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Study for high-dose-rate interstitial radiation therapy using remote after-loading technique

Research Project

Project/Area Number 63480251
Research Category

Grant-in-Aid for General Scientific Research (B)

Allocation TypeSingle-year Grants
Research Field Radiation science
Research InstitutionOsaka University

Principal Investigator

MASAKI Norie  Osaka University Medical School Assoc.Prof., 医学部, 助教授 (60028511)

Co-Investigator(Kenkyū-buntansha) HAYAMI Akimune  Osaka University Dental School Assist.Prof., 歯学部, 講師 (30028477)
FUCHIHATA Hajime  Osaka University Dental School Professor, 歯学部, 教授 (70028728)
IKEDA Hiroshi  Osaka University Medical School Assist.Prof., 医学部, 講師 (10028623)
Project Period (FY) 1988 – 1989
Project Status Completed (Fiscal Year 1989)
Budget Amount *help
¥5,300,000 (Direct Cost: ¥5,300,000)
Fiscal Year 1989: ¥1,700,000 (Direct Cost: ¥1,700,000)
Fiscal Year 1988: ¥3,600,000 (Direct Cost: ¥3,600,000)
KeywordsInterstitial radiation therapy / Iriduim-192 / Tongue Cancer / Remote after-loading interstitial irradiation / イリジウムー192 / インジウムー192
Research Abstract

Interstitial radiation therapy has played an important role in the management of cancer treatment for head and neck cancer, especially for cancer in the oral cavity. Disadvantages by this conventional interstitial therapy is weighted against the hospitalization of the patients and possible risks due to the radiation exposure to the medical staff. The use of high dose-rate after-loading techniques using Ir-192 has assured this procedure without personal exposure to ionizing radiation during the implantation, and without hospitalization of the patients.
By this remote after-loading technique, the rigid guide needles or applicators (non-radioactive) are introduced first and subsequently inserting the Ir-192 afterloading sources. Several new applicators for use in the oral cavity has been developed. The dose distribution when using these applicators for single plane implant and/or for double plane implants are studied.
Optimum delivery dose by this high dose-rate interstitial therapy should be different from conventional low dose-rate interstitial radiation therapy, with possible dose effect factor 1.5-2.0, although more clinical experience is needed.

Report

(3 results)
  • 1989 Annual Research Report   Final Research Report Summary
  • 1988 Annual Research Report
  • Research Products

    (17 results)

All Other

All Publications (17 results)

  • [Publications] Nakamura,M.,Mssaki,N.,et al: "A histological Grading of Malignancy of Squamous Cell Carcinoma of the Tongue." Oral Radiol. 4. 7-13 (1988)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Masaki,N.,et al: "Results of Interstitial Radiation Therapy with Iridium-192 for Patients with Carcinoma of the Oral Tongue." Oral Radiol. 4. 125-131 (1988)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] 真崎規江: "舌癌治療の問題点" 耳鼻と臨床. 13. 1368-1372 (1988)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] 久保和子,真崎規江,他: "舌癌Tx症例の放射線治療" 癌の臨床. 35. 264-269 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] 真崎規江,他: "口腔癌治療における形態と機能温存と放射線治療の役割" 癌と化学療法. 16. 3105-3110 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Masaki,N.,et al.: "Study for high-dose-rate interstitial radiation therapy using remote after-loading technique" Oral Radiol(予定). 6. (1990)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Nakamura, M., Mssaki, N., et al.: "A histological Grading of Malignancy of Squamous Cell Carcinoma of the Tongue." Oral Radiol 4(1) 1988.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Masaki, N., et al.: "Results of Interstitial Radiation Therapy with Iridium-192 for Patients with Carcinoma of the Oral Tongue." Oral Radiol 4(2) 1988.12.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] Masaki, N., et al.: "Study for high-dose-rate interstitial radiation therapy using remote after-loading technique." Oral Radiol 6 1990.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1989 Final Research Report Summary
  • [Publications] 真崎規江、他: "下顎歯肉癌に対するブレオマイシンまたはペプロマイシンと放射線治療併用による成績" 頭頚部腫瘍. 15. 69-72 (1989)

    • Related Report
      1989 Annual Research Report
  • [Publications] 真崎規江、他: "悪性リンパ腫の予後因子" 癌の臨床. 35. 1591-1595 (1989)

    • Related Report
      1989 Annual Research Report
  • [Publications] 真崎規江、他: "口腔癌治療における形態と機能温存と放射線治療の役割" 癌と化学療法. 16. 3105-3110 (1989)

    • Related Report
      1989 Annual Research Report
  • [Publications] Masaki,N. et al.: "Study for high-dose-rate interstitial radiation therapy using remote after-loading technique" Oral Radiol.

    • Related Report
      1989 Annual Research Report
  • [Publications] Norie Masaki: Oral Radiology. 4. (1988)

    • Related Report
      1988 Annual Research Report
  • [Publications] M.Nakamura: Oral Radiology. 4. 7-13 (1988)

    • Related Report
      1988 Annual Research Report
  • [Publications] 真崎規江: 耳鼻と臨床. 34. 1368-1372 (1988)

    • Related Report
      1988 Annual Research Report
  • [Publications] 久保和子: 日本医放会誌. 48. 873-880 (1988)

    • Related Report
      1988 Annual Research Report

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Published: 1988-04-01   Modified: 2016-04-21  

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