| Project/Area Number |
63460089
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| Research Category |
Grant-in-Aid for General Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Fluid engineering
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| Research Institution | University of Tokyo |
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Principal Investigator |
TANIDA Yoshimichi Univ. of Tokyo, RCAST, Professor, 先端科学技術研究センター, 教授 (50013628)
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| Co-Investigator(Kenkyū-buntansha) |
SHIMIZU Masashi Tokyo Inst. of Tech., Engg. Faculty, Assoc. Professor, 工学部, 助教授 (10013731)
NAGASHIMA Toshio Univ. of Tokyo, Engg.Faculty, Professor, 工学部, 教授 (70114593)
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| Project Period (FY) |
1988 – 1989
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| Project Status |
Completed (Fiscal Year 1989)
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| Budget Amount *help |
¥7,200,000 (Direct Cost: ¥7,200,000)
Fiscal Year 1989: ¥2,100,000 (Direct Cost: ¥2,100,000)
Fiscal Year 1988: ¥5,100,000 (Direct Cost: ¥5,100,000)
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| Keywords | Arteriocleorisis / Blood Flow / Blood Vessel / PSD / Pulsating Flow |
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| Research Abstract |
The mechanism of the generations of arterioscleorisis and PSD in artery was studied from the fluiddynamic standpoint by experiment and by numerical analysis.
Experiment: Two experimental test rigs were originally designed and manufactured for the studies on simulation model and bloodvessel model. On the simulation model, measurements were carried out in the steady and pulsating flows through a pipe with spindle-shaped contraction. The pressure fluctuation in separated recirculating region and the movement of the flow reattachment point were studied remarking the wall failure of the blood vessel. On the blood-vessel model, the shearing stress and the pressure on the vessel wall were measured in the flow through the rigid and elatic pipes with contraction. It was shown that the occurrence of a reversed flow leads to marked change in the shearing stress but not in the pressure. No clear conclusion is not given yet, but it was suggested that the PSD generation is mainly attributed to the fatigue of the vessel wall due to the pressure fluctuation.
Numerical Analysis: The steepening of flow in an elastic pipe with constriction was studied by 1-D wave analysis. The Navier-Stokes equation was solved for the steady and unsteady flows in the 2D and 3D pipe with contraction of arbitrary shape. The flow factors affecting the PSD generation were studied for the wide range of Re number, contraction ratio and frequency.
Further investigation will be continued remarking the wall elasticity and fatigue.
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