super pulse YAG laser with different wave length" J. of Japan Soc. for Laser Med.10(3). 497-500 (1989)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] Y. Abe: "Laser angioplasty with excimer laser" J. of Japan Soc. for Laser Med.10(1). 31-36 (1989)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] T. Chinzei et al: "Endoscopic application of high power semiconductor laser" J. of Japan Soc. for Laser Med.10(3). 269-272 (1989)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] M. Suzukawa et al: "A basic study on percutaneous endoscopic spinal laser surgery" J. of Japan Soc. for Laser Med.10(3). 171-174 (1989)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] M. Suzukawa et al: "Percutaneous fiber optic spinal laser endoscopy" J. of Clinical Laser Med. and Surg.8(6). 27-30 (1990)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] A. Kouno et al: "Tissue degeneration of rabbit liver by irradiation of super pulse laser with different wave length" J. of Japan Soc. for Laser Med.11(3). (1991)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] T. ono et al: "Double monitoring arthroscope with laser" J. of Japan Soc. for Laser Med.11(3). (1991)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] M.Suzukawa: "Percutaneous fiber optic spinal laser endoscopy" Journal of Clinical Laser Medicine and Surgery. 8(6). 27-30 (1990)

    • Related Report
      1990 Annual Research Report
  • [Publications] 河野 明正: "ス-パ-パルスレ-ザ-の組織切離における熱作用に関する研究" 日本レ-ザ-医学会誌. 11(3). (1991)

    • Related Report
      1990 Annual Research Report
  • [Publications] 鈴川 正之: "レ-ザ-内視鏡を用いた経皮的選択的神経根切断術" 日本レ-ザ-医学会誌. 11(3). (1991)

    • Related Report
      1990 Annual Research Report
  • [Publications] 小野 俊哉: "親子内視鏡による関節内レ-ザ-手術装置" 日本レ-ザ-医学会誌. 11(3). (1991)

    • Related Report
      1990 Annual Research Report
  • [Publications] 今西 薫: "レ-ザ-による経皮的僧帽弁形成術のための基礎的検討:狭窄弁におけるレ-ザ-の作用に関する組織学的検討" 第21回日本心臓血管外科学会論文集. 特別号. (1991)

    • Related Report
      1990 Annual Research Report
  • [Publications] 今西 薫: "レ-ザ-による経皮的僧帽弁形成術のための基礎的検討" 医工学治療. 論文集. (1991)

    • Related Report
      1990 Annual Research Report
  • [Publications] 阿部裕輔: "波長帯域別ス-パ-パルスレ-ザ-の細胞破壊作用に関する基礎的研究" 日本レ-ザ-医学会誌. 10(3). 501-504 (1990)

    • Related Report
      1989 Annual Research Report
  • [Publications] 河野明正: "波長帯域別ス-パ-パルスレ-ザ-の組織作用に関する基礎的研究" 日本レ-ザ-医学会誌. 10(3). 497-500 (1990)

    • Related Report
      1989 Annual Research Report
  • [Publications] T.Yonezawa: "Basic Research for The Application of Super Pulse YAG Laser to Arthroscopic Surgery" Laser 90,International YAG Symposium Abstract Book. 79 (1990)

    • Related Report
      1989 Annual Research Report
  • [Publications] 河野明正: "ス-パ-パルスレ-ザによる生体組織の破壊作用" 医用電子と生体工学. 28(特別号). (1990)

    • Related Report
      1989 Annual Research Report
  • [Publications] 小野俊哉: "ス-パ-パルスレ-ザ-の細胞内小器官に及ぼす作用に関する研究" 医用電子と生体工学. 28(特別号). (1990)

    • Related Report
      1989 Annual Research Report
  • [Publications] 米沢卓実: "ス-パ-パルスレ-ザ-の整形外科応用に関する基礎的研究" 医用電子と生体工学. 28(特別号). (1990)

    • Related Report
      1989 Annual Research Report
  • [Publications] 米沢卓実: 医用電子と生体工学. 26. 513 (1988)

    • Related Report
      1988 Annual Research Report
  • [Publications] 渥美和彦: 日本レーザー医学会誌. 9. 1-12 (1988)

    • Related Report
      1988 Annual Research Report

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Published: 1988-04-01   Modified: 2016-04-21  

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